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    Locking rack and disposable sample cartridge
    11.
    发明公开
    Locking rack and disposable sample cartridge 失效
    Verschliess-EinschubbehälterundzugehörigerWegwerf-Probenträger。

    公开(公告)号：EP0287900A2

    公开(公告)日：1988-10-26

    申请号：EP88105532.1

    申请日：1988-04-07

    Applicant: ABBOTT LABORATORIES

    Inventor： Grandone, Cass J.

    IPC: G01N35/04 ,  B01L3/00

    CPC classification number: B01L3/5025

    Abstract: A plurality of disposable cartridges (20), each having a plurality of wells including at least one assay reaction well, are loaded in a plurality of open­ings arranged radially around a rack (30) of a carousel (10). Securing of the cartridges in a predetermined orienta­tion and position in said openings is ensured by means of alignment and securing means on the cartridges and corresponding means on the rack. A locking hub (40) with tangs is mounted on the rack and is rotated to cause the tangs to contact locator tabs on each cartridge to force locator nubs on each of the cartridges radially into corresponding notches on the rack, and to accura­tely wedge the cartridges against the outer periphery of the rack. The carousel indexes for positioning the cartridges under a variety of stations, one of which generally contains an optical reader such as a fluoro­meter.

    Abstract translation: 多个具有包括至少一个测定反应井的多个孔的一次性盒（20）被装载在放置在圆盘传送带（10）的齿条（30）周围的多个开口中。 通过在盒上的对准和固定装置以及机架上的对应装置来确保盒子在所述开口中的预定取向和位置的固定。 具有柄脚的锁定毂（40）安装在齿条上并被旋转以使脚部接触每个卡盘上的定位器突出部，以将每个卡盘上的定位器卡扣径向地插入到齿条上相应的凹口中，并准确地楔住墨盒 抵靠机架的外周。 用于将盒定位在各种站下的转盘索引，其中一个通常包含诸如荧光计的光学读取器。

    Automatic analyser
    18.
    发明公开
    Automatic analyser 失效
    自动分析仪

    公开(公告)号：EP0831329A3

    公开(公告)日：1998-08-12

    申请号：EP97114411.8

    申请日：1997-08-20

    Applicant: Abbott Laboratories

    Inventor： Arnquist, David C. ,  Barnes, Grady, III ,  Button, Richard D. ,  Dunn, Chadwick M. ,  East, Richard C., Jr. ,  Fritchie, Patrick P. ,  Galitz, Charles M. ,  Grandone, Cass J. ,  Gardner, Gregory E. ,  Gray, Robert C. ,  Holen, James T. ,  Luoma, Robert P., II ,  McCory, Jimmy D. ,  Mitchell, James E. ,  Murray, Adrian John ,  Murray, David W. ,  Ramsey, Jack F. ,  Sleszynski, Neal T. ,  Toth, Julius J.

    IPC: G01N35/04

    CPC classification number: B01L3/508 ,  B01L2300/0851 ,  G01N21/76 ,  G01N35/0092 ,  G01N35/025 ,  G01N35/04 ,  G01N2035/00534 ,  G01N2035/00752 ,  G01N2035/0465 ,  G01N2035/0467

    Abstract: The structure embodiments disclosed relate to determination of an item of interest in a sample. One embodiment relates to a structure which comprises a process path (10). The process path (10) comprises a process lane (28) including a process step performance lane (62) where a process step is performed, and a process step avoidance lane (64) where the process step is avoided. A first prime mover (24) is operatively connected with the process path (10) for moving a container (15) holding the sample along the process path (10). A first pipetting system (198) is operatively associated with the process path (10) for introducing the sample to the container (15). A second pipetting system (132, 134) is operatively associated with the process path (10) for introducing a reagent to the container (15). A device (86) is operatively connected with the process path (10) and is selectively engagable with the container (15) for mixing the sample and the reagent in the container (15). A second prime mover (44) is operatively connected with the process path (10) for selectively positioning the container (15) in a selected one of the process step performance lane (62) and the process step avoidance lane (64). A reader (138) is operatively connected with the process path (10) for determining the item of interest in the sample based upon a reaction between the sample and the reagent. The method embodiments disclosed relate to determination of an item of interest in a sample. In one method, a process path (10) comprising a process lane (28) including a process step performance lane (62) where a process step is performed, and a process step avoidance lane (64) where the process step is avoided is provided. A container (15) holding the sample is moved along the process path (10). The sample is introduced to the container (15). A reagent is introduced to the container (15). The sample and the reagent are mixed in the container (15). The container (15) is selectively positioned in a selected one of the process step performance lane (62) and the process step avoidance lane (64). The item of interest in the sample is determined based upon a reaction between the sample and the reagent.

    Abstract translation: 所公开的结构实施例涉及确定样本中的感兴趣项目。 一个实施例涉及一种包括处理路径（10）的结构。 处理路径（10）包括处理通道（28），处理通道（28）包括执行处理步骤的处理步骤执行通道（62）和避免处理步骤的处理步骤避免通道（64）。 第一原动机（24）与处理路径（10）可操作地连接，用于沿着处理路径（10）移动容纳样品的容器（15）。 第一移液系统（198）可操作地与处理路径（10）相关联以将样品引入容器（15）。 第二移液系统（132,134）与处理路径（10）可操作地相关联以将试剂引入容器（15）。 装置（86）与处理路径（10）可操作地连接，并可选择性地与容器（15）接合，以将样品和试剂混合在容器（15）中。 第二原动机（44）与处理路径（10）可操作地连接，用于将容器（15）选择性地定位在处理步骤性能通道（62）和处理步骤避免通道（64）中的选定的一个中。 读取器（138）与处理路径（10）可操作地连接，用于基于样本与试剂之间的反应来确定样本中的感兴趣项目。 所公开的方法实施例涉及确定样本中的感兴趣项目。 在一种方法中，提供包括处理通道（28）的处理路径（10），该处理通道包括执行处理步骤的处理步骤执行通道（62）和避免处理步骤的处理步骤避免通道（64） 。 保持样品的容器（15）沿着处理路径（10）移动。 样品被引入容器（15）。 试剂被引入容器（15）。 样品和试剂在容器（15）中混合。 容器（15）选择性地定位在处理步骤执行通道（62）和处理步骤回避通道（64）中选定的一个中。 样品中感兴趣的项目是基于样品和试剂之间的反应来确定的。

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