公开(公告)号：EP1079870B1

公开(公告)日：2001-11-14

申请号：EP99916347.0

申请日：1999-04-01

Applicant: Alcon Laboratories, Inc.

Inventor： SHEETS, John, W., Jr. ,  LEBOEUF, Albert, R. ,  PATEL, Anilbhai, S. ,  KARAKELLE, Mutlu ,  VAN NOY, Stephen, J.

IPC: A61L27/00 ,  G02B1/04

CPC classification number: A61L27/16 ,  A61L2430/16 ,  C08L33/00

Abstract: Bicomposite intraocular lenses having an anterior surface material different from a posterior surface material are disclosed. The posterior surface material reduces the risk of posterior capsule opacification.

Abstract translation: 公开了具有不同于后表面材料的前表面材料的双复合人工晶状体。 后表面材料降低了后囊混浊的风险。

公开(公告)号：EP0739218A1

公开(公告)日：1996-10-30

申请号：EP95939997.0

申请日：1995-11-16

Applicant: ALCON LABORATORIES, INC.

Inventor： Llanos, Gerard ,  KARAKELLE, Mutlu ,  HARRIS, Joe, Milton

IPC: A61L27 ,  A61L2 ,  A61L29 ,  A61L33

CPC classification number: A61F2/16 ,  A61L2/206 ,  A61L27/34 ,  A61L29/085 ,  A61L33/068 ,  C08L71/02

Abstract: Polyethylene oxide (PEO) coatings providing improved biocompatibility for implantable medical devices are disclosed. The PEO coatings comprise functionalized, end-capped PEO which is attached at one end to the medical device. The PEO compounds are then cross-linked by 1) exposure to a high energy source for a time sufficient to cause the PEO compounds to form a cross-linked, insoluble network or 2) by reacting the free functionalized ends of a sufficient number of bound PEO compounds with a crosslinking agent whose functional groups are reactive toward the bound PEO chain's functionalized ends. These PEO coatings are able to survive ethylene oxide sterilization procedures with minimal loss of protein or cell repulsion ability.

公开(公告)号：EP0914169B1

公开(公告)日：2003-07-30

申请号：EP98925025.3

申请日：1998-05-29

Applicant: ALCON LABORATORIES, INC.

Inventor： GRAFF, Gustav ,  KARAKELLE, Mutlu ,  SHEETS, John, W., Jr. ,  YANNI, John, M.

IPC: A61L31/04

CPC classification number: A61L31/048 ,  Y10S623/901 ,  C08L33/04

Abstract: Improved glaucoma filtration device materials comprise at least one monomer having formula (I) wherein X is H or CH3; m is 0-10; Y is nothing, O, or S; R is nothing, H, or an aliphatic, aromatic or aliphatic/aromatic combination of up to twelve carbon atoms, which can be unsubstituted or substituted with Cl, F, Br, or an alkoxy of up to four carbon atoms; and a cross-linking monomer having two or more ethylenically unsaturated groups.

公开(公告)号：EP0914169A3

公开(公告)日：2002-08-28

申请号：EP98925025.3

申请日：1998-05-29

Applicant: ALCON LABORATORIES, INC.

Inventor： GRAFF, Gustav ,  KARAKELLE, Mutlu ,  SHEETS, John, W., Jr. ,  YANNI, John, M.

IPC: A61L31/00

CPC classification number: A61L31/048 ,  Y10S623/901 ,  C08L33/04

公开(公告)号：EP1002243B1

公开(公告)日：2001-11-14

申请号：EP98934448.6

申请日：1998-07-14

Applicant: ALCON LABORATORIES, INC.

Inventor： LEBOEUF, Albert, R. ,  KARAKELLE, Mutlu

IPC: G02B1/04 ,  A61L27/00 ,  C08F2/50

CPC classification number: G02B1/043 ,  A61L27/16 ,  A61L2430/16 ,  C08L33/06

Abstract: Foldable, hydrophilic, ophthalmic device materials are cured by exposure to blue light using a benzoylphosphine oxide photoinitiator.

公开(公告)号：EP1002244A1

公开(公告)日：2000-05-24

申请号：EP98934449.4

申请日：1998-07-14

Applicant: ALCON LABORATORIES, INC.

Inventor： LEBOEUF, Albert, R. ,  KARAKELLE, Mutlu

IPC: G02B1/04 ,  A61L27/00 ,  C08F2/50 ,  C08F20/18

CPC classification number: G02B1/043 ,  A61L27/16 ,  A61L27/50 ,  A61L2430/16 ,  C08L33/04

Abstract: Foldable, acrylic, high refractive index ophthalmic device materials containing a UV absorbing chromophore are cured by exposure to blue light using a benzoylphosphine oxide photoinitiator.

公开(公告)号：EP1002243A1

公开(公告)日：2000-05-24

申请号：EP98934448.6

申请日：1998-07-14

Applicant: ALCON LABORATORIES, INC.

Inventor： LEBOEUF, Albert, R. ,  KARAKELLE, Mutlu

IPC: G02B1/04 ,  A61L27/00 ,  C08F2/50

CPC classification number: G02B1/043 ,  A61L27/16 ,  A61L2430/16 ,  C08L33/06

Abstract: Foldable, hydrophilic, ophthalmic device materials are cured by exposure to blue light using a benzoylphosphine oxide photoinitiator.