公开(公告)号：KR100460685B1

公开(公告)日：2004-12-09

申请号：KR1020020019520

申请日：2002-04-10

Applicant: 재단법인서울대학교산학협력재단

Inventor： 유현승 ,  홍국선 ,  이춘기 ,  이동호 ,  이상림 ,  장봉순 ,  김수진 ,  임창균

IPC: A61L27/12

CPC classification number: A61L27/12 ,  A61F2/4644 ,  A61F2002/2835 ,  A61F2310/00293 ,  A61L27/56 ,  A61L2430/02

Abstract: A bone graft substitute using magnesium substituted calcium phosphate compounds and a method of manufacturing the same is provided in which the bone graft substitute is used for recovering bones damaged due to a bone fracture. The method of manufacturing a bone graft substitute includes the steps of mixing powdered calcium pyrophosphate and a magnesium included compound to thereby obtain a composition, pressure-forming the compositions to obtain a plastic body; and sintering the plastic body.

Abstract translation: 提供了使用镁取代磷酸钙化合物的骨移植替代物及其制造方法，其中骨移植替代物用于恢复由于骨折而损坏的骨。 制造骨移植替代品的方法包括以下步骤：将粉状焦磷酸钙和含镁化合物混合，从而获得组合物，将组合物加压成形以获得塑性体; 并烧结塑料体。

公开(公告)号：KR100496458B1

公开(公告)日：2005-06-23

申请号：KR1020020052566

申请日：2002-09-02

Applicant: 재단법인서울대학교산학협력재단

Inventor： 유현승 ,  홍국선 ,  김환 ,  이동호 ,  이춘기 ,  장봉순 ,  김득중 ,  서준혁 ,  이재협 ,  박기수

IPC: A61L27/10

CPC classification number: C03C4/0007 ,  A61L27/10 ,  A61L27/58 ,  C03C3/064 ,  C03C3/112 ,  C03C4/0014 ,  C03C8/22 ,  C03C10/00 ,  C03C11/00 ,  C03C12/00

Abstract: 본 발명은 생분해 속도가 늦은 결정화 유리와 생분해 속도가 빠른 결정화 유리를 복합 조성함으로써 생체 활성을 유지하면서 생체 분해 속도가 복합 비율에 따라 조절되는 결정화 유리에 관한 것이다.
본 발명은 산화칼슘(CaO), 실리카(SiO
2 ), 산화붕소(B
2 O
3 ), 산화마그네슘(MgO), 불화칼슘(CaF
2 ), 오산화인(P
2 O
5 )으로 조성된 것을 특징으로 하는 생체 흡수형 생체 활성 결정화 유리를 제공한다.

公开(公告)号：KR100465984B1

公开(公告)日：2005-01-17

申请号：KR1020020045175

申请日：2002-07-31

Applicant: 재단법인서울대학교산학협력재단

Inventor： 유현승 ,  홍국선 ,  이춘기 ,  이동호 ,  이재협 ,  장봉순 ,  김수진 ,  정성수

IPC: A61L27/10

Abstract: PURPOSE: Provided are a bio-active ceramics and a metallic implant used in surgical and dental applications coated with the ceramics in order to increase bio-affinity to a subject having the implant. CONSTITUTION: The bio-active ceramics comprises 40-49 wt.% of CaO, 40-49 wt.% of silica(SiO2) and 2-20 wt.% of B2O3. The process for producing the metallic implant comprises steps of preparing the bio-active ceramic by fusing raw material consisting of CaO, SiO2, B2O3 and quenching the fused material; grinding the frozen material into powders having less than 10 micrometer size; preparing slurry by adding aqueous or organic solvents and a binder; applying the slurry to a metallic implant by means of brush; and sintering the coated implant at 700-950 deg.C.

Abstract translation: 目的：提供一种生物活性陶瓷和金属植入物，其用于外科和牙科应用中涂覆有陶瓷以增加具有植入物的对象的生物亲和力。 构成：生物活性陶瓷包含40-49重量％的CaO，40-49重量％的二氧化硅（SiO2）和2-20重量％的B2O3。 生产金属植入物的方法包括以下步骤：通过熔化由CaO，SiO2，B2O3组成的原材料并淬火熔融材料来制备生物活性陶瓷; 将冷冻材料研磨成小于10微米大小的粉末; 通过加入水溶液或有机溶剂和粘合剂制备浆液; 通过刷子将浆料施加到金属植入物上; 并在700-950℃下烧结涂覆的植入物。

公开(公告)号：KR1020040019637A

公开(公告)日：2004-03-06

申请号：KR1020020051243

申请日：2002-08-28

Applicant: 재단법인서울대학교산학협력재단

Inventor： 유현승 ,  홍국선 ,  김환 ,  이동호 ,  이춘기 ,  장봉순 ,  김득중 ,  서준혁 ,  이재협 ,  박기수

IPC: C04B38/00 ,  C03C10/04 ,  A61L27/00

CPC classification number: C03C11/00

Abstract: PURPOSE: Provided is a simple manufacturing method of porous ceramics with high porosity, strength and softness by using the composition containing self-foaming inorganic constituents instead of adding a gas-foaming polymer through conventional ceramic process. CONSTITUTION: The self-foaming type porous ceramic composition contains calcium oxide(CaO), silica(SiO2), and borate(B2O3) self-foamed automatically at high temperature in a molar ratio of 43-47 : 43-47 : 6-14. The porous ceramics are manufactured by preparing glass comprising the above components, grinding into a size of 1-10micrometer, forming and thermal treating at 950-1200deg.C. The resultant ceramics are applied to heat insulating materials, catalyst carriers and artificial bones.

Abstract translation: 目的：通过使用含有自发泡性无机成分的组合物代替通过常规陶瓷工艺添加气泡聚合物，提供了具有高孔隙率，强度和柔软度的多孔陶瓷的简单制造方法。 构成：自发泡型多孔陶瓷组合物含有氧化钙（CaO），二氧化硅（SiO 2）和硼酸盐（B 2 O 3），其自身在高温下自发发泡，摩尔比为43-47:43-47:6-14 。 多孔陶瓷通过制备包含上述组分的玻璃制成，研磨成1-10微米的尺寸，在950-1200℃下进行热处理。 将所得的陶瓷应用于隔热材料，催化剂载体和人造骨。

公开(公告)号：KR1020040021111A

公开(公告)日：2004-03-10

申请号：KR1020020052566

申请日：2002-09-02

Applicant: 재단법인서울대학교산학협력재단

Inventor： 유현승 ,  홍국선 ,  김환 ,  이동호 ,  이춘기 ,  장봉순 ,  김득중 ,  서준혁 ,  이재협 ,  박기수

IPC: A61L27/10

CPC classification number: C03C4/0007 ,  A61L27/10 ,  A61L27/58 ,  C03C3/064 ,  C03C3/112 ,  C03C4/0014 ,  C03C8/22 ,  C03C10/00 ,  C03C11/00 ,  C03C12/00

Abstract: PURPOSE: A bioabsorbable type bioactive glass-ceramic and a preparation method thereof are provided to control the biodegradable speed according to the formulation ratio of glass-ceramics while maintaining the bioactivity. CONSTITUTION: The bioabsorbable type bioactive glass-ceramic comprises 41.4 to 45.75 wt.% of CaO, 35.0 to 47.62 wt.% of SiO2, 1.62 to 14.58 wt.% of P2O5, 0.5 to 14.58 wt.% of B2O3, 0.46 to 4.14 wt.% of MgO, and 0.05 to 0.45 wt.% of CaF2. The bioabsorbable type bioactive glass-ceramic is composed of the first glass and the second glass in a weight ratio of 90:10 to 10:90. The first glass comprises 41.03 to 45.86 wt.% of CaO, 43.97 to 49.14 wt.% of SiO2, and 5 to 15 wt.% of B2O3. The second glass comprises 44.7 wt.% of CaO, 44.7 wt.% of MgO, 34.0 wt.% of SiO2, 16.2 wt.% of P2O5, and 0.5 wt.% of CaF2.

Abstract translation: 目的：提供生物可吸收型生物活性玻璃陶瓷及其制备方法，以在保持生物活性的同时，根据玻璃陶瓷配方比例控制生物降解速度。 构成：生物可吸收型生物活性玻璃 - 陶瓷包含41.4〜45.75重量％的CaO，35.0〜47.62重量％的SiO 2，1.62〜14.58重量％的P 2 O 5，0.5〜14.58重量％的B 2 O 3，0.46〜4.14重量％ 的MgO，0.05〜0.45重量％的CaF 2。 生物可吸收型生物活性玻璃陶瓷由第一玻璃和第二玻璃组成，重量比为90:10至10:90。 第一玻璃包含CaO的41.03〜45.86重量％，SiO 2为43.97〜49.14重量％，B 2 O 3为5〜15重量％。 第二种玻璃包括44.7wt％的CaO，44.7wt％的MgO，34.0wt。％的SiO 2，16.2wt。％的P 2 O 5和0.5wt％的CaF 2。

公开(公告)号：KR1020040011885A

公开(公告)日：2004-02-11

申请号：KR1020020045175

申请日：2002-07-31

Applicant: 재단법인서울대학교산학협력재단

Inventor： 유현승 ,  홍국선 ,  이춘기 ,  이동호 ,  이재협 ,  장봉순 ,  김수진 ,  정성수

IPC: A61L27/10

Abstract: PURPOSE: Provided are a bio-active ceramics and a metallic implant used in surgical and dental applications coated with the ceramics in order to increase bio-affinity to a subject having the implant. CONSTITUTION: The bio-active ceramics comprises 40-49 wt.% of CaO, 40-49 wt.% of silica(SiO2) and 2-20 wt.% of B2O3. The process for producing the metallic implant comprises steps of preparing the bio-active ceramic by fusing raw material consisting of CaO, SiO2, B2O3 and quenching the fused material; grinding the frozen material into powders having less than 10 micrometer size; preparing slurry by adding aqueous or organic solvents and a binder; applying the slurry to a metallic implant by means of brush; and sintering the coated implant at 700-950 deg.C.

Abstract translation: 目的：提供一种生物活性陶瓷和用于外科和牙科应用的金属植入物，其涂覆有陶瓷，以增加对具有植入物的受试者的生物亲和力。 构成：生物活性陶瓷包含40-49重量％的CaO，40-49重量％的二氧化硅（SiO 2）和2-20重量％的B 2 O 3。 制造金属植入体的方法包括以下步骤：通过熔融由CaO，SiO 2，B 2 O 3组成的原料和淬火熔融材料来制备生物活性陶瓷; 将冷冻材料研磨成具有小于10微米尺寸的粉末; 通过加入水或有机溶剂和粘合剂制备浆料; 通过刷子将浆料施加到金属植入物; 并在700-950℃烧结涂覆的植入物。