公开(公告)号：US20180073925A1

公开(公告)日：2018-03-15

申请号：US15796077

申请日：2017-10-27

Applicant: Sumitomo Electric Industries, Ltd.

Inventor： Hiroshi Suganuma ,  Takuya Okuno ,  Yuna Okina ,  Asako Motomura ,  Yoko Sugiyama

IPC: G01J3/28 ,  G01N21/359 ,  G01J3/02 ,  G01J3/10 ,  G02B21/36 ,  G02B21/06 ,  G02B21/02 ,  G02B13/22 ,  G01N33/487

CPC classification number: G01J3/2823 ,  G01J3/0208 ,  G01J3/108 ,  G01N21/27 ,  G01N21/359 ,  G01N33/487 ,  G01N2201/0633 ,  G02B13/22 ,  G02B21/0064 ,  G02B21/0096 ,  G02B21/02 ,  G02B21/06 ,  G02B21/365

Abstract: Provided is a microscope device which includes: (1) a light source that outputs illumination light in a wavelength band including a near-infrared region; (2) an illumination optical system that irradiates an observation target with the illumination light output from the light source; (3) an image formation optical system that includes a spectroscopic unit which is configured to receive and disperse transmitted or scattered light produced at the observation target by irradiating the observation target with the illumination light, and that forms an image on the basis of the dispersed transmitted or scattered light; and (4) an image capturing unit that acquires the image formed by the image formation optical system. An illumination-light-irradiated area of the observation target is larger than an area of the field of view of the image formation optical system, and is less than or equal to ten times the area of the field of view.

公开(公告)号：US09891163B2

公开(公告)日：2018-02-13

申请号：US15316878

申请日：2015-11-10

Applicant: Halliburton Energy Services, Inc.

Inventor： David L. Perkins ,  Darren G. Gascooke ,  Nagaraja Pai ,  Nathan J. Harder

IPC: G01N21/31

CPC classification number: G01N21/31 ,  G01J3/28 ,  G01N21/0303 ,  G01N21/85 ,  G01N2201/0633

Abstract: Conventional optical analysis tools containing an integrated computational element may have an operational profile that is too large for convenient use within confined locales. Optical analysis tools having a miniaturized operational profile can comprise: an electromagnetic radiation source that provides electromagnetic radiation to an optical train; and an optical computing device positioned within the optical train. The optical computing device comprises a planar array detector having at least two optical detection regions. At least one of the at least two optical detection regions has an integrated computational element disposed thereon. The planar array detector and the integrated computational element are in a fixed configuration with respect to one another.

公开(公告)号：US09863877B2

公开(公告)日：2018-01-09

申请号：US14863341

申请日：2015-09-23

Applicant: Agilent Technologies, Inc.

Inventor： Charles Hoke ,  Christopher Ryan Moon ,  Andrew Ghetler ,  Yuri Beregovski ,  Richard P. Tella ,  Yang Han

IPC: G01N21/552 ,  G01N21/35 ,  G02B13/14 ,  G02B17/00 ,  G02B17/08 ,  G01N21/3563 ,  G01N21/39 ,  G01J3/02

CPC classification number: G01N21/552 ,  G01J3/0213 ,  G01J3/0229 ,  G01N21/35 ,  G01N21/3563 ,  G01N2021/399 ,  G01N2201/0633 ,  G01N2201/10 ,  G01N2201/101 ,  G02B13/14 ,  G02B17/006 ,  G02B17/0808 ,  G02B21/002 ,  G02B21/02 ,  G02B21/04 ,  G02B21/10

Abstract: A scanner and an attenuated total reflection (ATR) objective for use in such scanners are disclosed. The ATR objective includes first and second optical elements and an input port. The input port receives an input collimated light beam that is focused to a point on a planar face of the first optical element by the second optical element such that substantially all of that portion is reflected by the planar face and no portion of the input beam strikes the planar face at an angle less than the critical angle. The second optical element also generates an output collimated light beam from light reflected from the planar thce that is characterized by a central ray that is coincident with the central ray of the input collimated light beam. A light beam converter receives the first collimated light beam and generates the input collimated light beam therefrom.

公开(公告)号：US09784986B2

公开(公告)日：2017-10-10

申请号：US14774990

申请日：2013-12-03

Applicant: Integrated Plasmonics Corporation

Inventor： Michael Yagoda Shagam ,  Robert Joseph Walters

IPC: G01N21/00 ,  G02B27/46 ,  G01N21/25 ,  G01N21/31 ,  B23K26/384 ,  B23K26/402 ,  C23C14/34 ,  C25D5/02 ,  B23K103/18

CPC classification number: G02B27/46 ,  B23K26/384 ,  B23K26/402 ,  B23K2103/18 ,  B23K2103/50 ,  C23C14/34 ,  C25D5/02 ,  G01N21/255 ,  G01N21/31 ,  G01N2201/0633 ,  G01N2201/068

Abstract: A spatial filter is made by forming a structure comprising a focusing element and an opaque surface, the opaque surface being disposed remotely from the focusing element in substantially the same plane as a focal plane of the focusing element; and by forming a pinhole in the opaque surface at or adjacent to a focal point of the focusing element by transmitting a substantially collimated laser beam through the focusing element so that a point optimally corresponding to the focal point is identified on the opaque surface and imperfection of the focusing element, if any, is reflected on the shape and position of the pinhole so formed.

公开(公告)号：US20170227397A1

公开(公告)日：2017-08-10

申请号：US15015251

申请日：2016-02-04

Applicant: Nova Biomedical Corporation

Inventor： Michael S. Cafferty ,  Scott P. Cionek

IPC: G01J3/02 ,  G01J3/42 ,  G01N21/27 ,  G01J3/14 ,  G01N33/49

CPC classification number: G01J3/0286 ,  G01J3/0202 ,  G01J3/0208 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/14 ,  G01J3/28 ,  G01J3/42 ,  G01J2003/2866 ,  G01N21/274 ,  G01N21/31 ,  G01N33/4925 ,  G01N2201/062 ,  G01N2201/0633 ,  G01N2201/0683

Abstract: An optical spectrometer for use in a COOx analyzer includes a spectrometer housing having an optical fiber housing end, a light-receiving input slit positioned adjacent the optical fiber housing end, a light dispersing element mounted to but spaced from the optical fiber housing end and positioned within an optical path along which light travels from the light-receiving input slit. The light dispersing element receives the light transmitted through the input slit and separates the light into a plurality of light beams, a light-array detector capable of receiving the plurality of light beams and converting the plurality of light beams into the electrical signal, an achromatic lens positioned in the optical path to direct the light from the input slit to the light dispersing element and to direct the plurality of light beams reflected from the light dispersing element onto the light-array detector, and a thermal-compensating means for the spectrometer housing.

公开(公告)号：US20170167979A1

公开(公告)日：2017-06-15

申请号：US15407443

申请日：2017-01-17

Applicant: Pacific Biosciences of California, Inc.

Inventor： Aaron Rulison ,  Mark McDonald ,  Paul Lundquist

IPC: G01N21/64 ,  G02B27/10 ,  G02B5/04 ,  C12Q1/68

CPC classification number: G01N21/6452 ,  C12Q1/6874 ,  G01J3/2803 ,  G01J3/36 ,  G01N21/6428 ,  G01N21/75 ,  G01N2021/6471 ,  G01N2021/6478 ,  G01N2201/0633 ,  G02B3/0056 ,  G02B3/0062 ,  G02B5/045 ,  G02B13/006 ,  G02B13/0065 ,  G02B13/0085 ,  G02B27/1013

Abstract: Apparatus, systems and methods for use in analyzing discrete reactions are provided. The analytical devices of the invention use an array of nanoscale regions (a chip) that has discrete patches, for example, patches of nanoscale regions. In some embodiments an analytical system is provided that has an analysis chip with an array of patches, each of the patches comprising nanoscale regions that emit fluorescent light when illuminated. The system has a two-dimensional (x, y) array of dichroic prisms, each prism comprising a dichroic element that diverts illumination light up in the z dimension of the array to a patch on the analysis chip above it. Each dichroic element transmits fluorescent light emitted by the patch that it illuminates, whereby the emitted light from each patch passes down through each dichroic prism. The analytical system also has a detector below the array of dichroic prisms that detects the transmitted fluorescent light. Such systems are useful for monitoring many analytical reactions at one time including single molecule sequencing reactions.

公开(公告)号：US20170138864A1

公开(公告)日：2017-05-18

申请号：US15322476

申请日：2015-06-30

Applicant: Chauvin Arnoux

Inventor： Eric Lopez ,  Vincent Huret

IPC: G01N21/85 ,  G01N21/359 ,  G01J3/02 ,  G01N21/13 ,  G01N21/11 ,  G01N33/10 ,  G01N21/3563 ,  G01N21/03

CPC classification number: G01N21/85 ,  A01D41/1277 ,  B07C5/3425 ,  G01J3/0202 ,  G01J3/0237 ,  G01J3/0289 ,  G01J3/10 ,  G01N21/0303 ,  G01N21/11 ,  G01N21/13 ,  G01N21/3563 ,  G01N21/359 ,  G01N33/10 ,  G01N2021/0339 ,  G01N2021/8466 ,  G01N2021/8592 ,  G01N2201/0633

Abstract: An arrangement for the spectrometric measurement of products, such as cereals, oleaginous products, or derived products, includes a mechanism for selective adjustment of the position of a light beam in vertical and horizontal planes, and a selective adjustment device for ensuring that rays of the light beam are parallel.

公开(公告)号：US20170030828A1

公开(公告)日：2017-02-02

申请号：US15294893

申请日：2016-10-17

Applicant: VUV Analytics, Inc.

Inventor： Dale A. Harrison ,  Anthony T. Hayes ,  Phillip Walsh

IPC: G01N21/33 ,  G01N30/74 ,  G01N33/00 ,  G01N21/05

CPC classification number: G01N30/78 ,  G01J3/02 ,  G01N21/0332 ,  G01N21/05 ,  G01N21/15 ,  G01N21/33 ,  G01N21/85 ,  G01N30/02 ,  G01N30/74 ,  G01N33/0004 ,  G01N33/0027 ,  G01N2021/0325 ,  G01N2021/151 ,  G01N2021/158 ,  G01N2021/335 ,  G01N2021/8578 ,  G01N2030/025 ,  G01N2030/027 ,  G01N2201/024 ,  G01N2201/0633 ,  G01N2201/12 ,  G01N30/7266

Abstract: An efficient absorption spectroscopy system is provided. The spectroscopy system may be configured to measure solid, liquid or gaseous samples. Vacuum ultra-violet wavelengths may be utilized. Some of the disclosed techniques can be used for detecting the presence of trace concentrations of gaseous species. A preferable gas flow cell is disclosed. Some of the disclosed techniques may be used with a gas chromatography system so as to detect and identify species eluted from the column. Some of the disclosed techniques may be used in conjunction with an electrospray interface and a liquid chromatography system so as to detect and identify gas phase ions of macromolecules produced from solution. Some of the disclosed techniques may be used to characterize chemical reactions. Some of the disclosed techniques may be used in conjunction with an ultra short-path length sample cell to measure liquids.

Abstract translation: 提供了一种有效的吸收光谱系统。 光谱系统可以被配置为测量固体，液体或气体样品。 可以使用真空紫外线波长。 一些所公开的技术可用于检测痕量浓度的气态物质的存在。 公开了一种优选的气体流通池。 所公开的技术中的一些可以与气相色谱系统一起使用，以便检测和鉴定从柱洗脱的物质。 所公开的技术中的一些可以与电喷雾界面和液相色谱系统结合使用，以便检测和鉴定由溶液产生的大分子的气相离子。 所公开的技术中的一些可以用于表征化学反应。 一些所公开的技术可以与超短路径长度的样品池结合使用以测量液体。

公开(公告)号：US20170010206A1

公开(公告)日：2017-01-12

申请号：US15114376

申请日：2014-12-04

Applicant: IMPLEN GMBH

Inventor： Thomas Sahiri

IPC: G01N21/25 ,  G01N21/03

CPC classification number: G01N21/25 ,  G01J3/0218 ,  G01N21/01 ,  G01N21/03 ,  G01N21/0303 ,  G01N21/11 ,  G01N2021/0314 ,  G01N2021/035 ,  G01N2021/6417 ,  G01N2021/6482 ,  G01N2021/6484 ,  G01N2201/062 ,  G01N2201/0633 ,  G01N2201/08

Abstract: The invention relates to a device (1) for the light spectroscopic analysis of a small amount of a liquid sample, comprising a receiving point (3) for receiving small amounts of the liquid sample, and light conductors (5, 6) which guide light of a light source to the sample and guide signal light from the sample in the direction of a detector, and is characterised in that an illumination source (7) is arranged below the receiving point (3), and a region (8) below the receiving point (3) which is permeable for the light of the illumination source (7), is provided such that the illumination light illuminates the receiving point (3).

Abstract translation: 本发明涉及一种用于少量液体样品的光谱分析的装置（1），包括用于接收少量液体样品的接收点（3）和引导光的光导体（5,6） 并且其特征在于，照明源（7）布置在所述接收点（3）的下方，并且所述区域（8）位于所述接收点 以照明光照射接收点（3）的方式设置对于照明光源（7）的光可透过的接收点（3）。

公开(公告)号：US20160356717A1

公开(公告)日：2016-12-08

申请号：US15116631

申请日：2015-02-04

Applicant: KONICA MINOLTA, INC.

Inventor： Hideyuki FUJII ,  Tetsuya NODA ,  Yukito NAKAMURA

IPC: G01N21/64 ,  G01N33/543

CPC classification number: G01N21/648 ,  G01N21/253 ,  G01N21/553 ,  G01N21/6428 ,  G01N33/54373 ,  G01N2021/6439 ,  G01N2021/6471 ,  G01N2201/0612 ,  G01N2201/0633 ,  G01N2201/068

Abstract: A surface plasmon fluorescence analysis device that has a chip holder, a light source, an angle adjustment unit, a light sensor, a filter holder, an excitation light cut filter, a scattered light transmission unit, a transmission adjustment unit, and a control unit. As seen in plan view, the area occupied by the scattered light transmission unit is arranged on the excitation light cut filter or on the filter holder and is smaller than the area of a fluorescence transmission region as seen in plan view.

Abstract translation: 一种具有芯片保持器，光源，角度调整单元，光传感器，滤光器保持器，激发截止滤光器，散射光透射单元，透射调节单元和控制单元的表面等离子体荧光分析装置 。 如平面图所示，散射光透射单元所占据的面积被布置在激发光截止滤光器上或滤光器支架上，并且比在平面图中看到的荧光发射区域的面积小。