Abstract:
본 발명은 미세 캡슐 조성물에 관한 것으로서 보다 구체적으로는 퍼플루오데칼린 교질 입자를 함유하는 췌도 이식용 알긴산 미세 캡슐 조성물 및 이의 제조 방법 등에 관한 것이다. 본 발명에 따르면, 알긴산 캡슐을 칼슘이 아닌 바륨만을 이용함으로써, 추가적인 코팅 공정 없이도 강도가 강하게 할 수 있다. 또한, 플루오닉 F68만을 이용하여 퍼플루오데칼린을 교질 입자화하여 미세 캡슐 내에 삽입함으로써, 알긴산 미세 캡슐 내에 퍼플루오데칼린이 균일하게 많은 양이 존재할 수 있도록 한다. 즉, 본 발명에 따르며, 제조 공정이 간소화되고, 항원성 물질을 최소화함으로써, 췌도의 생존율이 더 높아지도록 하며, 제조 비용이 절감될 수 있다. 따라서, 본 발명에 따른 미세 캡슐화된 췌도는 수혜자당 2인의 공여자가 필요한 현 췌도 이식 환경에서 공여자의 선택의 폭을 넓히는 동시에, 초기 저산소에 의한 췌도의 손상을 억제하여 인슐린 의존성 당뇨병 치료에 기여할 것으로 기대된다.
Abstract:
The present invention relates to a composition for cleaning an eyeball, containing mineral water as an active ingredient, and more particularly, to a composition for cleaning an eyeball and to a composition for preventing or treating eyeball damages, wherein the composition comprises, as mineral components, 200 to 230 mg/L of potassium, 7000 to 9500 mg/L of sodium, 1400 to 1700 mg/L of calcium, 900 to 1100 mg/L of magnesium, 3 to 9 mg/L of zinc, 25 to 35 mg/L of strontium, 200 to 500 μg/L of selenium, 65 to 75 μg/L of vanadium, 0.5 to 1.5 μg/L of germanium, 10 to 40 μg/L of manganese, 1 to 3 μg/L of cobalt, 600 to 950 μg/L of titanium, 3 to 9 μg/L of copper, 0.02 to 0.09 mg/L of lithium, 16000 to 19500 mg/L of chloride ion, 1.5 to 3.0 mg/L of fluoride ion, 40 to 56 mg/L of bromide ion, 3000 to 4500 mg/L of sulfate ion, 0.8 to 1.2 mg/L of boron and 0.5 to 15 mg/L of silicon dioxide. The mineral water, which is the active ingredient of the composition for cleaning an eyeball and the composition for preventing or treating eyeball damages according to the present invention, has effects in inhibiting toxicity with respect to corneal epithelia cells and reducing thickness changes of a cornea, as well as excellent effects in reducing the number of macrophages invaded in the inside of the cornea, and thereby, being able to be widely used in manufacturing mineral water, a treating agent and functional health food for cleaning for an eyeball capable of relieving, preventing and treating cornea damage symptoms. [Reference numerals] (AA) Mineral water 10%;(BB) Mineral water 20%
Abstract:
PURPOSE: A composition for preventing and treating fatty liver disease is provided to be used for the prevention or treatment of the fatty liver disease since mineral water in the composition has activities to decrease the content of ALP, AST, reducing cholesterol, TG, ALB, T bilirubin, glucose, and ALP. CONSTITUTION: A composition for preventing and treating fatty liver disease contains marine mineral water collected from 1100 m spot from the ground at the hot spring area of marine terrace located in 92-1, Keumjin 3-ri, Okgye-myeon, Kangnung city, Kangwon-do, Korea. The mineral water contains 200-230 mg/L of potassium, 7000-9500 mg/L of sodium, 1400-1700 mg/L of calcium, 900-1100 mg/L of magnesium, 3-9 mg/L of zinc, 25-35 mg/L of strontium, 200-500 ug/L of selenium, 65-75 ug/L of vanadium, 0.5-1.5 ug/L of germanium, 10-40 ug/L of manganese, 1-3 ug/L of cobalt, 600-950 ug/L of titanium, 3-9 ug/L of copper, 0.02-0.09 mg/L of lithium, 16000-19500 mg/L of chlorine ion, 1.5-3.0 mg/L of fluorine, 40-56 mg/L of bromide ion, 3000-4500 mg/L of sulfate ion, 0.8-1.2 mg/L of boron, and 0.5-15 mg/L of silicon dioxide as mineral ingredients.
Abstract:
PURPOSE: An alginic acid microcapsule composition is provided to simplify capsule production process and to minimize damage to islet. CONSTITUTION: An alginic acid microcapsule composition contains perfluorodecalin, pluronic F68, alginic acid, and barium. Alginic acid forms a semi-permeable capsule by crosslinking using the barium. The perfluorodecalin is formed in colloid in the semi-permeable capsule by pluronic F68. The perfluorodecalin and pluronic F68 are mixed in a ratio of 3:7-7:3.
Abstract:
사용자가 자가측정을 통하여 측정한 혈당값을 이용하여 당화혈색소 수치를 추정하여 이를 제공하는 시스템 및 방법이 제공된다. 본 발명은 사용자가 입력한 자가측정 혈당값을 저장하고, 저장된 혈당값 자료를 이용하여 1개월 후의 사용자의 당화혈색소 수치의 예측치를 추정하고, 이를 사용자에게 제공함으로써, 병원을 방문하여 별도의 검사를 받지 않고도 1개월 후의 당화혈색소 수치를 미리 예측할 수 있도록 한다. 당화혈색소, 혈당, 자가측정, 예측, 회귀분석, 추정
Abstract:
PURPOSE: An internet-based management system for health check-up data and an automatic classification of metabolic diseases are provided to offer the interpretation of the result of medical examination to the target person to help understanding. CONSTITUTION: A system receives the health medical examination data and interview data of health medical examination objects. The system automatically classifies the different conditions according to the state of objects. The system systematically manages the states of objects. The system offers the health medical examination interview sheet by matching the past medication examination data with the current medical examination data. The health medical examination interview sheet includes not only the result value but also the interpretation and description about the result.
Abstract:
본 발명은 miR-374를 유효성분으로 포함하는 조성물을 이용하여 당뇨병을 예방, 개선 또는 치료하는 기술에 관한 것으로서, 더욱 구체적으로는 PGC-1α(Peroxysome proliferative activated receptor-γ co-activator-1α)의 발현을 감소시킴으로써 인슐린 발현 및 분비를 조절하는 miR-374의 활용에 관한 것이다. 본 발명에 따른 miR-374를 세포 내 과발현시키면 간과 췌장에서 인슐린 분비 및 세포 내 인슐린 함량이 증가되는 효과가 있으므로, 효과적으로 당뇨를 예방, 개선 및 치료함으로써 삶의 질을 증진시킬 수 있는 장점이 있다.