中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

1465 records (took 0.027 seconds)

    BACTERIAL HOST STRAIN
    131.
    发明专利
    BACTERIAL HOST STRAIN 未知

    公开(公告)号：SG10201606462WA

    公开(公告)日：2016-09-29

    申请号：SG10201606462W

    申请日：2010-09-23

    Applicant: UCB PHARMA SA

    Inventor： ELLIS MARK ,  HUMPHREYS DAVID PAUL

    Abstract: A recombinant gram-negative bacterial cell comprising one or more of the following mutated protease genes: a. a mutated Tsp gene, wherein the mutated Tsp gene encodes a Tsp protein having reduced protease activity or is a knockout mutated Tsp gene; b. a mutated ptr gene, wherein the mutated ptr gene encodes a Protease III protein having reduced protease activity or is a knockout mutated ptr gene; and c. a mutated DegP gene encoding a DegP protein having chaperone activity and reduced protease activity ; wherein the cell is isogenic to a wild-type bacterial cell except for the mutated Tsp gene and/or mutated ptr gene and/or mutated Deg P gene and optionally a polynucleotide sequence encoding a protein of interest.

    Bacterial host strain
    137.
    发明专利
    Bacterial host strain 未知

    公开(公告)号：AU2016201536A1

    公开(公告)日：2016-03-24

    申请号：AU2016201536

    申请日：2016-03-09

    Applicant: UCB PHARMA SA

    Inventor： ELLIS MARK ,  HUMPHREYS DAVID PAUL

    IPC: C12N9/50 ,  C12P21/00

    Abstract: A recombinant gram-negative bacterial cell comprising one or more of the following mutated protease genes: a. a mutated Tsp gene, wherein the mutated Tsp gene encodes a Tsp protein having reduced protease activity or is a knockout mutated Tsp gene; b. a mutated ptr gene, wherein the mutated ptr gene encodes a Protease III protein having reduced protease activity or is a knockout mutated ptr gene; and c. a mutated DegP gene encoding a DegP protein having chaperone activity and reduced protease activity ; wherein the cell is isogenic to a wild-type bacterial cell except for the mutated Tsp gene and/or mutated ptr gene and/or mutated Deg P gene and optionally a polynucleotide sequence encoding a protein of interest. 7493670_1 (GHMatters) P89876.AU.1

Patent Agency Ranking