Abstract:
PURPOSE: An antiviral composition containing fuco-oligosaccharides is provided to effectively suppress HSV-1 activation and to prevent and treat diseases caused by HSV-1 infection. CONSTITUTION: An antiviral composition for HSV(herpes simplex virus) contains fuco-oligocsaccharides as an active ingredient. The fuco oligosaccharides are prepared by decomposition of fucoidan extracted from Korean sea mustard. A pharmaceutical product for preventing or treating diseases caused by herpes simplex virus contains the antiviral composition as an active ingredient.
Abstract:
본 발명은 갈조류 유래의 푸코이단을 푸코 올리고당으로 분해할 수 있는 효소를 보유한 스핑고모나스( Sphingomonas ) 속 미생물, 상기 스핑고모나스 속 미생물을 푸코이단과 펩톤을 포함한 배지에서 pH를 5.0 내지 10.0으로 하고 염 농도를 0 내지 3%로 한 조건에서 배양하는 상기 스핑고모나스 속 미생물의 배양방법 및 상기 스핑고모나스 속 미생물과 푸코이단을 접하게 하여 푸코이단을 푸코 올리고당으로 분해하는 푸코 올리고당의 제조방법에 관한 것이다. 푸코 올리고당은 푸코이단 보다 더욱 탁월한 항혈전, 항암 및 항바이러스 효능을 발휘한다. 푸코이단, 푸코 올리고당, 스핑고모나스 속 미생물
Abstract:
PURPOSE: A pharmaceutical composition containing extract having antiviral activity, which is obtained from Phellinus pini is provided to suppress enzyme activity relating to viral infection mechanism and to prevent viral diseases. CONSTITUTION: A pharmaceutical composition for preventing or treating diseases by infection of coxsackievirus, influenza virus, or herpes simplex virus contains Phellinus pini-derived antiviral extract as an active ingredient. The extract is obtained from a fruit body of the Phellinus pini by adding polar solvent and centrifuging. The polar sovent is alcohol of 1-4 carbon atoms. The extract is contained in a concentration of 0.001-5.0 mg/ml. The extract contains water soluble polysaccharide of beta-(1,3)(1,6)-glucan.