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公开(公告)号：KR1020120118174A
公开(公告)日：2012-10-26
申请号：KR1020110035592
申请日：2011-04-18
Applicant: 강릉원주대학교산학협력단
IPC: A61K35/616 , A23L1/30
CPC classification number: A61K35/616 , A23L33/10
Abstract: PURPOSE: An antioxidant composition including stichopus extracts having anti-oxidant activity is provided to deactivate the active oxygen, thereby applying to all diseases related to the active oxygen. CONSTITUTION: An antioxidant composition includes stichopus extracts or fractions thereof. The Stichopus is a body wall or internal organs of the Stichopus. The Stichopus fractions is chloroform fraction, hexane fraction, ethylacetate fraction or butanol fraction. The concentration of the stichopus extracts or the fractions is 0.1-0.5 mg/mL. The Stichopus extracts or the fractions are obtained by the following steps: extracting by adding 80% methanol to stichopus and vacuumed drying thereof; dissolving the dried extract in water and partitioning thereof with chloroform; and vacuum drying the fractions.
Abstract translation: 目的：提供包含具有抗氧化活性的粪便提取物的抗氧化剂组合物以使活性氧失活，从而适用于与活性氧相关的所有疾病。 构成：抗氧化剂组合物包括刺槐提取物或其级分。 茎us属于茎a的体壁或内脏。 石蒜馏分是氯仿级分，己烷级分，乙酸乙酯级分或丁醇级分。 粪便提取物或级分的浓度为0.1-0.5mg / mL。 通过以下步骤获得油菜菌提取物或级分：通过向粪便中加入80％甲醇萃取并真空干燥; 将干燥的提取物溶解在水中并用氯仿分配; 并真空干燥级分。
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公开(公告)号：KR1020120113929A
公开(公告)日：2012-10-16
申请号：KR1020110031623
申请日：2011-04-06
Applicant: 강릉원주대학교산학협력단
IPC: A61K31/201 , A61K35/616 , A23L1/30
CPC classification number: A61K31/201 , A23L33/10 , A61K35/616
Abstract: PURPOSE: A pharmaceutical or food composition containing sea cucumber-derived compounds and a method for preparing the same are provided to treat or prevent diabetes without side effect. CONSTITUTION: A pharmaceutical composition for preventing or treating diabetes contains a compound of chemical formulas 1-4 as an active ingredient. The compound of chemical formula 1 or 2 is isolated from body wall of the sea cucumber and the compound of chemical formula 3 or 4 is isolated from intestine of sea cucumber. A method for preparing the sea cucumber extract comprises: a step of extracting sea cucumber with 80% methanol and drying the extract by vacuum; a step of dissolving the dried extract with water and fractioning with hexane; and a step of drying the fraction by vacuum. The extract contains the compounds of chemical formulas 1-4.
Abstract translation: 目的：提供含有海参衍生化合物的药物或食品组合物及其制备方法，用于治疗或预防糖尿病而无副作用。 构成：用于预防或治疗糖尿病的药物组合物含有化学式1-4化合物作为活性成分。 化学式1或化合物2的化合物与海参的体壁分离，化学式3或4的化合物从海参肠中分离出来。 一种制备海参提取物的方法，包括：用80％甲醇萃取海参，真空干燥提取物的步骤; 将干燥的提取物用水溶解并用己烷分馏的步骤; 以及通过真空干燥级分的步骤。 提取物含有化学式1-4的化合物。
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公开(公告)号：KR1020100134257A
公开(公告)日：2010-12-23
申请号：KR1020090052783
申请日：2009-06-15
Applicant: 강릉원주대학교산학협력단
IPC: A61K35/618 , A61K38/46 , A23L17/50 , A23L33/00
CPC classification number: A61K35/618 , A23L17/50 , A23L33/00 , A61K38/46
Abstract: PURPOSE: A composition for reducing cholesterol by zymolysis of squid is provided to decompose squid in a peptide of low molecule and to reduce blood cholesterol. CONSTITUTION: A composition for reducing cholesterol contains enzyme lysate of squid a main ingredient. The enzyme lysate of squid is obtained by hydrolysate of squid using an enzyme. A pharmaceutical composition for reducing cholesterol contains the composition and pharmaceutically acceptable excipient. A health food composition for reducing cholesterol contains the composition and sitologically acceptable excipient.
Abstract translation: 目的：提供一种通过鱿鱼的酶解降低胆固醇的组合物，用于分解低分子肽中的鱿鱼并降低血液胆固醇。 构成：用于降低胆固醇的组合物含有鱿鱼的酶裂解物作为主要成分。 鱿鱼的酶裂解物通过使用酶水解鱿鱼得到。 用于降低胆固醇的药物组合物含有组合物和药学上可接受的赋形剂。 用于降低胆固醇的保健食品组合物含有组合物和可以使用的可接受的赋形剂。
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公开(公告)号：KR100991882B1
公开(公告)日：2010-11-04
申请号：KR1020080044450
申请日：2008-05-14
Applicant: 강릉원주대학교산학협력단 , 강원도립대학교산학협력단
Abstract: 본 발명은 오징어 내장의 발효생성물을 이용한 천연 조미료 및 이의 제조방법에 관한 것이다. 본 발명에 따르면 오징어 건조 및 조미제품 제조시 부산물로 파생되는 오징어 내장을 새로운 식품가공 소재로 이용함으로써 원가를 절감할 수 있으며, 제품화된 오징어 조미료는 화학조미료를 대신할 수 있는 우수한 효과가 있다. 또한 본 발명은 오징어 내장뿐만 아니라 모든 수산가공 부산물의 활용에도 응용될 수 있다.
오징어, 내장, 발효생성물, 천연조미료-
公开(公告)号：KR1020090118578A
公开(公告)日：2009-11-18
申请号：KR1020080044451
申请日：2008-05-14
Applicant: 강릉원주대학교산학협력단 , 강원도립대학교산학협력단
Abstract: PURPOSE: A natural seasoning using cuttlefish internal organs and a preparation method thereof are provided to replace a chemical seasoning to improve consumer preference. CONSTITUTION: A method for preparing a natural seasoning using cuttlefish internal organs comprises the following steps of: washing cuttlefish internal organs and dehydrating them; grinding the cuttlefish internal organs; mixing water, koji, salt, and ground cuttlefish internal organs at a ratio of 0.3:0.05:0.05-0.15:1; fermenting the mixture at 17~23°C for 2-5 weeks; sterilizing the mixture at 100°C for 10 minutes, and freeze-drying and grinding the mixture; and mixing the 30g mixture, 5-20g salt, 5g nucleic acid, 10g glucose, 5g red pepper powder, 3g soybean paste powder, 1g onion powder, 0.5g ginger powder, and 2g garlic powder.
Abstract translation: 目的：提供使用墨鱼内脏的天然调味料及其制备方法，以取代化学调味料以改善消费者偏好。 构成：使用墨鱼内脏制备天然调味料的方法包括：清洗乌贼内脏，脱水; 研磨墨鱼内脏; 以0.3：0.05：0.05-0.15：1的比例混合水，曲，盐和地鳖鱼内脏; 在17〜23℃下将混合物发酵2-5周; 将混合物在100℃下灭菌10分钟，并冷冻干燥并研磨该混合物; 混合30g混合物，5-20g盐，5g核酸，10g葡萄糖，5g红辣椒粉，3g大豆酱粉，1g洋葱粉，0.5g姜粉和2g大蒜粉。
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Patent Agency Ranking
公开(公告)号：KR1020070101924A
公开(公告)日：2007-10-18
申请号：KR1020060033356
申请日：2006-04-12
Applicant: 강릉원주대학교산학협력단
IPC: C12N9/36
Abstract: A lysozyme derived from Scallop(Patinopecten yessoensis) viscera is provided to actively inhibit growth of both gram-positive and gram-negative bacteria such as Escherichia coli and Vibrio vulnificus at relatively low temperature and low hydrogen concentration. A lysozyme is isolated and purified from Scallop(Patinopecten yessoensis) viscera through affinity chromatography and has characteristic properties of molecular weight of 14.3 kDa, optimal temperature of 20-30 deg.C, optimal pH of 5.0 and optimal stability pH of 5.0-6.0 and excellent antibacterial activity against gram-negative bacteria including Escherichia coli and Vibrio vulnificus.
Abstract translation: 提供来自扇贝（Patinopecten yessoensis）内脏的溶菌酶，以在相对较低的温度和低的氢浓度下主动抑制革兰氏阳性和革兰氏阴性细菌如大肠杆菌和创伤弧菌的生长。 通过亲和层析从扇贝（Patinopecten yessoensis）内脏中分离纯化溶菌酶，分子量为14.3 kDa，最适温度为20-30℃，最佳pH为5.0，最佳pH为5.0-6.0， 对革兰氏阴性细菌（包括大肠杆菌和创伤弧菌）具有优异的抗菌活性。
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公开(公告)号：KR101505294B1
公开(公告)日：2015-03-23
申请号：KR1020130070488
申请日：2013-06-19
Applicant: 강릉원주대학교산학협력단
IPC: A61K35/616 , A61K8/98 , A61Q19/00
Abstract: 본 발명은 불가사리 부화액 추출물에서 분리 및 정제한 신규한 부화 효소에 관한 것으로, 더욱 구체적으로는 상기 불가사리 부화 효소의 효소 역가를 확인하고, 효소의 최대 역가 조건을 수립하였으며, 상기 효소가 켈로이드 또는 흉터의 원인이 되는 타입 Ⅰ 콜라겐의 가수분해 역가를 가지므로, 켈로이드 또는 흉터의 치료 또는 예방용 화장료 조성물로 이용 가능한 효과가 있다.
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公开(公告)号：KR101262743B1
公开(公告)日：2013-05-09
申请号：KR1020110031623
申请日：2011-04-06
Applicant: 강릉원주대학교산학협력단
IPC: A61K31/201 , A61K35/616 , A23L1/30
Abstract: 본발명은해삼유래하기화학식 1 내지화학식 4를유효성분으로포함하는당뇨병예방또는치료용약학조성물, 식품조성물및 이의제조방법에관한것이다. 본발명의해삼추출물또는분획물은α-glucosidase 저해활성을갖고있으므로당뇨병치료또는예방효과가있을뿐만아니라, 천연물질인해삼추출물을포함하고있으므로, 부작용등이문제되지않는다.
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19.发明公开미세조류 유래 색소를 추출하는 방법 및 추출된 푸코크산틴을 포함하는 비만 또는 당뇨의 예방 또는 치료용 조성물 有权提取微胶囊细胞色素的方法和包含提取的福莫西汀的组合物，用于预防或治疗肥胖或糖尿病
公开(公告)号：KR1020120137091A
公开(公告)日：2012-12-20
申请号：KR1020110056413
申请日：2011-06-10
Applicant: 강릉원주대학교산학협력단
Abstract: PURPOSE: A method for extracting pigment from microalgae and a composition containing fucoxanthin for preventing or treating obesity or diabetes are provided to enhance stability. CONSTITUTION: A method for extracting pigment from microalgae comprises a step of performing accelerated solvent extraction using 10-100% ethanol at 0-1,500 psi and 40-160 Deg.C. for 1-30 minutes. The microalgae include Chlorophyte, Phaeophyceae, Rhodophyte, Cyanophyta, Bacillariophycea, Dinophyta, or Haptophyta. The pigment is fucoxanthin. A pharmaceutical composition for preventing or treating obesity or diabetes contains fucoxanthin.
Abstract translation: 目的：提供从微藻中提取色素的方法和含有岩藻黄质的组合物，用于预防或治疗肥胖或糖尿病，以提高稳定性。 构成：从微藻提取颜料的方法包括使用10-100％乙醇在0-1,500psi和40-160℃下进行加速溶剂萃取的步骤。 持续1-30分钟。 微藻包括Chlorophyte，Phaeophyceae，Rhodophyte，Cyanophyta，Bacillariophycea，Dinophyta或Haptophyta。 颜料是岩藻黄素。 用于预防或治疗肥胖症或糖尿病的药物组合物含有岩藻黄素。
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公开(公告)号：KR101178860B1
公开(公告)日：2012-08-31
申请号：KR1020110048092
申请日：2011-05-20
Applicant: 강릉원주대학교산학협력단
Abstract: PURPOSE: Natural seasonings including microalgae protein hydrolysate, and a producing method thereof are provided to improve the protein-dissolving capacity of microalgae before hydrolyzing the microalgae. CONSTITUTION: A producing method of natural seasonings including microalgae protein hydrolysate comprises the following steps: processing chlorella vulgaris or tetraselmis suecica with ultrasonic waves using an ultrasonic generator in the frequency of 90-100kHz for 4-5 hours for eluting protein; and producing the protein hydrolysate by hydrolyzing the protein for 50-60 minutes using proteinase in the pH of 6-7. The proteinase is alcalase.
Abstract translation: 目的：提供微藻蛋白水解产物的天然调味料及其生产方法，以提高微藻水解微藻的蛋白质溶解能力。 构成：微藻蛋白水解产物的天然调味料的生产方法包括以下步骤：使用超声波发生器，以90-100kHz的频率处理小球藻或四孢子虫，4-5小时洗脱蛋白质; 并通过使用蛋白酶在6-7的pH下水解蛋白质50-60分钟来生产蛋白质水解产物。 蛋白酶是alcalase。
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