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公开(公告)号:NO932860A
公开(公告)日:1994-02-14
申请号:NO932860
申请日:1993-08-11
Applicant: BASF AG
Inventor: KAISER KLAUS , BALKENHOHL FRIEDHELM , PAUST JOACHIM
CPC classification number: C07F9/65515
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公开(公告)号:DK0801683T3
公开(公告)日:2002-06-17
申请号:DK96900601
申请日:1996-01-20
Applicant: BASF AG
Inventor: BALKENHOHL FRIEDHELM , DITRICH KLAUS , NUEBLING CHRISTOPH
Abstract: A process for preparing optically active primary and secondary heteroatom-substituted amines from the corresponding racemates, which comprisesa) enantioselective acylation of a racemic heteroatom-substituted amine with an ester whose acid component carries a fluorine, nitrogen, phosphorus, oxygen or sulfur atom in the vicinity of the carbonyl carbon, in the presence of a hydrolase,b) separation of the mixture of optically active heteroatom-substituted amine and optically active acylated heteroatom-substituted amine to obtain one enantiomer of the heteroatom-substituted amine,c) if required isolation of the other enantiomer of the heteroatom-substituted amine from the acylated heteroatom-substituted amine by amide cleavage.
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公开(公告)号:DE59604905D1
公开(公告)日:2000-05-11
申请号:DE59604905
申请日:1996-09-09
Applicant: BASF AG
Inventor: DITRICH KLAUS , BALKENHOHL FRIEDHELM , LADNER WOLFGANG
IPC: C12M1/40 , B01J23/04 , C07B53/00 , C07B61/00 , C07C69/708 , C07C209/62 , C07C211/27
Abstract: PCT No. PCT/EP96/03948 Sec. 371 Date Jan. 27, 1998 Sec. 102(e) Date Jan. 27, 1998 PCT Filed Sep. 9, 1996 PCT Pub. No. WO97/10201 PCT Pub. Date Mar. 20, 1997The present invention relates to a process for cleaving optically active amides to carboxylic acids and optically active amines with retention of the center of chirality, wherein the amides are hydrolyzed in the presence of a polyol or of an amino alcohol and of an alkali metal or alkaline earth metal hydroxide.
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公开(公告)号:DK0720655T3
公开(公告)日:2000-04-10
申请号:DK94928365
申请日:1994-09-16
Applicant: BASF AG
Inventor: BALKENHOHL FRIEDHELM , HAUER BERNHARD , LADNER WOLFGANG , PRESSLER UWE , N BLING CHRISTOPH
Abstract: PCT No. PCT/EP94/03102 Sec. 371 Date Mar. 11, 1996 Sec. 102(e) Date Mar. 11, 1996 PCT Filed Sep. 16, 1994 PCT Pub. No. WO95/08636 PCT Pub. Date Mar. 30, 1995A process for producing optically active primary and secondary amines from the corresponding racemates is characterised in that (a) a racemic amine is enantioselectively acylated in the presence of a hydrolase with an ester whose acid component bears a fluorine, nitrogen, oxygen or sulphur atom at the proximity of the carbonyl carbon atom; (b) the mixture of optically active amine and optically active acylated amine is separated so that an enantiomer of amine is produced; (c) if desired the other enantiomer of the amine is extracted from the acylated amine by amide cleavage.
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公开(公告)号:DE59409010D1
公开(公告)日:2000-01-20
申请号:DE59409010
申请日:1994-09-16
Applicant: BASF AG
Inventor: BALKENHOHL FRIEDHELM , HAUER BERNHARD , LADNER WOLFGANG , PRESSLER UWE , NUEBLING CHRISTOPH
Abstract: PCT No. PCT/EP94/03102 Sec. 371 Date Mar. 11, 1996 Sec. 102(e) Date Mar. 11, 1996 PCT Filed Sep. 16, 1994 PCT Pub. No. WO95/08636 PCT Pub. Date Mar. 30, 1995A process for producing optically active primary and secondary amines from the corresponding racemates is characterised in that (a) a racemic amine is enantioselectively acylated in the presence of a hydrolase with an ester whose acid component bears a fluorine, nitrogen, oxygen or sulphur atom at the proximity of the carbonyl carbon atom; (b) the mixture of optically active amine and optically active acylated amine is separated so that an enantiomer of amine is produced; (c) if desired the other enantiomer of the amine is extracted from the acylated amine by amide cleavage.
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公开(公告)号:AT187774T
公开(公告)日:2000-01-15
申请号:AT94928365
申请日:1994-09-16
Applicant: BASF AG
Inventor: BALKENHOHL FRIEDHELM , HAUER BERNHARD , LADNER WOLFGANG , PRESSLER UWE , NUEBLING CHRISTOPH
Abstract: PCT No. PCT/EP94/03102 Sec. 371 Date Mar. 11, 1996 Sec. 102(e) Date Mar. 11, 1996 PCT Filed Sep. 16, 1994 PCT Pub. No. WO95/08636 PCT Pub. Date Mar. 30, 1995A process for producing optically active primary and secondary amines from the corresponding racemates is characterised in that (a) a racemic amine is enantioselectively acylated in the presence of a hydrolase with an ester whose acid component bears a fluorine, nitrogen, oxygen or sulphur atom at the proximity of the carbonyl carbon atom; (b) the mixture of optically active amine and optically active acylated amine is separated so that an enantiomer of amine is produced; (c) if desired the other enantiomer of the amine is extracted from the acylated amine by amide cleavage.
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公开(公告)号:ZA976637B
公开(公告)日:1999-01-25
申请号:ZA976637
申请日:1997-07-25
Applicant: BASF AG
Inventor: MACK HELMUT , PFEIFFER THOMAS , SEITZ WERNER , ZIERKE THOMAS , BALKENHOHL FRIEDHELM , LANGE UDO
IPC: C12P17/04 , C07D207/22 , C07D401/12 , C07D , C07B
Abstract: PCT No. PCT/EP97/03752 Sec. 371 Date Jan. 22, 1999 Sec. 102(e) Date Jan. 22, 1999 PCT Filed Jul. 14, 1997 PCT Pub. No. WO98/04523 PCT Pub. Date Feb. 5, 19983-Pyrroline-2-carboxylic acid derivatives of the formula I are prepared by eliminating the sulfonic acid residue, with the aid of a base, from a compound of the formula II
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公开(公告)号:ES2120055T3
公开(公告)日:1998-10-16
申请号:ES94919662
申请日:1994-06-24
Applicant: BASF AG
Inventor: PRESSLER UWE , BALKENHOHL FRIEDHELM , HAUER BERNHARD , LADNER WOLFGANG , SCHNELL URSULA , STAUDENMAIER HORST RALF
IPC: C07D319/06 , C12P7/04 , C12P7/22 , C12P7/24 , C12P7/40 , C12P17/00 , C12P17/06 , C12P17/10 , C12P17/12 , C12P17/14 , C12R1/01 , C12R1/06 , C12R1/07 , C12R1/13 , C12R1/15 , C12R1/265 , C12R1/365 , C12R1/44
Abstract: PCT No. PCT/EP94/02071 Sec. 371 Date Dec. 28, 1995 Sec. 102(e) Date Dec. 28, 1995 PCT Filed Jun. 24, 1994 PCT Pub. No. WO95/02061 PCT Pub. Date Jan. 19, 1995A process for the biotechnological preparation of alcohols, aldehydes and carboxylic acids by oxidation of compounds of the formula R1-C(CH3)=CR2R3, where R1, R2 and R3 have the meanings indicated in the description, with the aid of microorganisms is described.\!
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公开(公告)号:AU3694997A
公开(公告)日:1998-02-20
申请号:AU3694997
申请日:1997-07-14
Applicant: BASF AG
Inventor: MACK HELMUT , PFEIFFER THOMAS , SEITZ WERNER , ZIERKE THOMAS , BALKENHOHL FRIEDHELM , LANGE UDO
IPC: C12P17/04 , C07D207/22 , C07D401/12 , C12P17/10
Abstract: PCT No. PCT/EP97/03752 Sec. 371 Date Jan. 22, 1999 Sec. 102(e) Date Jan. 22, 1999 PCT Filed Jul. 14, 1997 PCT Pub. No. WO98/04523 PCT Pub. Date Feb. 5, 19983-Pyrroline-2-carboxylic acid derivatives of the formula I are prepared by eliminating the sulfonic acid residue, with the aid of a base, from a compound of the formula II
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20.
公开(公告)号:CA2170059A1
公开(公告)日:1995-03-30
申请号:CA2170059
申请日:1994-09-16
Applicant: BASF AG
Inventor: BALKENHOHL FRIEDHELM , HAUER BERNHARD , LADNER WOLFGANG , PRESSLER UWE , NUEBLING CHRISTOPH
Abstract: A process for producing optically active primary and secondary amines from the corresponding racemates is characterized in that (a) a racemic amine is enantioselectively acylated in the presence of a hydrolase with an ester whose acid component bears a fluorine, nitrogen, oxygen or sulphur atom at the proximity of the carbonyl carbon atom; (b) the mixture of optically active amine and optically active acylated amine is separated so that an enantiomer of amine is produced; (c) if desired the other enantiomer of the amine is extracted from the acylated amine by amide cleavage.
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