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公开(公告)号：KR1020110015197A
公开(公告)日：2011-02-15
申请号：KR1020090072793
申请日：2009-08-07
Applicant: 고려대학교 산학협력단
IPC: A61K9/16 , A61K31/165 , A61P19/00
CPC classification number: A61K9/5192 , A61K9/5161 , A61K31/165
Abstract: PURPOSE: A sustained release therapeutic agent for treating disk diseases containing biodegradable polymer nanoparticles and a method for manufacturing the same are provided to selectively remove painful nerve of dorsal root ganglia. CONSTITUTION: A sustained release therapeutic agent for treating disk diseases contains biodegradable polymer nanoparticles. The biodegradable nanoparticles are polylactic acid(PLLA), polylactic-glycolic copolymer(PLGA) polycarpropactan(PCL), polyglycolic acid(PGA), polylactic-caprolactan copolymer(PLCL) or polyglycolic-caprolactan copolymer(PGCL). The therapeutic agent further contains fibrin. A method for manufacturing the therapeutic agent comprises: a step of mixing a first solution containing biodegradable polymers, capsaicin and organic solvent and a second solution containing PVA(polyvinyl alcohol) and soluble solvent; a step of treating by ultrasonication to form oil-in-water emulsion; and a step of removing the organic solvent from the emulsion.
Abstract translation: 目的：提供一种用于治疗包含可生物降解的聚合物纳米颗粒的盘状疾病的缓释治疗剂及其制造方法，以选择性地去除背根神经节的疼痛神经。 构成：用于治疗椎间盘疾病的缓释治疗剂包含可生物降解的聚合物纳米颗粒。 可生物降解的纳米颗粒是聚乳酸（PLLA），聚乳酸 - 乙交酯共聚物（PLGA）聚丙交酯（PCL），聚乙醇酸（PGA），聚乳酸 - 己内酰胺共聚物（PLCL）或聚乙醇酸 - 己内酰胺共聚物（PGCL）。 治疗剂还含有纤维蛋白。 制造治疗剂的方法包括：将含有可生物降解的聚合物的第一溶液，辣椒素和有机溶剂与含有PVA（聚乙烯醇）和可溶性溶剂的第二溶液混合的步骤; 通过超声波处理形成水包油乳液的步骤; 以及从乳液中除去有机溶剂的步骤。
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公开(公告)号：KR102245306B1
公开(公告)日：2021-04-29
申请号：KR1020190060520
申请日：2019-05-23
Applicant: 고려대학교 산학협력단
IPC: A61B17/32 , A61B17/3207 , A61B17/00
Abstract: 본발명은선택적탈출부위제거장치에관한것으로서, 손잡이및 작동버튼을구비하는몸체; 일방향을따라연장되는중공의관 형상으로형성되어몸체의일단에서연통되도록결합되는가이드; 가이드의종단에결합되어연부조직을절삭하는연화구를구비하는파쇄부; 및일단이연화구에인접하고타단이가이드의내부를따라배치되면서몸체의바깥으로돌출되어연화구를통해절삭된연부조직을포집하는포집부;를포함한다.
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公开(公告)号：KR101892243B1
公开(公告)日：2018-08-27
申请号：KR1020160089604
申请日：2016-07-15
Applicant: 고려대학교 산학협력단 , 주식회사 한라 , 에이치디씨현대산업개발 주식회사
CPC classification number: E04G21/3247 , E04G3/00 , E04G3/28 , E04G21/00 , E04G2003/283
Abstract: 본발명은, 건축물의골조공사를시공하기위하여베이스발판을지지하는베이스프레임을포함하는케이지베이스(20)를구비하는건축용케이지장치로서, 상기케이지베이스에상대가동가능하게배치되어건축물의외장공사를시공가능하는케이지곤돌라유니트(30)를포함하는건축용케이지장치를제공한다.
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公开(公告)号：KR1020130051170A
公开(公告)日：2013-05-20
申请号：KR1020110116363
申请日：2011-11-09
Applicant: 부산대학교 산학협력단 , 고려대학교 산학협력단
CPC classification number: A61B17/3401 , A61B2017/00535 , A61B2017/00862
Abstract: PURPOSE: A needle for the backbone rearward nerve blocking is provided to form an inclined surface between a lead hole and a penetration unit of an outer needle in an arc, thereby minimizing the resistance of withdraws of an inner needle by minimizing the contact with the inner needle. CONSTITUTION: An inner needle(200) is withdrawn by being inserted to a penetration unit(110) of an outer needle. A lead hole(120) is formed in the end of the penetration unit. An inclined surface(130) which is inclined to the lead hole is formed between the lead hole and penetration unit. The inclined surface is formed in the arc and minimizes the contact with the inner needle. In the outer needle, a sleeve(140) is equipped. In the inner needle, a plunger(220) which is inserted into the sleeve is equipped.
Abstract translation: 目的：提供用于脊柱后神经阻塞的针，以在电弧中的引线孔和外针的穿透单元之间形成倾斜表面，从而通过最小化与内部接触的内针的退回阻力来最小化 针。 构成：内针（200）通过插入到外针的穿透单元（110）中而被抽出。 在穿透单元的端部形成有引线孔（120）。 在引导孔和穿透单元之间形成有与引线孔倾斜的倾斜面（130）。 倾斜表面形成在弧中并使与内针的接触最小化。 在外针中，配备有套筒（140）。 在内针中插入插入套筒的柱塞（220）。
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Patent Agency Ranking
公开(公告)号：KR1020110056803A
公开(公告)日：2011-05-31
申请号：KR1020090113275
申请日：2009-11-23
Applicant: 고려대학교 산학협력단
CPC classification number: Y02E60/128 , H01M4/86 , H01M4/88 , H01M12/08
Abstract: PURPOSE: An air electrode for a metal-air secondary battery is provided to realize oxygen reduction and oxygen evolution as a catalyst and to enable reversible charging/discharging. CONSTITUTION: A method for preparing an air electrode for a metal-air secondary battery comprises the steps of: wet injecting La(NO3)36H2O into a platinum-loaded gas diffusion electrode; drying the gas diffusion electrode to which lanthanum(La) is injected in a vacuum atmosphere; and drying the gas diffusion electrode at 200-250 °C for 3 hours in an atmospheric condition.
Abstract translation: 目的：提供一种用于金属 - 空气二次电池的空气电极，以实现作为催化剂的氧还原和氧气逸出，并实现可逆充电/放电。 构成：用于制备金属 - 空气二次电池的空气极的方法包括以下步骤：将La（NO 3）3·6H 2 O湿法注入负载铂的气体扩散电极; 干燥在真空气氛中注入镧（La）的气体扩散电极; 并在大气条件下在200-250℃下干燥气体扩散电极3小时。
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公开(公告)号：KR101044599B1
公开(公告)日：2011-06-29
申请号：KR1020090072792
申请日：2009-08-07
Applicant: 고려대학교 산학협력단
Abstract: 본 발명은 말단에 광가교결합 가능한 작용기를 갖는 수용성의 생체적합성 중합체를 가교결합시켜 제조된 온도변화에 따라 직경이 변화하는 온도민감성 나노운반체 및 상기 나노운반체 내에 포함된 카이모파파인(chymopapain)을 포함하는 것을 특징으로 하는 추간판용 서방성 치료제 및 이의 제조방법에 관한 것이다.
카이모파파인, 나노운반체-
公开(公告)号：KR1020110015196A
公开(公告)日：2011-02-15
申请号：KR1020090072792
申请日：2009-08-07
Applicant: 고려대학교 산학협력단
CPC classification number: A61K38/4873 , A61K9/0002 , A61K9/1641 , A61K47/34 , B82Y5/00
Abstract: PURPOSE: A sustained release therapeutic agent for an intervertebral disc containing temperature-sensitive nano-carriers and chymopapain and a method for manufacturing the same are provided to preserve normal disc. CONSTITUTION: A sustained release therapeutic agent for an intervertebral disc contains: temperature-sensitive nano-carriers which is obtained by cross-linking soluble biocompatible polymers having a photo-crosslinkable functional group and chemopapain contained in the nano-carrier. The functional group is acrylate, diacrylate, oligoacrylate, methacrylate, dimethacylate, oligomethacrylate, coumarin, thyamine or cinnamate.
Abstract translation: 目的：提供用于含有温度敏感性纳米载体和木瓜凝乳蛋白酶的椎间盘的缓释治疗剂及其制造方法以保持正常的椎间盘。 构成：用于椎间盘的持续释放治疗剂包含：通过交联具有光可交联官能团的可溶性生物相容性聚合物和包含在纳米载体中的化学发光蛋白得到的温度敏感性纳米载体。 官能团为丙烯酸酯，二丙烯酸酯，低聚丙烯酸酯，甲基丙烯酸酯，二甲基丙烯酸酯，低聚甲基丙烯酸酯，香豆素，甲胺或肉桂酸酯。
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公开(公告)号：KR1020090101731A
公开(公告)日：2009-09-29
申请号：KR1020080027043
申请日：2008-03-24
Applicant: 고려대학교 산학협력단
Abstract: PURPOSE: A microwave electrode apparatus is provided, which enables to make high frequency accurately reach the body tissue in which the surgical operation is required. CONSTITUTION: A microwave electrode apparatus includes a first tube, a first electrode pair, a first steel wire, and a second steel wire. The first tube(110) is connected to a manipulator and has the length that can be inserted into the body structure. The high frequency is applied to the first electrode pair(120) which is formed in the first side end of the first tube. The first and second steel wires are connected to the manipulator through the first electrode pair and the first tube.
Abstract translation: 目的：提供一种微波电极装置，其能够使高频精确地到达需要外科手术的身体组织。 构成：微波电极装置包括第一管，第一电极对，第一钢丝和第二钢丝。 第一管（110）连接到操纵器并且具有可插入体结构的长度。 高频被施加到形成在第一管的第一侧端的第一电极对（120）。 第一和第二钢丝通过第一电极对和第一管连接到操纵器。
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公开(公告)号：KR100802148B1
公开(公告)日：2008-02-11
申请号：KR1020060131578
申请日：2006-12-21
Applicant: 고려대학교 산학협력단 , 유앤아이 주식회사
Abstract: A radio frequency ablation electrode for selected tissue removal is provided to easily cut through obstructed hard fiber to easily perform an operation for a patient long troubled with disc herniation. A radio frequency ablation electrode(100) for selected tissue removal includes a first electrode(110), a second electrode(120), a first electrode tip(112), and a second electrode tip(122). The first and second electrodes are inserted into a tissue. The first electrode tip is formed on an end of the first electrode and the second electrode tip is formed on an end of the second electrode. The first and second electrode tips are spaced apart from each other at a predetermined interval. A coil spring is connected to end portions of the first and second electrode. The coil spring has an end portion in a bent shape in a free state. The coil spring is transformed by pulling at least one of the first and second electrodes.
Abstract translation: 提供用于选择组织去除的射频消融电极，以容易地切割阻塞的硬纤维，以容易地进行长期与椎间盘突出症相关的患者的手术。 用于选择的组织去除的射频消融电极（100）包括第一电极（110），第二电极（120），第一电极尖端（112）和第二电极尖端（122）。 将第一和第二电极插入组织中。 第一电极尖端形成在第一电极的端部上，并且第二电极尖端形成在第二电极的端部上。 第一和第二电极头以预定的间隔相互间隔开。 螺旋弹簧连接到第一和第二电极的端部。 螺旋弹簧具有处于自由状态的弯曲形状的端部。 通过拉动第一和第二电极中的至少一个来转换螺旋弹簧。
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