Abstract:
The present invention relates to a method and an apparatus for a fast thermo-optical characterisation of particles. In particular, the present invention relates to a method and a device to measure the stability of (bio)molecules, the interaction of molecules, in particular biomolecules, with, e.g. further (bio)molecules, particularly modified (bio)molecules, particles, beads, and/or the determination of the length/size (e.g. hydrodynamic radius) of individual (bio)molecules, particles, beads and/or the determination of length/size (e.g. hydrodynamic radius).
Abstract:
A flow analyzer includes a flow body having a single-piece construction. The flow body includes a flow path extending through the flow body along a flow direction between opposing inlet and outlet ports and an enclosed wiring conduit extending substantially transverse to the flow direction between a first side of the flow body and a second side of the flow body. The enclosed wiring conduit is isolated from the flow path. An illumination unit is disposed on the first side of the flow body and configured to illuminate fluid within the flow path. An observation unit is disposed on the second side of the flow body and configured to visually observe the fluid within the flow path.
Abstract:
A system for inspecting a backside surface of a wafer with multi-channel focus control includes a set of inspection sub-systems including a first inspection sub-system positioned and an additional inspection sub-system. The first and additional inspection sub-systems include an optical assembly, an actuation assembly, where the optical assembly is disposed on the actuation assembly, and a positional sensor configured to sense a position characteristic between a portion of the optical assembly and the backside surface of the wafer. The system also includes a controller configured to acquire one or more wafer profile maps of the backside surface of the wafer and adjust a first focus position of the first inspection sub-system or an additional focus position of the additional inspection sub-system based on the received one or more wafer profile maps.
Abstract:
A wafer inspection apparatus including a light emitter configured to emit light onto a to-be-inspected surface of a wafer, an imaging unit configured to obtain an image formed by the light emitted from the light emitter and reflected by the to-be-inspected surface, a moving unit configured to move a to-be-inspected position on the to-be-inspected surface by controlling a position of one of the wafer and the light emitter, and an inspecting unit configured to inspect the to-be-inspected surface by detecting a scatter image formed by the light that is emitted from the light emitter and scattered by a defect of the to-be-inspected surface, where the scatter image is formed outside an outline of the image formed by the light emitted from the light emitter.
Abstract:
Provided is a small and easy-to-carry light-induced fluorescence measuring device capable of minimizing alignment displacements in an optical system due to impact and so forth, suppressing reflected light and scattered light and so forth from entering a fluorescence measuring unit, and capable of carrying out fast and high-performance measurements. A laser light source (1) for emitting excitation light, a sample case (2), a photomultiplier tube (4) constituting the fluorescence measuring unit, a fluorescence collecting optical system (3) and so forth are embedded in a resin material (6) that is transparent to the excitation light and the light including fluorescence emitted from a sample (S). The resin material (6) is provided in at least part of a light path that guides the fluorescence in the fluorescence collecting optical system (3), and this resin forms a housing that holds the laser light source (1), the fluorescence collecting optical system (3), the photomultiplier (4) and so forth. A pigment having wavelength characteristics for absorbing the excitation light, Raman light generated from the resin, and so forth is contained substantially in a uniform manner in a resin region (61) that surrounds the light path through which the excitation light and the light including the fluorescence pass, so as to absorb all these types of light travelling outside the light path.
Abstract:
Motion strategies in two and three dimensions for scanning microscope imaging are described. An object, sample, or specimen is mounted on a precision three- dimensional stage. The object is moved concurrently with respect to a first axis and a second axis orthogonal to the first against a cutting tool to cut the object. An image of the cut portion is generated as the object is moved. The cutting tool may act as an optical waveguide for illuminating the portion of the object cut. An optical element captures images of the cut and illuminated object. The object may further be concurrently moved with respect to a third axis orthogonal to both the first and second.
Abstract:
A liquid measuring system for producing one or more property values of a liquid. The system can include: a thin film device and one or more measuring devices for measuring said one or more property values. The system includes a thin film device for producing a thin film of the liquid on a spinning disk. The system is particularly useful for measuring color and appearance properties of the liquid. The system can be useful for producing coating compositions.