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    Luminescence measuring apparatus
    164.
    发明专利
    Luminescence measuring apparatus 有权
    发光测量装置

    公开(公告)号：JP2014006213A

    公开(公告)日：2014-01-16

    申请号：JP2012143686

    申请日：2012-06-27

    Applicant: Hitachi High-Technologies Corp ,  株式会社日立ハイテクノロジーズ

    Inventor： NODA HIDEYUKI ,  OKANOJO MASAHIRO

    IPC: G01N21/76 ,  C12M1/34 ,  G01N21/77

    CPC classification number: G01N21/76 ,  C12M1/34 ,  G01J1/0252 ,  G01N2201/0231 ,  G01N2201/1211 ,  G02B7/008 ,  H01L31/024

    Abstract: PROBLEM TO BE SOLVED: To provide a weak luminescence detecting device, in luminescence measurement, capable of: preventing dark current values or dark current pulse numbers from reducing and from fluctuating relative to temperatures; capturing luminescence signals at a high solid angle; and detecting with high sensitivity luminescence having no directivity such as chemiluminescence or bioluminescence.SOLUTION: A luminescence measuring apparatus comprises: a plate-like member for holding a holder for a container storing a sample; a luminescence detection part for detecting luminescence in the sample; a temperature control part for controlling temperature of the luminescence detection part; and an air blowing part for blowing air to a luminescence receiving surface of the luminescence detection part.

    Abstract translation: 要解决的问题：为了提供在发光测量中的弱发光检测装置，其能够：防止暗电流值或暗电流脉冲数量相对于温度的降低和波动; 捕获高立体角的发光信号; 并且检测不具有方向性的高灵敏度发光，例如化学发光或生物发光。解决方案：发光测量装置包括：用于容纳储存样品的容器的保持器的板状构件; 用于检测样品中的发光的发光检测部分; 用于控制所述发光检测部的温度的温度控制部; 以及用于将空气吹送到发光检测部的发光接收表面的吹风部。

    AUTOMATIC ANALYZER
    167.
    发明公开
    AUTOMATIC ANALYZER 审中-公开

    公开(公告)号：EP2565629A4

    公开(公告)日：2017-11-29

    申请号：EP11774939

    申请日：2011-04-25

    Applicant: HITACHI HIGH-TECHNOLOGIES CORP

    Inventor： TANOUE HIDETSUGU

    IPC: G01N21/76 ,  G02B6/26 ,  G02B6/42

    CPC classification number: G01N21/76 ,  G01N2201/0231 ,  G01N2201/08 ,  G02B6/0096 ,  G02B6/4298

    Abstract: Disclosed is an automatic analyzer which can detect a trace amount of reaction solution at a high S/N with stability. The analyzer allows a photomultiplier (111) to detect light from the reaction solution (109) containing a luminescent substance (114) through an optical window (102). To process the output from the photomultiplier to analyze the amount of the luminescent substance (114) contained in the reaction solution (109), an optical transmission system (110) is interposed between the optical window (102) and the photomultiplier (111). The optical transmission system includes a light inlet opposed to the optical window; a light outlet opposed to the light-receiving surface of the detector; and a reflector on which an incident beam of light from the light inlet is reflected to propagate to the light outlet. This configuration allows the effects of temperature-dependent noise from a flow cell (101) to be reduced while preventing a drop in the amount of light from the luminescent substance (114), thereby implementing analysis at a high S/N.

    DETECTION DEVICE, DETECTION METHOD USING SAID DETECTION DEVICE, AND DETECTION CHIP USED IN SAID DETECTION DEVICE
    168.
    发明公开
    DETECTION DEVICE, DETECTION METHOD USING SAID DETECTION DEVICE, AND DETECTION CHIP USED IN SAID DETECTION DEVICE 审中-公开
    DETEKTIONSVORRICHTUNG，DETEKTIONSVERFAHREN MIT DIESER DETEKTIONSVORRICHTUNG UND IN DIESER DETEKTIONSVORRICHTUNG VERWENDETER DETEKTIONSCHIP

    公开(公告)号：EP3064928A4

    公开(公告)日：2017-06-14

    申请号：EP14856943

    申请日：2014-10-31

    Applicant: KONICA MINOLTA INC

    Inventor： NAGAE KOSUKE ,  HIRAYAMA HIROSHI

    IPC: G01N21/03 ,  B01L3/00 ,  G01N21/13 ,  G01N21/552 ,  G01N21/64 ,  G01N33/553

    CPC classification number: G01N33/54373 ,  B01L3/5027 ,  B01L2200/16 ,  B01L2300/0636 ,  B01L2300/0654 ,  B01L2300/1816 ,  G01N1/14 ,  G01N21/0332 ,  G01N21/13 ,  G01N21/553 ,  G01N21/6428 ,  G01N21/648 ,  G01N33/553 ,  G01N2021/6439 ,  G01N2201/0231 ,  G01N2201/06113 ,  G01N2201/064

    Abstract: This detection device has a holder and a heating unit. The holder holds a detection chip that has the following: a prism that has an incidence surface and a film-formation surface; a metal film formed on said film-formation surface; trapping bodies laid out on the surface of said metal film; and a substrate that is laid out on the surface of the metal film, and together with the metal film, forms a liquid collection section in which a liquid is collected. The heating unit heats at least one of the substrate, the prism, and the metal film either while in contact therewith or without contacting same. Also, the heating unit is positioned so as to avoid the path that excitation light takes from an excitation-light emission unit to the abovementioned incidence surface.

    Abstract translation: 该检测装置具有支架和加热单元。 保持器保持检测芯片，该检测芯片具有：具有入射面和成膜面的棱镜; 在所述膜形成表面上形成的金属膜; 在所述金属膜的表面上布置的捕获体; 以及布置在金属膜表面上的基板，并且与金属膜一起形成收集液体的液体收集部分。 加热单元在与基板，棱镜和金属膜接触的同时加热基板，棱镜和金属膜中的至少一个，或者不接触基板，棱镜和金属膜。 而且，加热单元被定位成避开激发光从激发光发射单元到达上述入射表面的路径。

    AUTOMATIC ANALYZER
    170.
    发明公开
    AUTOMATIC ANALYZER 审中-公开
    自动分析仪

    公开(公告)号：EP2565629A1

    公开(公告)日：2013-03-06

    申请号：EP11774939.0

    申请日：2011-04-25

    Applicant: Hitachi High-Technologies Corporation

    Inventor： TANOUE, Hidetsugu

    IPC: G01N21/76

    CPC classification number: G01N21/76 ,  G01N2201/0231 ,  G01N2201/08 ,  G02B6/0096 ,  G02B6/4298

    Abstract: Disclosed is an automatic analyzer which can detect a trace amount of reaction solution at a high S/N with stability. The analyzer allows a photomultiplier (111) to detect light from the reaction solution (109) containing a luminescent substance (114) through an optical window (102). To process the output from the photomultiplier to analyze the amount of the luminescent substance (114) contained in the reaction solution (109), an optical transmission system (110) is interposed between the optical window (102) and the photomultiplier (111). The optical transmission system includes a light inlet opposed to the optical window; a light outlet opposed to the light-receiving surface of the detector; and a reflector on which an incident beam of light from the light inlet is reflected to propagate to the light outlet. This configuration allows the effects of temperature-dependent noise from a flow cell (101) to be reduced while preventing a drop in the amount of light from the luminescent substance (114), thereby implementing analysis at a high S/N.

    Abstract translation: 本发明公开了一种自动分析仪，其能够以高S / N稳定地检测微量反应溶液。 分析器允许光电倍增管（111）通过光学窗口（102）检测来自含有发光物质（114）的反应溶液（109）的光。 为了处理来自光电倍增管的输出以分析包含在反应溶液（109）中的发光物质（114）的量，将光学传输系统（110）插入光学窗口（102）和光电倍增器（111）之间。 光传输系统包括与光学窗口相对的光入口; 与检测器的光接收表面相对的光出口; 以及反射器，来自光入口的入射光束被反射以传播至光出口。 根据该构成，能够抑制来自流动室101的温度依赖性噪声的影响，并且能够防止来自发光物质114的光量的降低，能够实现S / N高的分析。

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