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公开(公告)号：CS8907589A3
公开(公告)日：1992-01-15
申请号：CS758989
申请日：1989-12-29
Applicant: ANDRIJEVSKIJ ALEXANDR MICHAJLO , GORELIK MIKHAIL V , AVIDON SERGEI V , GORDIJEVSKAJA JEVGENIJA VASILJ , ALTMAN JELENA S , VOROZCOV GEORGIJ NIKOLAJEVIC I , DJUMAJEV KIRILL MICHAJLOVIC IN
Inventor： ANDRIJEVSKIJ ALEXANDR MICHAJLO , GORELIK MICHAIL VIKTOROVIC ING , AVIDON SERGEJ VIKTOROVIC ING , GORDIJEVSKAJA JEVGENIJA VASILJ , ALTMAN JELENA SULIMOVNA ING , VOROZCOV GEORGIJ NIKOLAJEVIC I , DJUMAJEV KIRILL MICHAJLOVIC IN
IPC: C07C201/14 , C07C205/12 , C07C25/02 , C07C205/06
CPC classification number: C07C201/14 , C07C205/12
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公开(公告)号：TW287152B
公开(公告)日：1996-10-01
申请号：TW082104718
申请日：1993-06-14
Applicant: 日本農藥股份有限公司
IPC: C07C
CPC classification number: C07C205/37 , C07C201/14 , C07C231/06 , C07C235/20 , C07C253/30 , C07C255/16 , C07C255/17
Abstract: 如下式(I) 芳香化合物之製法，乃令親電子試劑與如下式 (II)化合物(II) 反應
CC 親電子試劑 CC
(II) (I)(式中R，X1，X2，及Y如下之定義)，選擇在芳環引入取代基，並揭示由此製造之新`粌穎化合物。Abstract in simplified Chinese: 如下式(I) 芳香化合物之制法，乃令亲电子试剂与如下式 (II)化合物(II) 反应 CC 亲电子试剂 CC (II) (I)(式中R，X1，X2，及Y如下之定义)，选择在芳环引入取代基，并揭示由此制造之新`粌颖化合物。
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公开(公告)号：US09758468B2
公开(公告)日：2017-09-12
申请号：US15293507
申请日：2016-10-14
Applicant: Nippon Soda Co., Ltd.
Inventor： Hiroki Inoue , Yuzuru Sakata , Shinichi Kobayashi , Yoshikazu Ito , Takashi Kitayama
IPC: C07C209/74 , C07C17/12 , C07C17/00 , C07C201/14 , C07C209/32 , C07C205/12 , C07C211/52 , C07C17/06 , C07C201/08
CPC classification number: C07C209/74 , C07C17/00 , C07C17/06 , C07C17/12 , C07C201/08 , C07C201/14 , C07C205/12 , C07C209/32 , C07C211/52 , C07C25/13
Abstract: The present invention provides a halogenated aniline represented by formula (I) (wherein each of X1 and X2 independently represents a chlorine atom, a bromine atom or an iodine atom), a method for producing the halogenated aniline, and other aspects.
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公开(公告)号：US09346780B2
公开(公告)日：2016-05-24
申请号：US14431945
申请日：2013-10-10
Inventor： Pandurang V. Chouthaiwale , Fujie Tanaka
IPC: A61K31/35 , C07D309/16 , C07D309/28 , C07D309/30 , C07D317/30 , C07C201/14 , C07D407/04 , C07D241/44 , C07D243/02 , C07D307/54 , C07C205/55
CPC classification number: C07D309/28 , C07C201/14 , C07C205/55 , C07C2601/14 , C07D241/44 , C07D243/02 , C07D307/54 , C07D309/30 , C07D317/30 , C07D407/04
Abstract: Disclosed is a process for preparing dihydro-2H-pyran derivatives of formula I: wherein R1 and R2 are defined herein. The process of the invention provides the compound of formula I in concise cascade reactions and in one pot. The compound of formulae I prepared by the process of the invention and its further transformed derivatives are useful for making pharmaceutical composition for the treatment of proliferative diseases.
Abstract translation: 公开了制备式I的二氢-2H-吡喃衍生物的方法：其中R 1和R 2在本文中定义。 本发明的方法在简单的级联反应中和一锅中提供式I化合物。 通过本发明方法制备的式I化合物及其进一步转化的衍生物可用于制备用于治疗增殖性疾病的药物组合物。
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公开(公告)号：US08586792B2
公开(公告)日：2013-11-19
申请号：US13416454
申请日：2012-03-09
IPC: C07C231/02
CPC classification number: C07C201/14 , C07C231/02 , C07C231/24 , C07C233/65 , C07C205/58
Abstract: A process for the preparation of 4-iodo-3-nitrobenzamide free from the impurities formed due to nucleophilic substitution of the labile iodo group is disclosed.
Abstract translation: 公开了一种制备4-碘-3-硝基苯甲酰胺的方法，该方法不含由于不稳定的碘基团的亲核取代而形成的杂质。
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Patent Agency Ranking
公开(公告)号：US20130172618A1
公开(公告)日：2013-07-04
申请号：US13416454
申请日：2012-03-09
IPC: C07C231/14
CPC classification number: C07C201/14 , C07C231/02 , C07C231/24 , C07C233/65 , C07C205/58
Abstract: A process for the preparation of 4-iodo-3-nitrobenzamide free from the impurities formed due to nucleophilic substitution of the labile iodo group is disclosed.
Abstract translation: 公开了一种制备4-碘-3-硝基苯甲酰胺的方法，该方法不含由于不稳定的碘基团的亲核取代而形成的杂质。
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公开(公告)号：US06919456B2
公开(公告)日：2005-07-19
申请号：US10452082
申请日：2003-05-30
Applicant: Barry M. Trost , Hisanaka Ito
Inventor： Barry M. Trost , Hisanaka Ito
IPC: B01J23/06 , B01J31/18 , C07B53/00 , C07C45/64 , C07C45/72 , C07C45/74 , C07C201/12 , C07C205/03 , C07C205/04 , C07C205/15 , C07C205/16 , C07C205/30 , C07C205/32 , C07D207/09 , C07D211/36 , C07D207/40 , C07D405/00
CPC classification number: C07C45/64 , B01J23/06 , B01J31/1805 , B01J31/182 , B01J2231/342 , B01J2231/345 , B01J2231/40 , B01J2531/20 , B01J2531/22 , B01J2531/23 , B01J2531/26 , B01J2531/27 , C07B53/00 , C07B2200/07 , C07C45/72 , C07C45/74 , C07C201/12 , C07C201/14 , C07C269/06 , C07C2601/14 , C07D207/09 , C07C49/83 , C07C271/16 , C07C205/15 , C07C205/16 , C07C205/30 , C07C205/32 , C07C205/14 , C07C205/26
Abstract: Methods and compositions are provided for the direct catalytic asymmetric aldol reaction of aldehydes with donor molecules selected from ketones and nitroalkyl compounds. The reactions employ as catalyst a Group 2A or Group 2B metal complex of a ligand of formula I, as defined further herein.
Abstract translation: 提供方法和组合物用于醛与选自酮和硝基烷基化合物的供体分子的直接催化不对称醛醇缩合反应。 该反应使用如本文进一步定义的式I配体的2A族或2B族金属络合物作为催化剂。
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公开(公告)号：US20040019239A1
公开(公告)日：2004-01-29
申请号：US10452082
申请日：2003-05-30
Inventor： Barry M. Trost , Hisanaka Ito
IPC: C07C049/213 , C07C049/225 , C07C049/563 , C07C049/76
CPC classification number: C07C45/64 , B01J23/06 , B01J31/1805 , B01J31/182 , B01J2231/342 , B01J2231/345 , B01J2231/40 , B01J2531/20 , B01J2531/22 , B01J2531/23 , B01J2531/26 , B01J2531/27 , C07B53/00 , C07B2200/07 , C07C45/72 , C07C45/74 , C07C201/12 , C07C201/14 , C07C269/06 , C07C2601/14 , C07D207/09 , C07C49/83 , C07C271/16 , C07C205/15 , C07C205/16 , C07C205/30 , C07C205/32 , C07C205/14 , C07C205/26
Abstract: Methods and compositions are provided for the direct catalytic asymmetric aldol reaction of aldehydes with donor molecules selected from ketones and nitroalkyl compounds. The reactions employ as catalyst a Group 2A or Group 2B metal complex of a ligand of formula I, as defined further herein. 1
Abstract translation: 提供方法和组合物用于醛与选自酮和硝基烷基化合物的供体分子的直接催化不对称醛醇缩合反应。 该反应使用如本文进一步定义的式I配体的2A族或2B族金属络合物作为催化剂。
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公开(公告)号：US6100431A
公开(公告)日：2000-08-08
申请号：US88778
申请日：1998-06-02
Applicant: Neil W. Boaz
Inventor： Neil W. Boaz
IPC: C07C45/27 , C07C45/32 , C07C201/12 , C07C205/06 , C07C205/11 , C07C205/37 , C07C205/45 , C07C319/14 , C07C323/22 , C07C319/00
CPC classification number: C07C201/12 , C07C201/14 , C07C319/14 , C07C45/27 , C07C45/32
Abstract: The preparation of aromatic ketones substituted with a thioether group at the ortho position is accomplished by the initial reaction of an aromatic nucleus substituted with a halide and an ortho nitro group with a nitroalkane in the presence of a hydroxide base. The resulting ortho-nitroalkyl nitroarene compound is converted to the corresponding ortho-nitroaryl ketone by an oxidative Nef reaction. The aromatic nitro group of the ortho-nitroaryl ketone is replaced with a thioether group by reaction with a thiolate anion, most preferably under phase-transfer conditions. Aromatic ketones may be used to prepare various pharmaceutical and herbicidal compounds.
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公开(公告)号：US4788346A
公开(公告)日：1988-11-29
申请号：US54852
申请日：1987-05-27
Applicant: Michel Desbois
Inventor： Michel Desbois
IPC: B01J27/12 , C07B61/00 , C07C67/00 , C07C201/00 , C07C201/08 , C07C201/12 , C07C201/14 , C07C205/22 , C07C205/43 , C07F9/12 , C07C79/24 , C07C76/02
CPC classification number: C07C201/14
Abstract: A process for the preparation of para-nitrophenol by bringing a phenyl ester of an inorganic acid into contact with a nitrating agent in the presence of liquid hydrofluoric acid and a hydrolysis of the nitrated product obtained is carried out either simultaneously or in sequence with the nitration.
Abstract translation: 通过使无机酸的苯基酯在液体氢氟酸的存在下与硝化剂接触并且所得到的硝化产物的水解而制备对硝基苯酚的方法同时或按照硝化步骤进行 。
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