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公开(公告)号：EP0283802A3
公开(公告)日：1990-03-14
申请号：EP88103398.9
申请日：1988-03-04
Applicant: ABBOTT LABORATORIES
Inventor： Houseman, Kenneth Russell , Wender, David C. , Banovez, Lawrence George , Wroblewski, Mieczyslaw
IPC: G01N21/59 , G01N21/47 , G01N33/53 , G01N33/543
CPC classification number: G01N21/253 , G01J2003/123 , G01N2201/0407 , G01N2201/0826 , Y10S436/807
Abstract: A vertical beam spectrophotometer for measuring the light absorption of an assay prepared using standard wet chemistry procedures and conventional solid phase coated bead technology is disclosed. The spectrophotometer measures the absorption of the assay in a conventional reaction cuvette with the bead remaining in the cuvette. The light source of the spectrophotometer illuminates the bead, which diffuses the light into the surrounding assay solution. A lense projects the diffused light onto a photocell which converts it into an electrical signal having magnitude related to the light absorption of the assay. The signal is processed in a known manner by conventional processing circuitry to obtain an absorption value.
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公开(公告)号：EP0347951A2
公开(公告)日：1989-12-27
申请号：EP89114580.7
申请日：1985-06-25
Applicant: WAKO PURE CHEMICAL INDUSTRIES, LTD.
Inventor： Sakata, Yoshitsugu , Oishi, Haruki , Hatayama, Yasumichi , Shiraishi, Hiromi , Yanagisawa, Kazuya
IPC: G01N33/48
CPC classification number: G01N33/579 , G01N21/83 , G01N33/50 , G01N2201/0407 , Y10S436/805
Abstract: Endotoxin contents in samples can be determined qualitatively or quantitatively, singly or in parallel, with high precision in a short time by a process comprising applying a light to each sample solution, measuring an initial transmitted light amount I₀ and a transmitted light amount at a time t, I(t), to give a ratio R(t) = I(t)/I₀, and judging a gelation point by a threshold value of R(t), or further obtaining a gelation time from the gelation point. An apparataus used therefor is also disclosed.
Abstract translation: 样品中的内毒素含量可以通过包括向每个样品溶液施加光，一次测量初始透射光量I0和透射光量的方法，在短时间内以高精度定性或定量地，单独或并行地测定 t，I（t），得到比例R（t）= I（t）/ I0，并且通过R（t）的阈值判断凝胶化点，或进一步从凝胶化点获得凝胶化时间。 还公开了一种用于其的设备。
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公开(公告)号：EP0173021A3
公开(公告)日：1986-10-08
申请号：EP85107877
申请日：1985-06-25
Applicant: WAKO PURE CHEMICAL INDUSTRIES, LTD.
Inventor： Sakata, Yoshitsugu , Oishi, Haruki , Hatayama, Yasumichi , Shiraishi, Hirome , Yanagisawa, Kazuya
IPC: G01N33/50 , G01N33/579 , G01N21/83
CPC classification number: G01N33/579 , G01N21/83 , G01N33/50 , G01N2201/0407 , Y10S436/805
Abstract: 57 Endotoxin contents in samples can be determined qualitatively or quantitatively, singly or in parallel, with high precision in a short time by a process comprising applying a light to each sample solution, measuring an initial transmitted light amount l o and a transmitted light amount at a time t, I(t), to give a ratio R(t) = l(t)/l o , and judging a gelation point by a threshold value of R(t), or further obtaining a gelation time from the gelation point. An apparatus used therefore is also disclosed.
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公开(公告)号：EP2905605A1
公开(公告)日：2015-08-12
申请号：EP14382043.9
申请日：2014-02-06
Applicant: Fundació Institut de Ciències Fotòniques , Institució Catalana De Recerca I Estudis Avançats (ICREA)
Inventor： Pruneri, Valerio , Martínez, Pedro A. , Jofre, Marc
IPC: G01N21/47 , G01N21/53 , G01N21/57 , G01N21/958
CPC classification number: G01N21/47 , G01N21/4738 , G01N21/534 , G01N21/57 , G01N2021/555 , G01N2021/556 , G01N2201/0407
Abstract: Apparatus for measuring light scattering of a sample comprising a light beam source, means for collimating the beam and making it impinge on the sample in a perpendicular direction, at least one light sensor, and at least one spatial filter between the sample and the optical sensor, provided with two apertures, means for measuring the total power reaching the sensor and means for measuring the power of beams with a low k vector after the beam traverses the filter. The invention provides thus a simplified, portable and compact device for measuring different parameters like haze, turbidity, etc. can be built, for any sample and without the need of changing detectors.
Abstract translation: 用于测量包括光束源的样品的光散射的装置，用于准直光束并使其沿垂直方向撞击在样品上的装置，至少一个光传感器以及样品和光学传感器之间的至少一个空间滤光器 设置有两个孔，用于测量到达传感器的总功率的装置和用于在光束穿过滤光器之后用低k矢量测量光束的功率的装置。 因此，本发明提供了一种用于测量不同参数（如雾度，浊度等）的简化的便携式和紧凑型装置，可用于任何样品并且不需要改变检测器。
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公开(公告)号：EP2895843A1
公开(公告)日：2015-07-22
申请号：EP13759987.4
申请日：2013-09-11
Inventor： KOZMA, Peter , EHRENTREICH-FÖRSTER, Eva , SCHUMACHER, Soeren
IPC: G01N21/64
CPC classification number: G01N21/6454 , G01N21/0303 , G01N21/648 , G01N21/7703 , G01N2201/0407 , G01N2201/0642
Abstract: The invention relates to a measuring device for luminescence measurement comprising a sample carrier (8) for receiving a luminescent sample (9), a first lens array (13) having numerous lenses (14) arranged in a grid-shaped fashion and serving for focusing luminescent radiation emerging from the luminescent sample (9), and comprising a light sensor (16) for detecting the luminescent radiation emitted by the luminescent sample (9), wherein the light sensor (16) is arranged downstream of the first lens array (13) in the beam path of the luminescent radiation. It is proposed that the first lens array (13) is a first microlens array (13) having numerous microlenses (14), wherein a first perforated mask (11) having numerous holes (12) is arranged in the beam path of the luminescent radiation between the sample carrier (8) and the first microlens array (13), wherein the individual microlenses (14) and the holes (12) are assigned to one another and have corresponding axes. The sample carrier (8) can have a substantially planar waveguide (8), wherein the excitation radiation from an illumination unit (1) is coupled into a waveguide edge (10) of the waveguide (8).
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Patent Agency Ranking
公开(公告)号：EP2859325A2
公开(公告)日：2015-04-15
申请号：EP13736975.7
申请日：2013-06-06
Applicant: Bio-Rad Laboratories, Inc.
Inventor： URI, Yochanan , RAN, Boaz , NOTCOVICH, Ariel G. , NIMRI, Shay
CPC classification number: G01N21/553 , G01N21/253 , G01N21/658 , G01N33/54373 , G01N2021/0328 , G01N2201/0407 , G01N2201/0484 , G01N2201/062
Abstract: A tip for use in an optical detection system to analyze an analyte in a fluid sample drawn into the tip, using light reflected from a detection surface inside the tip that the analyte binds to, comprising a first detection surface and a second detection surface located in a same flow path with no controllable valve separating them, wherein the first and second detection surfaces have different surface chemistries.
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公开(公告)号：EP1830174B1
公开(公告)日：2014-07-16
申请号：EP07011773.4
申请日：2006-01-03
Applicant: Samsung Electronics Co., Ltd.
Inventor： Ok, Gyeong-sik , Kim, Su-hyeon , Kim, Jin-tae , Oh, Kwang-wook
CPC classification number: G01J3/10 , G01J3/02 , G01J3/0218 , G01J3/0256 , G01J3/4406 , G01J2003/1213 , G01N21/05 , G01N21/6452 , G01N21/6456 , G01N2021/0346 , G01N2021/3174 , G01N2021/6419 , G01N2021/6421 , G01N2021/6471 , G01N2021/6484 , G01N2201/0221 , G01N2201/0407 , G01N2201/0461 , G01N2201/0612 , G01N2201/0627 , G01N2201/0631 , G01N2201/0806 , G01N2201/0833
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公开(公告)号：EP1991860A2
公开(公告)日：2008-11-19
申请号：EP07717653.5
申请日：2007-02-23
Applicant: GENERAL ELECTRIC COMPANY
Inventor： FOMITCHOV, Pavel A. , BARASH, Eugene , YEKTA, Ahmad , MASINO, Joseph
IPC: G01N23/00
CPC classification number: G01N21/6458 , G01N21/47 , G01N2201/0407 , G01N2201/1042 , G02B21/0048 , G02B21/0076 , G02B21/367
Abstract: A system and method for multimode imaging of at least one sample is disclosed. The system includes at least one light source; an optical system selected responsive to a mode of operation of the imaging system; and a detector capable of selective reading of pixels. The at least one sample is moved relative to the optical system using a sample movement technique selected from the group consisting of step sample moving and continuous sample moving. The method includes the steps of (1) selecting a mode of operation for the imaging system; (2) transmitting light from at least one light source through an optical system selected in response to the mode of operation for the imaging system; (3) moving the at least one sample relative to the optical system using a sample movement technique selected from the group consisting of step sample moving and continuous sample moving; and (4) selectively reading pixels with a detector.
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149.发明公开Multi-channel fluorescence measuring optical system and multi-channel fluorescence sample analyzer 有权多通道荧光测量光学系统和多通道荧光样品分析仪
公开(公告)号：EP1830174A2
公开(公告)日：2007-09-05
申请号：EP07011773.4
申请日：2006-01-03
Applicant: Samsung Electronics Co., Ltd
Inventor： Ok, Gyeong-sik , Kim, Su-hyeon , Kim, Jin-tae , Oh, Kwang-wook
CPC classification number: G01J3/10 , G01J3/02 , G01J3/0218 , G01J3/0256 , G01J3/4406 , G01J2003/1213 , G01N21/05 , G01N21/6452 , G01N21/6456 , G01N2021/0346 , G01N2021/3174 , G01N2021/6419 , G01N2021/6421 , G01N2021/6471 , G01N2021/6484 , G01N2201/0221 , G01N2201/0407 , G01N2201/0461 , G01N2201/0612 , G01N2201/0627 , G01N2201/0631 , G01N2201/0806 , G01N2201/0833
Abstract: A multi-channel fluorescence measuring optical system and a multi-channel fluorescence sample analyzer using the optical system are provided. The multi-channel fluorescence measuring optical system, which irradiates light onto a plurality of sample channels and detecting fluorescence radiated from samples, includes: a light source (60a-d); an integrator (70) for giving the light irradiated from the light source a uniform intensity distribution; a sample holder (80) having a plurality of sample channels on which the samples (m) are mounted, wherein the samples are exited by the light emitted from the integrator; and a beam splitter (75) between the integrator and the sample holder for dividing the incident light in a predetermined ratio. Since the light intensities of fluorescence images are detected using optical fiber bundles (85a-d) and photodiodes (89a-d), the manufacturing cost can be greatly reduced, and the optical system can be miniaturized.
Abstract translation: 提供了一种多通道荧光测量光学系统和使用该光学系统的多通道荧光样本分析仪。 该多通道荧光测量光学系统包括：光源（60a-d）;以及光源（60a-d）。 积分器（70），用于使从光源照射的光具有均匀的强度分布; 具有多个样品通道的样品保持器（80），所述样品（m）安装在所述样品通道上，其中所述样品通过从所述积分器发射的光离开; 以及在积分器和样品架之间的分束器（75），用于以预定比率分割入射光。 由于使用光纤束（85a-d）和光电二极管（89a-d）检测荧光图像的光强度，所以可以大大降低制造成本，并且可以使光学系统小型化。
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150.发明授权Instrument for independently and kinetically measuring light transmission through a plurality of samples 失效由多个样本的独立动能Lichtdurchlassungsmessung的装置
公开(公告)号：EP0303524B2
公开(公告)日：2001-09-26
申请号：EP88400116.5
申请日：1988-01-20
Applicant: ASSOCIATES OF CAPE COD, INC.
Inventor： Hoyt, Joshua K.
CPC classification number: G01N21/253 , G01N2201/0407 , G01N2201/0415 , G01N2201/0476
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