公开(公告)号：KR100460685B1

公开(公告)日：2004-12-09

申请号：KR1020020019520

申请日：2002-04-10

Applicant: 재단법인서울대학교산학협력재단

Inventor： 유현승 ,  홍국선 ,  이춘기 ,  이동호 ,  이상림 ,  장봉순 ,  김수진 ,  임창균

IPC: A61L27/12

CPC classification number: A61L27/12 ,  A61F2/4644 ,  A61F2002/2835 ,  A61F2310/00293 ,  A61L27/56 ,  A61L2430/02

Abstract: A bone graft substitute using magnesium substituted calcium phosphate compounds and a method of manufacturing the same is provided in which the bone graft substitute is used for recovering bones damaged due to a bone fracture. The method of manufacturing a bone graft substitute includes the steps of mixing powdered calcium pyrophosphate and a magnesium included compound to thereby obtain a composition, pressure-forming the compositions to obtain a plastic body; and sintering the plastic body.

Abstract translation: 提供了使用镁取代磷酸钙化合物的骨移植替代物及其制造方法，其中骨移植替代物用于恢复由于骨折而损坏的骨。 制造骨移植替代品的方法包括以下步骤：将粉状焦磷酸钙和含镁化合物混合，从而获得组合物，将组合物加压成形以获得塑性体; 并烧结塑料体。

公开(公告)号：KR1020030080736A

公开(公告)日：2003-10-17

申请号：KR1020020019520

申请日：2002-04-10

Applicant: 재단법인서울대학교산학협력재단

Inventor： 유현승 ,  홍국선 ,  이춘기 ,  이동호 ,  이상림 ,  장봉순 ,  김수진 ,  임창균

IPC: A61L27/12

CPC classification number: A61L27/12 ,  A61F2/4644 ,  A61F2002/2835 ,  A61F2310/00293 ,  A61L27/56 ,  A61L2430/02

Abstract: PURPOSE: An artificial bone filler using calcium phosphate based compounds and a preparation method are provided to have not only the high bone fusion rate and tensile strength, but also the relatively high bio-absorbency. CONSTITUTION: The artificial bone filler is prepared by: formulating at least one selected from the group consisting of magnesium oxide(MgO), calcium pyrophosphate substituted by Mg(Ca2-XMgXP2O7), magnesium pyrophosphate(Mg2P2O7) and calcium magnesium pyrophosphate(CaMg2P2O7), and calcium pyrophosphate powders selected from the group consisting of calcium pyrophosphate(Ca2P2O7) or not more than 10 wt.% of tricalcium phosphate(Ca3(PO4)2); press-forming the compounds to a porous body; and sintering it at the temperature of 1000 to 1200 deg.C.

Abstract translation: 目的：提供一种使用磷酸钙基化合物的人造骨填料和制备方法，不仅具有高骨融合率和拉伸强度，而且具有较高的生物吸收性。 构成：通过以下方法制备人造骨填料：配制选自由Mg（Ca2-XMgXP2O7），焦磷酸镁（Mg2P2O7）和焦磷酸钙镁（CaMg2P2O7）取代的氧化镁（MgO），焦磷酸钙的至少一种， 和选自焦磷酸钙（Ca2P2O7）或不超过10重量％的磷酸三钙（Ca 3（PO 4）2））的焦磷酸钙粉末; 将化合物压制成多孔体; 并在1000〜1200℃的温度下烧结。