公开(公告)号：DE2551172A1

公开(公告)日：1977-05-26

申请号：DE2551172

申请日：1975-11-14

Applicant: BASF AG

Inventor： HOFFMANN WERNER DIPL CHEM DR ,  HIMMELE WALTER DIPL CHEM DR

IPC: C07C45/49 ,  C07C45/66 ,  C07C49/403 ,  C07C49/613 ,  C07C49/753 ,  C11B9/00 ,  C07C49/48

Abstract: Prepn. of cyclohex-2-en-1-ones having formula (I) (where R1 and R2 each is satd. 1-20C hydrocarbyl or Ph or R1 and R2 are linked to form a 5- or 6-membered cycloalkyl gp. R3 and R4 may be H or non-linked R1 and R2-type gps.). Prepn. comprises hydroformylating a ketone having formula (II), using Rh catalysts, and dehydrating the obtd. formyl derivs., (III), under acid conditions, with ring-closure. (I) are odoriferous materials with a wide range of wood-notes. (I) can also be used as intermediates in prepn. of mono-, sesqui- and diterpenes. E.g. 4-isopropyl-cyclohex-2-en-1-one can be converted to menth-2-en-1-ol, followed by allyl rearrangement and hydrogenation to d,1-menthol. In an example, 4-isopropyl-cyclohex-2-en-1-one was prepd. by (i) hydroformylation of 6-methyl-hept-5-en-2-one to 5-formyl-6-methyl-heptan-2-one and (ii) dehydration and ring-closure with H3PO4.

公开(公告)号：DE2532799A1

公开(公告)日：1977-02-10

申请号：DE2532799

申请日：1975-07-23

Applicant: BASF AG

Inventor： HOFFMANN WERNER DIPL CHEM DR ,  BAUMANN MANFRED DIPL CHEM DR

IPC: C07C45/67 ,  C07C45/68 ,  C07C45/76 ,  C07C49/255 ,  C07C49/20

Abstract: New 7-alkoxy-6-methyl-5-hepten-2-ones RO-CH2-CMe=CH-CH2-CH2-CMeO (I) (where R is Me, Et, n- or iso-C3H7), are perfurmes having fruity, green tones. (I) are also intermediates for 12-alkoxy-3,7,11-trimethyl-dodecatetraenes (IV), useful as perfumes and flavouring materials having an orange-fruity, green note. (I) are prepd. from alkoxyacetones RO-CH2-CO-CH3 (II) first vinylated, or ethynylated and partly hydrogenated. The 1-alkoxy-2-hydroxy-2-methyl-3-butenes obtd., of formula RO-CH2-C(OH)Me-CH=CH2 (III), are then converted to (I).

公开(公告)号：DE2451534A1

公开(公告)日：1976-05-06

申请号：DE2451534

申请日：1974-10-30

Applicant: BASF AG

Inventor： HOFFMANN WERNER DIPL CHEM DR

IPC: C07C49/17

Abstract: High-purity 2-methyl-2-hydroxy-heptanone-6 is produced by converting contaminated 2-methyl-2-hydroxy-heptanone-6 into 2,2,6-trimethyl-2,3-hydro-4-H-pyran by treatment with a non-volatile acid; purifying the pyran; treating the purified pyran with water in the presence of an acid ion-exchanger; and evaporating the resulting aq. soln. to obtain pure 2-methyl-2-hydroxy-heptanone-6, according to the Parent Patent is improved by treating the pyren with water in presence of a catalytic amt. of a medium-strong to strong acid (pref. a strong mineral acid) instead of the acid ion-exchanger used in the Parent Patent.

公开(公告)号：DE3144079A1

公开(公告)日：1983-05-19

申请号：DE3144079

申请日：1981-11-06

Applicant: BASF AG

Inventor： HOFFMANN WERNER DIPL CHEM DR

IPC: A23L27/20 ,  C07C59/215 ,  C07C59/347 ,  C07C69/716 ,  C07D307/33 ,  C07D309/30 ,  C11D3/50 ,  A23L1/226 ,  A61K7/46 ,  C07C121/34 ,  C07D307/30

Abstract: Compounds of the formula in which R , R and R denote hydrogen, a straight-chain or branched alkyl radical having 1 to 4 carbon atoms, R denotes a straight-chain or branched alkyl radical having 1 to 8 carbon atoms, where R and R can also together denote a methylene chain having 3 to 10 carbon atoms and R represents the group -COOR or -CN, where R denotes a hydrogen atom or a straight-chain or branched alkyl group having 1 to 4 carbon atoms, and their use for the preparation of lactones having perfume properties.

公开(公告)号：DE3127242A1

公开(公告)日：1983-01-20

申请号：DE3127242

申请日：1981-07-10

Applicant: BASF AG

Inventor： DEGNER DIETER DIPL CHEM DR ,  HOFFMANN WERNER DIPL CHEM DR ,  THOEMEL FRANK DIPL CHEM DR

IPC: C07D315/00 ,  C25B3/25 ,  C25B3/04

Abstract: Cyclopentadecanolide of the formula I I is prepared by a process wherein 12-oxocyclopentadecanolide of the formula II is reduced electrochemically.

公开(公告)号：DE3116913A1

公开(公告)日：1982-11-18

申请号：DE3116913

申请日：1981-04-29

Applicant: BASF AG

Inventor： THOEMEL FRANK DIPL CHEM DR ,  HOFFMANN WERNER DIPL CHEM DR

IPC: C07C37/06 ,  C07C37/07 ,  C07C39/08 ,  C07C41/00 ,  C07C41/01 ,  C07C43/205 ,  C07C43/23 ,  C07C67/30 ,  C07C69/84 ,  C07C69/88 ,  C07C69/92 ,  C07C255/53 ,  C11B9/00 ,  C07C121/75 ,  A61K7/46

Abstract: A process for the preparation of resorcinol derivatives of the general formula I (I) where R1 is carbalkoxy, nitrile, alkyl or H and R2 to R5 are H or lower alkyl, by reacting the corresponding cyclohexane-1,3-dione (II) with oxygen or an oxygen-containing gas in the presence of a catalytic amount of a copper compound and of from 1 to 10 moles of a hydrogen halide, or from 0.5 to 5 moles of thionyl chloride per mole of II, in an alkanol having from 1 to 6 carbon atoms, tetrahydrofuran or methyl tert.-butyl ether as the solvent, at from 0 DEG to 150 C., without the addition of a significant amount of water to the reaction mixture. Some of the resorcinol derivatives prepared are useful scents with fragrance notes of the character of the odoriferous substance of natural oak moss.

公开(公告)号：DE3114071A1

公开(公告)日：1982-10-28

申请号：DE3114071

申请日：1981-04-08

Applicant: BASF AG

Inventor： JANITSCHKE LOTHAR DIPL CHEM DR ,  HOFFMANN WERNER DIPL CHEM DR ,  ARNOLD LOTHAR DIPL CHEM DR ,  STROEZEL MANFRED ING GRAD ,  SCHEIPER HANS-JUERGEN ING GRAD

IPC: C07C45/00 ,  C07C45/74 ,  C07C49/203 ,  C07C67/00

Abstract: An improved process for the preparation of unsaturated ketones of the general formula I (I) where R1 is -CH3, and R2 and R3 are different and each is H or -CH3, by reacting an aldehyde of the general formula II (II) with a molar excess of acetone or methyl ethyl ketone at an elevated temperature in the presence of an aqueous alkali metal hydroxide solution, wherein (a) all the reactants are mixed thoroughly, (b) the temperature is kept at from 10 to 120 DEG C. above the boiling point of the lowest-boiling component and (c) the pressure is kept at from p to 100 bar, where p is the vapor pressure of the mixture at the reaction temperature. The products methylpseudoionone, dimethylpseudoionone, pseudoirone, methylpseudoirone and dimethylpseudoirone are useful scents and scent intermediates. In addition, pseudoionone is an important intermediate for the industrial preparation of vitamin A, and 6-methyl-hepta-3,5-dien-2-one is a sought-after aromatic.

公开(公告)号：DE3028502A1

公开(公告)日：1982-03-04

申请号：DE3028502

申请日：1980-07-26

Applicant: BASF AG

Inventor： THOEMEL FRANK DIPL CHEM DR ,  HOFFMANN WERNER DIPL CHEM DR ,  DEGNER DIETER DIPL CHEM DR

IPC: A61K8/49 ,  A61Q17/04 ,  C07D307/58 ,  A61K7/42

公开(公告)号：DE3027269A1

公开(公告)日：1982-03-04

申请号：DE3027269

申请日：1980-07-18

Applicant: BASF AG

Inventor： GRAMLICH WALTER DIPL CHEM DR ,  HOFFMANN WERNER DIPL CHEM DR ,  HUPFER LEOPOLD DIPL CHEM DR ,  MEISSNER BERND DIPL CHEM DR ,  PAETSCH JUERGEN DIPL CHEM DR

IPC: C07C29/17 ,  C07C29/38 ,  C07C29/40 ,  C07C31/02 ,  C07C31/125 ,  C07C33/02 ,  C07C33/03 ,  C07C33/04 ,  C07C33/042 ,  C07C33/048 ,  C07C69/145 ,  C11B9/00 ,  C07C33/48 ,  C11D3/50 ,  C11D9/44

Abstract: 3,6-Dimethyl-3-hydroxy-oct-1-ynes and -oct-1-enes and their esters with lower alkanoic acids, of the general formula I (I) where X and Y are H or the two X's and/or the two Y's together are a further bond between the carbon atoms on which they are present, and R is H, -CO-CH3, -CO-C2H5 or -CO-C3H7, their use as scents, and a process for the preparation of 3,6-dimethyl-3-hydroxy-octane. The novel compounds exhibit interesting, predominantly floral, woody, herbal and fruity notes. The alcohols of the formula I are of particular importance because they serve as intermediates for a novel and particularly advantageous method of obtaining 3,6-dimethyl-3-hydroxy-octane, a compound required in large amounts as a fragrance for soaps and detergents.

公开(公告)号：DE3006867A1

公开(公告)日：1981-09-03

申请号：DE3006867

申请日：1980-02-23

Applicant: BASF AG

Inventor： ARNOLD LOTHAR DIPL CHEM DR ,  DEHLER JUERGEN DIPL PHYS DR ,  HOFFMANN WERNER DIPL CHEM DR ,  KROESCHE HENNING DIPL CHEM DR

IPC: B01J23/00 ,  B01J23/44 ,  C07B61/00 ,  C07C45/00 ,  C07C45/62 ,  C07C49/04 ,  C07C67/00