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公开(公告)号：KR1020090099974A
公开(公告)日：2009-09-23
申请号：KR1020080025297
申请日：2008-03-19
Applicant: 대구한의대학교산학협력단
IPC: A61K36/605 , A61P3/06 , A61P3/04
CPC classification number: A61K36/605 , A23V2200/326 , A23V2200/3262 , A61K2236/331 , A61K2236/333 , Y10S514/909
Abstract: PURPOSE: A composition for preventing or treating hyperlipidemia or obesity, which contains extract of Morus alba L. leaves is provided to reduce the content of total blood cholesterol, triglyceride, LDL-cholesterol, weight, lipid and blood leptin. CONSTITUTION: A pharmaceutical composition for preventing and treating hyperlipidermia or obesity contains extract of Morus alba L. leaves as an active ingredient. The extract is isolated using water including purified water, low alcohol of 1-4 carbon atoms or their mixture solvent.
Abstract translation: 目的：提供一种预防或治疗高脂血症或肥胖症的组合物，其含有桑叶叶提取物以降低总胆固醇，甘油三酯，低密度脂蛋白胆固醇，体重，脂质和血液瘦素的含量。 构成：用于预防和治疗高脂血症或肥胖症的药物组合物含有桑叶叶提取物作为活性成分。 使用纯净水，1-4碳原子的低级醇或其混合溶剂的水分离提取物。
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12.发明公开
公开(公告)号：KR1020170001209A
公开(公告)日：2017-01-04
申请号：KR1020150090881
申请日：2015-06-26
Applicant: 대구한의대학교산학협력단
Abstract: 본발명은밀몽화추출물을유효성분으로함유하는간질환의예방또는치료용조성물에관한것으로, 본발명의밀몽화추출물은미토콘드리아보호작용을통한간세포보호효과가우수하고, 간보호작용을보이며정상세포에독성을유발하지않는다는것을확인함으로써, 간질환치료제또는간질환예방을위한건강기능성식품의유효성분으로사용할수 있다.
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公开(公告)号：KR101146861B1
公开(公告)日：2012-05-16
申请号：KR1020100000817
申请日：2010-01-06
Applicant: 대구한의대학교산학협력단
Abstract: PURPOSE: A composition containing Statholobi Caulis extract is provided to reduce H4IIE cytotoxicity induced by cadmium and to protect liver. CONSTITUTION: A pharmaceutical composition for preventing and treating liver disease contains Statholobi Caulis extract as an active ingredient. The Statholobi Caulis extract is a soluble in water including purified water, low alcohol of C1-C4, or mixture solvent thereof. A health food for preventing and treating alcoholic liver diseases contains Statholobi Caulis extract as an active ingredient. The health food is used in the form of powder, granule, tablet, capsule, or beverage.
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公开(公告)号：KR1020110120633A
公开(公告)日：2011-11-04
申请号：KR1020100040121
申请日：2010-04-29
Applicant: 대구한의대학교산학협력단
IPC: A23L19/00
CPC classification number: A23L19/00 , A23V2250/21 , A23V2300/14 , A23V2300/24 , A23V2300/50
Abstract: PURPOSE: A processing method of glycyrrhizae radix having the increased content of liquiritigenin is provided to secure an optimal analysis condition for the liquiritigenin from a glycyrrhizae radix extract. CONSTITUTION: A processing method of glycyrrhizae radix having the increased content of liquiritigenin comprises the following steps: processing the glycyrrhizae radix by heating at 150-400 deg C for 1-20 minutes, by acidifying using a weak acid and alcohol mixed solution, or by combining both processes regardless of the order; extracting the glycyrrhizae radix at 0-100 deg C for 1-10 hours using a maceration extraction method, a hot water extraction method, an ultrasonic extraction method, a reflux cooling extraction method, or a heating extraction method for 1-7 times; and filtering and decompress-concentrating the extract to obtain a glycyrrhizae radix extract.
Abstract translation: 目的：提供甘草素含量增加的甘草碱的加工方法，以确保甘草提取物中甘草素的最佳分析条件。 构成：甘草素含量增加的甘草碱的加工方法包括以下步骤：通过在150-400℃加热1-20分钟，通过使用弱酸和醇混合溶液酸化或通过使用弱酸和醇混合溶液进行酸化来加工甘草 无论订单如何组合两个进程; 使用浸提法，热水提取法，超声提取法，回流冷却提取法或加热提取法，在0-100℃下将甘草提取1-10小时; 并对提取物进行过滤和减压浓缩，得到甘草提取物。
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公开(公告)号：KR101059359B1
公开(公告)日：2011-08-24
申请号：KR1020080068176
申请日：2008-07-14
Applicant: 대구한의대학교산학협력단
IPC: A61K36/505
CPC classification number: Y02A50/473
Abstract: 본 발명은 약효가 증강된 현호색 추출물, 그 제조방법 및 그를 함유하는 항균용 조성물에 관한 것으로, 상세하게는 본 발명의 제조방법에 의해 수득된 현호색 추출물은 유효성분인 디하이드로코리달린(dehydrocorydaline)의 함량이 증강되어 여드름의 원인균인
P.
acnes (
Propionibacterium
acnes ) 및 충치의 원인균인 S.
mutans (
Streptococci
mutans )에 대한 증진된 항균 활성을 가지고 있으므로, 충치 및 여드름의 예방 및 치료에 유용하게 이용될 수 있다.
현호색, 디하이드로코리달린, 충치, 여드름Abstract translation: 本发明涉及一种用于药物的抗微生物组合物增强的延胡索提取物，用（dehydrocorydaline）由本发明的制造方法得到的活性成分制造方法，以及含有它们中，特别的二氢科里的延胡索提取物的方法 痤疮引起致病菌的含量增加
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Patent Agency Ranking16.发明公开현호색 추출물 또는 이로부터 분리되는디하이드로코리달린을 유효성분으로 함유하는 여드름의개선 및 치료용 조성물 无效包含用于治疗和改善ACNE VULGARIS的CORYDALIS TURTSCHANINOVII或脱氢赖氨酸分离物的提取物的组合物
公开(公告)号：KR1020090055243A
公开(公告)日：2009-06-02
申请号：KR1020070122065
申请日：2007-11-28
Applicant: 대구한의대학교산학협력단
IPC: A61K8/97 , A61Q19/00 , A61K36/505 , A61P17/10
Abstract: A composition for improving and treating acne vulgaris, which contains Corydalis turtschaninovii extract or dehydrocorydaline is provided to have antibacterial effect against propionibacterium acnes. A pharmaceutical composition of skin external preparation for improving and treating acne vulgaris comprises 0.1-50 weight% of Corydalis turtschaninovii extract or dehydrocorydaline as an active ingredient. The Corydalis turtschaninovii extract is isolated from stem, leaf, and flower of Corydalis Tuber using one or more solvent selected from water, ethanol, methanol, propanol, butanol, acetone, ethylacetate, hexane, butylenes glycol, propylene glycol and hydrous butylenes glycol, hydrous propylene glycol and hydrous glycerin. The composition is used in a form of cream, gel, patch, ointment, lotion, or cataplasma agent.
Abstract translation: 提供一种用于改善和治疗寻常痤疮的组合物，其含有延胡索提取物或脱氢卡氨酸，以对痤疮丙酸杆菌具有抗菌作用。 用于改善和治疗寻常痤疮的皮肤外用制剂的药物组合物包含0.1-50重量％的延胡索提取物或脱氢卡氨酸作为活性成分。 使用一种或多种选自水，乙醇，甲醇，丙醇，丁醇，丙酮，乙酸乙酯，己烷，丁二醇，丙二醇和含水丁二烯二醇的溶剂，分离出紫茎泽兰提取物的茎，叶和花。 丙二醇和含水甘油。 组合物以霜剂，凝胶剂，贴剂，软膏剂，洗剂或粘膜剂的形式使用。
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公开(公告)号：KR1020170023405A
公开(公告)日：2017-03-03
申请号：KR1020170022274
申请日：2017-02-20
Applicant: 대구한의대학교산학협력단
IPC: A61K36/73 , A23L33/105
Abstract: 본발명은매괴화추출물을유효성분으로함유하는간질환의예방또는치료용조성물에관한것으로, 본발명의매괴화추출물은간세포손상시 증가하는형질전환성장인자베타1(TGF-β1)에의한 Smad 분자의인산화를억제하는효과가우수하고정상세포에독성을유발하지않는다는것을확인함으로써, 간질환치료제또는간질환예방을위한건강기능성식품의유효성분으로사용할수 있다.
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公开(公告)号：KR1020170000151A
公开(公告)日：2017-01-02
申请号：KR1020150088991
申请日：2015-06-23
Applicant: 대구한의대학교산학협력단
Abstract: 본발명은부평초추출물을유효성분으로함유하는간질환의예방또는치료용조성물에관한것으로, 본발명의부평초추출물은미토콘드리아보호작용을통한간세포보호효과가우수하고, 간보호작용을보이며정상세포에독성을유발하지않는다는것을확인함으로써, 간질환치료제또는간질환예방을위한건강기능성식품의유효성분으로사용할수 있다.
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公开(公告)号：KR1020160142713A
公开(公告)日：2016-12-13
申请号：KR1020150078800
申请日：2015-06-03
Applicant: 대구한의대학교산학협력단
IPC: A61K36/282 , A23L1/30
Abstract: 본발명은청호추출물을유효성분으로함유하는간질환의예방또는치료용조성물에관한것으로, 본발명의청호추출물은 AMPK pathway 활성화및 미토콘드리아보호작용을통한간세포보호효과가우수하고, 간보호작용을보이며정상세포에독성을유발하지않는다는것을확인함으로써, 간질환치료제또는간질환예방을위한건강기능성식품의유효성분으로사용할수 있다.
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公开(公告)号：KR101215797B1
公开(公告)日：2012-12-26
申请号：KR1020100104019
申请日：2010-10-25
Applicant: 대구한의대학교산학협력단
Abstract: 본발명은뽕나무추출물을유효성분으로함유하는조성물에관한것으로서, 더욱상세하게는본 발명의뽕나무추출물이만성적인간세포손상시 증가하는형질전환성장인자베타1(TGF-&bgr;1)에의한 Smad 분자의인산화에대한억제효과를나타냄으로써, 간경화(경화성간질환)증의예방및 치료용약학조성물또는건강기능식품으로유용하게이용될수 있다.
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