Abstract:
PURPOSE: A novel Enterococcus faecalis K-60(KFCC11460P) is provided to maintain glucose homeostasis and to treat diabetes. CONSTITUTION: A novel Enterococcus faecalis K-60 strain(KFCC 11460P) is used for fermenting ginseng. A method for preparing the ginseng fermentation extract comprises: a step of fermenting ginseng with Enterococcus faecalis K-60 strain to obtain a fermentation; and a step of extracting the fermentation with a solvent and filtering. A pharmaceutical composition for maintaining or improving glucose homeostasis contains the ginseng fermentation extract. A health food for maintaining or improving glucose homeostasis contains ginseng fermentation extract.
Abstract:
PURPOSE: An extract for improving glucose homeostasis, which is produced by fermenting ginseng with lactobacillus is provided to maintain or improve glucose homeostasis and to be effectively used in treating diabetes. CONSTITUTION: A method for manufacturing a ginseng fermentation extract for improving glucose homeostasis comprises: a step of suspending ginseng powder in purified water; a step of fermenting the suspended liquid of ginseng powder with lactobacillus; a step of extracting the fermentation and filtering; and a step of decompressing the filtered liquid. Lactobacillus is bifidobacterium longum KFRI 00977. The extraction solvent is ethanol or butanol. The white, red, and sun ginseng extract is isolated by extracting with ethanol or butanol at 60°C-80°C for two to four hours. A ginseng fermentation extract for improving glucose homeostasis contains 3.0-6.0% of Rh1, 0.2-0.8% of comp. K, and 0-1.0% of Rh2 ginsenoid.
Abstract:
본 발명은 갈근 또는 갈화 추출물의 유산균 발효물을 유효성분으로 함유하는 비만 또는 고지혈증의 예방 또는 치료용 조성물에 관한 것으로서, 보다 상세하게는 갈근 또는 갈화에 물을 가한 후 열수추출하고 상기 수추출물에 유산균을 접종하여 발효시킴으로써 제조되는 갈근 또는 갈화 수추출물의 유산균 발효물을 유효성분으로 함유하는 비만 또는 고지혈증의 예방 또는 치료용 약학적 조성물 및 건강식품에 관한 것이다. 갈근 또는 갈화 추출물의 발효물은 갈근 또는 갈화 추출물만으로는 얻을 수 없는 뛰어난 비만 및 고지혈증 개선효과를 보이며, 알콜, 특히 독성이 있는 메탄올과 같은 유기용매를 사용하지 않아 인체에 적용시키기 위한 고도의 정제과정이 필요하지 않으므로, 비만 및 고지혈증의 예방 또는 치료에 유용하게 사용될 수 있다. 갈근, 갈화, 추출물, 발효물, 비만, 고지혈증
Abstract:
A fermented product of a water extract of Puerariae Radix or Puerariae Flos is provided to have better obesity or hyperlipidemia prophylactic or therapeutic effect than that of an extract of Puerariae Radix or Puerariae Flos and do not require a step for removing a toxic organic solvent such as methanol, thereby being usefully used for preventing or treating obesity and hyperlipidemia. The pharmaceutical composition for preventing and treating obesity or hyperlipidemia comprises a fermented product of a water extract of Puerariae Radix or Puerariae Flos which is prepared by hot-water extracting Puerariae Radix or Puerariae Flos and then inoculating 1-5 wt.% of lactic acid bacteria such as Bifidobacterium, Lactobacillus, Streptococcus, Leuconostoc, Pediococcus and Lactococcus into the extract to ferment it at a temperature of 30-40 deg.C for 24-52 hours.
Abstract:
A fermented product of a water extract of Puerariae Radix is provided to show more excellent osteoporosis prophylactic or therapeutic effect than that of an extract of Puerariae Radix and be extracted with water rather than an alcohol, specifically a toxic aqueous solution of methanol, thereby not requiring a further purification step. The fermented product of a water extract of Puerariae Radix is prepared by hot-water extracting Puerariae Radix and then inoculating lactic acid bacteria such as Bifidobacterium, Lactobacillus, Streptococcus, Leuconostoc, Pediococcus and Lactococcus into the extract to ferment it. The pharmaceutical composition for preventing or treating osteoporosis comprises the fermented product of the water extract of Puerariae Radix as an effective ingredient.
Abstract:
본 발명은 신규한 페디오코커스 펜토사시우스 케이-61 균주(Pediococcus pentosaceus K-61)(KFCC11461P)(이하 K-61로 약칭함) 및 상기 균주를 이용한 인삼 발효물의 제조방법에 관한 것으로서 보다 상세하게는 인삼을 발효시킬 수 있는 신규한 K-61 및 상기 균주로 인삼을 발효시켜 포도당 항상성 개선에 적용할 수 있는 인삼 발효 추출물 및 이의 제조방법에 관한 것이다. 본 발명의 인삼을 K-61로 발효시켜 얻은 인삼 발효 추출물은 포도당 항상성 유지 혹은 개선 효과가 우수하여 공복혈당장애자, 내당능장애자, 당뇨병 전단계로 진단받은 자 및 당뇨병 환자의 치료 및/또는 예방에 효과가 있다. 페디오코커스 펜토사시우스 케이-61 균주, 인삼 발효, 포도당 항상성, 당뇨병, 혈당강하
Abstract:
PURPOSE: A ginseng fermentation extract using a novel Pediococcus pentosaceus K-51 is provided to enhance insulin secretion and to treat diabetes. CONSTITUTION: A novel Pediococcus pentosaceus K-51(KFCC11465P) is able to ferment ginseng. A method for preparing a ginseng fermentation extract comprises: a step of fermenting ginseng powder with Pediococcus pentosaceus K-51(KFCC11465P) at 35-37 degrees Celsius for 3-10 days to obtain fermentation; and a step of filtering the fermentation using ethanol, spirit, or butanol at 60-80 degrees Celsius for 2-4 hours. A pharmaceutical formulation for enhancing insulin secretion contains the ginseng fermentation extract.
Abstract:
PURPOSE: A novel Pediococcus pentosaceus K-61 strain and a method for preparing a ginseng fermentation using the same are provided to maintain and improve glucose homeostasis. CONSTITUTION: A novel Pediococcus pentosaceus K-61(KFCC11461P) strain is isolated from human feces and has ginseng fermenting ability. A method for preparing a ginseng fermentation extract comprises: a step of fermenting ginseng powder suspension with Pediococcus pentosaceus K-61(KFCC11461P) at 35-37°C for 3-10 days to obtain fermentation; and a step of extracting the fermentation using ethanol, spirit, or butanol at 60°C-80°C for 2-4 hours.
Abstract:
PURPOSE: A Pediococcus pentosaceus K-641(KFCC11463P) is provided to convert ginsenoside of low bioavailability to ginsenoside of high bioavailability and to improve glucose homeostasis. CONSTITUTION: A novel Pediococcus pentosaceus K-641(KFCC11463P) is used for fermenting ginseng. A method for preparing ginseng fermentation extract comprises: a step of fermenting a suspension of ginseng power with Pediococcus pentosaceus K-641(KFCC11463P) at 35-37 degrees Celsius for 3-10 days to obtain a fermentation; a step of extracting the fermentation with a solvent of ethanol, spirit, or butanol; and a step of filtering the extract.
Abstract:
PURPOSE: A novel Pediococcus pentosaceus K-643(KFCC11464P) is provided to improve glucose homeostasis. CONSTITUTION: A novel Pediococcus pentosaceus K-643(KFCC11464P) is used in fermenting ginseng. A method for preparing the ginseng fermentation extract comprises: a step of fermenting ginseng with Pediococcus pentosaceus K-643(KFCC11464P) to obtain a fermentation; and a step of extracting the fermentation with a solvent and filtering. A pharmaceutical formulation and health food for maintaining or improving glucose homeostasis contains ginseng fermentation extract.