公开(公告)号：JP4421683B2

公开(公告)日：2010-02-24

申请号：JP50093298

申请日：1997-06-05

Applicant: ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア

Inventor： コイケ・マサト

IPC: G02B5/32 ,  G01J3/18 ,  G02B5/18 ,  G03H1/04

CPC classification number: G02B5/1857 ,  G01J3/1838 ,  G02B5/32

公开(公告)号：JP2009512906A

公开(公告)日：2009-03-26

申请号：JP2008537867

申请日：2006-10-24

Applicant: アイティーティー マニュファクチャリング エンタープライジーズ, インコーポレイテッド

Inventor： アンソニー ブレセンハン ケイ，

IPC: G02B5/32 ,  G02B5/18

CPC classification number: G01J3/1838 ,  G02B5/1838 ,  G03H1/02 ,  G03H1/0248 ,  G03H1/0252 ,  G03H2001/0264 ,  G03H2222/15 ,  G03H2240/55 ,  G03H2250/32 ,  G03H2250/37 ,  G03H2260/10

Abstract: 体積位相ホログラフィック回折格子デバイスが提供される。 この体積位相ホログラフィック回折デバイスは、非常に短い波長の光、例えば、紫外（ＵＶ）スペクトル領域における光と共に用いるために最適化され得る。 このデバイスは、カバーおよび基板を含み、カバーおよび基板の両方は、ガラス材料から形成されている。 ゼラチン材料の層が、カバー部材と基板部材との間に配置され、ホログラフィックに形成された可変屈折率がこの層に形成され、干渉パターンを設けている。 ゼラチン材料は、０．５ミクロン〜１ミクロンの厚さを有しており、この厚さは、ＵＶスペクトル領域における光を回折するのに適し、長寿命であり、非常に効率的である。

公开(公告)号：US20240230407A9

公开(公告)日：2024-07-11

申请号：US18319615

申请日：2023-05-18

Applicant: Wayne State University

Inventor： Gregory William Auner ,  Michelle Ann Brusatori ,  Changhe Huang

IPC: G01J3/44 ,  G01J3/02 ,  G01J3/18 ,  G01J3/28 ,  G01N21/03

CPC classification number: G01J3/44 ,  G01J3/0208 ,  G01J3/1838 ,  G01J3/2803 ,  G01N21/03 ,  G01J2003/1861

Abstract: Apparatuses, systems, and methods for Raman spectroscopy are described. In certain implementations, a spectrometer is provided. The spectrometer may include a plurality of optical elements, comprising an entrance aperture, a collimating element, a volume phase holographic grating, a focusing element, and a detector array. The plurality of optical elements are configured to transfer the light beam from the entrance aperture to the detector array with a high transfer efficiency over a preselected spectral band.

公开(公告)号：US20190150748A1

公开(公告)日：2019-05-23

申请号：US16241628

申请日：2019-01-07

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. ISLAM

IPC: A61B5/00 ,  G01J3/42 ,  G01N33/49 ,  G01J3/28 ,  G01N21/88 ,  G01J3/453 ,  G01N21/359 ,  A61B5/1455 ,  G01J3/02 ,  A61B5/145 ,  G01J3/14 ,  G01J3/10 ,  G01N33/15 ,  G16H40/67 ,  G01N33/02 ,  G01N33/44 ,  G01N21/35 ,  G01N21/39 ,  G01N21/3563

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302 ,  Y02A90/26

Abstract: A smart phone or tablet includes a first part having at least one laser diode configured to be pulsed, and a second part having at least one other laser diode, the laser diodes configured to generate near-infrared light, wherein at least some of the laser diodes comprise a distributed Bragg reflector, with some laser diode light directed to tissue including skin. An array of laser diodes generates near-infrared light and includes one or more distributed Bragg reflectors. An assembly in front of the array to forms light spots on the tissue. A first receiver includes detectors that receive light reflected from the tissue. An infrared camera generates data from light reflected from the tissue. The smart phone or tablet generates a two-dimensional or three-dimensional image or mapping using the infrared camera data, and includes a wireless receiver, a wireless transmitter, a display, a voice input module, and a speaker.

公开(公告)号：US20180317776A1

公开(公告)日：2018-11-08

申请号：US16029611

申请日：2018-07-08

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. ISLAM

IPC: A61B5/00 ,  G01J3/42 ,  A61B5/145 ,  A61B5/1455 ,  G01N21/359 ,  G01N21/39 ,  G01N33/49 ,  G01N21/88 ,  G01J3/02 ,  G01J3/10 ,  G01J3/14 ,  G01J3/28 ,  G01N21/3563 ,  G01N21/35 ,  G01N33/44 ,  G01N33/15 ,  G01N33/02 ,  G01J3/453 ,  G01J3/18 ,  G01J3/12 ,  G01M3/38 ,  G01N21/85 ,  G01N21/95 ,  H01S3/00 ,  H01S3/30 ,  H01S3/067

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302

Abstract: A smart phone or tablet includes pulsed laser diodes generating light with near-infrared wavelengths between 700-2500 nanometers. First lenses direct light from the laser diodes to tissue. An array of pulsed laser diodes generates light with near-infrared wavelengths between 700-2500 nanometers. Second lenses form light from the array into spots directed on the tissue. An infrared camera synchronized to the laser diodes and the array generates data based on light reflected from the tissue. The smart phone or tablet generates a two-dimensional or three-dimensional image using the data from the infrared camera. The smart phone or tablet includes a wireless receiver, a wireless transmitter, a display, a voice input module, and a speaker.

公开(公告)号：US20180120280A1

公开(公告)日：2018-05-03

申请号：US15855201

申请日：2017-12-27

Applicant: Omni Medsci, Inc.

Inventor： Mohammed N. ISLAM

IPC: G01N33/15 ,  A61B5/00 ,  A61B5/1455 ,  A61B5/145 ,  G01J3/10 ,  G01J3/28 ,  G01J3/453 ,  G01N21/359 ,  G01N21/3563 ,  G01N21/39 ,  G01N21/88 ,  G01N33/02 ,  G01N33/44 ,  G01N33/49

CPC classification number: G01N33/15 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/0088 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/3504 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/88 ,  G01N33/02 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3513 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  H01S3/302

Abstract: A measurement system includes a light source having semiconductor sources configured to generate an input optical beam, a multiplexer configured form an intermediate optical beam from the input optical beam, fibers including a fused silica fiber configured to receive the intermediate optical beam and to form an output optical beam. The output optical beam comprises wavelengths between 700 and 2500 nanometers with a bandwidth of at least 10 nanometers. A measurement apparatus is configured to deliver the output beam to a sample to generate a spectroscopy output beam. A receiver is configured to receive and process the spectroscopy output beam to generate an output signal, wherein the receiver processing includes chemometrics or multivariate analysis methods to permit identification of materials within the sample, the light source and the receiver are remote from the sample, and the sample includes plastics or food industry goods.

公开(公告)号：US20170367585A1

公开(公告)日：2017-12-28

申请号：US15686198

申请日：2017-08-25

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. ISLAM

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1455 ,  G01J3/10 ,  G01J3/28 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N33/49 ,  G01N33/44 ,  G01N33/15 ,  G01N33/02 ,  G01N21/88 ,  G01J3/453 ,  G01M3/38 ,  H01S3/30 ,  G01J3/14 ,  G01J3/18

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302

Abstract: A wearable device for use with a smart phone or tablet includes LEDs for measuring physiological parameters by modulating the LEDs and generating a near-infrared multi-wavelength optical beam. At least one LED emits at a first wavelength having a first penetration depth and at least another LED emits at a second wavelength having a second penetration depth into tissue. The device includes lenses that deliver the optical beam to the tissue, which reflects the first and second wavelengths. A receiver is configured to capture light while the LEDs are off and while at least one of the LEDs is on and to difference corresponding signals to improve a signal-to-noise ratio of the optical beam reflected from the tissue. The signal-to-noise ratio is further increased by increasing light intensity of at least one of the LEDs. The device generates an output signal representing a non-invasive measurement on blood within the tissue.

公开(公告)号：US09594201B2

公开(公告)日：2017-03-14

申请号：US14414610

申请日：2013-07-15

Applicant: The University of North Carolina at Chapel Hill

Inventor： J. Christopher Clemens ,  Darragh Evelyn Anthony Adam O'Donoghue

IPC: G02B5/32 ,  G01J3/45 ,  G01J3/02 ,  G03H1/04 ,  G03H1/18 ,  G03H1/02 ,  G03H1/00 ,  G01J3/10 ,  B29D11/00

CPC classification number: G02B5/32 ,  B29D11/00769 ,  G01J3/021 ,  G01J3/10 ,  G01J3/1838 ,  G01J3/45 ,  G01J2003/102 ,  G01J2003/452 ,  G03H1/0005 ,  G03H1/0248 ,  G03H1/041 ,  G03H1/181 ,  G03H2001/026 ,  G03H2001/0439 ,  G03H2001/185

Abstract: The subject matter described herein includes a curved VPH grating with tilted fringes and spectrographs, both retroreflective and transmissive, that use such gratings. A VPH grating according to the subject matter described herein includes a first curved surface for receiving light to be diffracted. The grating includes an interior region having tilted fringes to diffract light that passes through the first surface. The grating further includes a second curved surface bounding the interior region on a side opposite the first surface and for passing light diffracted by the fringes.

Abstract translation: 本文描述的主题包括具有倾斜条纹的弯曲VPH光栅和使用这种光栅的回射和透射的光谱仪。 根据本文所述的主题的VPH光栅包括用于接收待衍射的光的第一弯曲表面。 光栅包括具有倾斜条纹的内部区域，以衍射通过第一表面的光。 光栅还包括第二弯曲表面，其在与第一表面相对的一侧上限定内部区域，并且用于使由条纹衍射的光通过。

公开(公告)号：US09494567B2

公开(公告)日：2016-11-15

申请号：US14650897

申请日：2013-12-17

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. Islam

IPC: G01J3/00 ,  G01N33/15 ,  A61B5/1455 ,  A61B5/00 ,  G01J3/10 ,  G01J3/28 ,  G01J3/453 ,  G01N21/359 ,  A61B5/145 ,  G01N33/49 ,  H01S3/30 ,  G01J3/14 ,  G01J3/18

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302

Abstract: Non-invasive monitoring of blood constituents such as glucose, ketones, or hemoglobin A1c may be accomplished using near-infrared or short-wave infrared (SWIR) light sources through absorbance, diffuse reflection, or transmission spectroscopy. As an example, hydro-carbon related substances such as glucose or ketones have distinct spectral features in the SWIR between approximately 1500 and 2500 nm. An SWIR super-continuum laser based on laser diodes and fiber optics may be used as the light source for the non-invasive monitoring. Light may be transmitted or reflected through a tooth, since an intact tooth and its enamel and dentine may be nearly transparent in the SWIR. Blood constituents or analytes within the capillaries in the dental pulp may be detected. The non-invasive monitoring device may communicate with a device such as a smart phone or tablet, which may transmit a signal related to the measurement to the cloud with cloud-based value-added services.

Abstract translation: 通过吸收，漫反射或透射光谱可以使用近红外或短波红外（SWIR）光源实现对血液成分如葡萄糖，酮或血红蛋白A1c的非侵入性监测。 作为示例，水 - 碳相关物质如葡萄糖或酮在SWIR中在约1500和2500nm之间具有不同的光谱特征。 可以使用基于激光二极管和光纤的SWIR超连续激光器作为非侵入性监测的光源。 光可以通过牙齿传播或反射，因为完整的牙齿及其牙釉质和牙质在SWIR中可能几乎是透明的。 可以检测牙髓中毛细血管内的血液成分或分析物。 非侵入式监测设备可以与诸如智能电话或平板电脑的设备进行通信，智能电话或平板电脑可以使用基于云的增值业务将与测量相关的信号传输到云。

公开(公告)号：US09222831B2

公开(公告)日：2015-12-29

申请号：US14234663

申请日：2012-05-28

Applicant: Takafumi Yokino ,  Katsumi Shibayama ,  Masaki Hirose ,  Katsuhiko Kato

Inventor： Takafumi Yokino ,  Katsumi Shibayama ,  Masaki Hirose ,  Katsuhiko Kato

IPC: G01J3/28 ,  G01J3/02 ,  G01J3/18 ,  G01J3/24

CPC classification number: G01J3/0205 ,  G01J3/0202 ,  G01J3/0256 ,  G01J3/0262 ,  G01J3/0291 ,  G01J3/1838 ,  G01J3/24 ,  G01J3/2803 ,  G01J2003/1852

Abstract: A spectroscope comprises a package provided with a light entrance part, a plurality of lead pins penetrating through a support part opposing the light entrance part in the package, a light detection unit supported on the support part within the package, and a spectroscopic unit supported on the support part within the package so as to be arranged on the support part side of the light detection unit. The light detection unit has a light transmission part for transmitting therethrough light incident thereon from the light entrance part. The spectroscopic unit has a spectroscopic part for spectrally resolving the light transmitted through the light transmission part while reflecting the light to a light detection part. The lead pins are fitted into fitting parts provided with the light detection unit and electrically connected to the light detection part.

Abstract translation: 分光镜包括设置有光入射部的多个引线，穿过与封装体内的光入射部相对的支撑部的多个引脚，支撑在封装内的支撑部上的光检测部， 所述支撑部分在所述包装内，以布置在所述光检测单元的所述支撑部分侧上。 光检测单元具有用于透射从入射部入射到其上的光的光透射部。 分光单元具有分光部分，用于在将光反射到光检测部分的同时光谱分辨透过透光部分的光。 导引针安装在配备有光检测单元的配件中并电连接到光检测部件。