公开(公告)号：DE60220526T2

公开(公告)日：2008-02-07

申请号：DE60220526

申请日：2002-09-09

Applicant: BASF AG

Inventor： WOOD WILLIAM WAKEFIELD ,  KUHN DAVID ,  HU YULIN ,  TECLE BERHANE

IPC: A01N43/90 ,  A01N43/42 ,  A61K31/437 ,  A61P33/00 ,  C07D471/02 ,  C07D491/02 ,  C07D513/04

Abstract: Di- and trifluorosubstituted alkene compounds of formula I wherein X is hydrogen or fluorine; Y is oxygen, NR 1 or S(O) m ; R 1 is hydrogen or C 1 -C 6 -alkyl; m is 0, 1, or 2; A,B,D and E are selected from the following: a) A is N and B, D and E are CR 2 ; or b) B is N and A, D and E are CR 2 ; or c) D is N and A, B, and E are CR 2 ; or d) A and D are N and B and E are CR 2 ; or e) B and E are N and A and D are CR 2 ; R 2 is H, halogen, NH 2 , NO 2 , CN, alkyl, haloalkyl, alkenyl, alkoxy, haloalkoxy, alkylthio, haloalkylthio, alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl, haloalkylsulfonyl, aminosulfonyl, alkoxyalkyl, alkylthioalkyl, alkylsulfinylalkyl, alkylsulfonylalkyl,alkylaminoalkyl, dialkylaminoalkyl, hydroxycarbonyl, or alkoxycarbonyl; or phenyl which may be substituted with halogen, CN, NO 2 , alkyl, haloalkyl, alkoxy, or haloalkoxy; or a 5- to 6-membered heteroaromatic ring system containing 1 to 3 heteroatoms selected from oxygen, sulfur and nitrogen, which may be substituted with halogen, CN, NO 2 , alkyl, haloalkyl, alkoxy, or haloalkoxy; n is 1, 2, 3 or 4, and the agriculturally and/or physiologically tolerable salts thereof, methods for the preparation of compounds I, and compositions and methods for the control of nematodes and arachnids, and for treating, controlling, preventing and protecting warm-blooded animals, fish and humans against infestation and infection by helminths, arachnids and arthropod endo- and ectoparasites.

公开(公告)号：ES2284945T3

公开(公告)日：2007-11-16

申请号：ES02782789

申请日：2002-09-09

Applicant: BASF AG

Inventor： WOOD WILLIAM WAKEFIELD ,  KUHN DAVID ,  HU YULIN ,  TECLE BERHANE

IPC: A01N43/90 ,  A01N43/42 ,  A61K31/437 ,  A61P33/00 ,  C07D471/02 ,  C07D491/02 ,  C07D513/04

Abstract: Compuestos de alqueno di y trisustituidos de fórmula I, en donde X es hidrógeno o fluor; Y es oxígeno, NR1 o S(O)m; R1 es hidrógeno o alquilo C1-C6; m es 0, 1 ó 2; A, B, D y E se seleccionan de lo siguiente: a) A es N y B, D y E son CR2; o d) A y D son N y B y E son CR2, o R2 es hidrógeno, halógeno, amino, nitro, ciano, alquilo C1-C6, haloalquilo C1-C6, alquenilo C1-C6, alcoxi C1-C6, haloalcoxi C1-C6, alquiltio C1-C6, haloalquiltio C1-C6, alquilsulfinilo C1-C6, haloalquilsulfinilo C1-C6, alquilsulfonilo C1-C6, haloalquilsulfonilo C1-C6, aminosulfonilo, alcoxi C1-C6-alquilo C1-C6, alquiltio C1-C6-alquilo C1-C6, alquilsulfinilo C1-C6-alquilo C1-C6, alquilsulfonilo C1-C6-alquilo C1-C6, alquilamino C1-C6-alquilo C1-C6, dialquilamino C1-C6-alquilo C1-C6, hidroxicarbonilo C1-C6, o alcoxicarbonilo C1-C6; o fenilo que pueda ser sustituido con cualquier combinación de 1 a 5 átomos de halógeno, 1 ó 2 grupos ciano, 1 ó 2 grupos nitro, 1 a 3 grupos alquilo C1-C4, 1 a 4 grupos haloalquilo C1-C4, 1 a 3 grupos alcoxi C1-C4 ó 1 a 3 grupos haloalcoxi C1-C4; o un sistema de anillo heteroaromático de 5 a 6 miembros que contiene de 1 a 3 heteroátomos seleccionados de oxígeno, azufre y nitrógeno, que pueden ser sustituidos con cualquier combinación de 1 a 5 átomos de halógeno, 1 ó 2 grupos ciano, 1 ó 2 grupos nitro, 1 a 3 grupos alquilo C1-C4, 1 a 3 grupos haloalquilo C1-C4, 1 a 3 grupos alcoxi C1-C4 ó 1 a 3 grupos haloalcoxi C1-C4; n es 1, 2, 3 ó 4, y las sales de los mismos tolerables fisiológicamente y/o en agricultura.

公开(公告)号：UA79758C2

公开(公告)日：2007-07-25

申请号：UA20040403076

申请日：2002-09-25

Applicant: BASF AG

Inventor： FURCH JOSEPH A ,  KUHN DAVID ,  SZUCS STEPHEN S ,  GU KUN-JIAN ,  VON DEYN WOLFGANG

IPC: A01N25/02 ,  A01N25/08 ,  A01N43/56 ,  A01N47/36 ,  C07D231/12 ,  C07D231/14 ,  C07D231/16 ,  C07D231/18 ,  C07D231/20 ,  C07D231/28 ,  C07D231/38 ,  C07D231/40 ,  C07D401/04

Abstract: Compounds of formula (1), wherein the variables and the index have the following meanings: R1 H, halogen, alkyl, haloalkyl, alkenyl, haloalkenyl, alkylthio, alkoxyalkyl, alkylthioalkyl, or opieonally substituted phenyl; R2 H, halogen, alkyl, haloalkyl, alkenyl, haloalkenyl or optionally substituted phenyl; A H, OH, CN, NO2, halogen, SCN, alkoxy, haloalkoxy, alkenyloxy, alkylthio, haloalkylthio, alkylsulfinyl, alkylsulfonyl, aminothiocarbonyl, hydroxycarbonyl, alkoxycarbonyl, or aminocarbonyl; B H, OH, NH2, CN, NO2, halogen, optionally substituted alkyl, optionally substituted alkoxy, optionally substituted alkenyl, alkenyloxy, alkylthio, haloalkylthio, alkoxythiocarbonylthio, alkoxycarbonylalkoxy, alkoxycarbonylalkylthio, alkylsulfinyl, alkylsulfonyl, aminothiocarbonyl, NR3R4, N=CHOR5, or N=CHNR5; R3, R4 H, alkyl, alkoxycarbonylalkyl, [(alkoxycarbonyl)(alkenyl)]alkyl, alkoxycarbonylalkenyl, alkylcarbonyl, cycloalkylcarbonyl, alkylaminocarbonyl, diaminocarbonyl, alkoxycarbonyl, alkoxyaminosulfonyl, or di(alkoxy)aminosulfonyl; R5 alkyl,haloalkyl, or phenylalkyl; Q H, NO2, halogen, haloalkyl, alkylamino, dialkylamino, alkoxy, haloalkoxy, or alkenyloxy; X H, halogen, haloalkyl, alkoxy or haloalkoxy; Y H, halogen, haloalkyl, alkoxy or haloalkoxy; Z H, halogen, haloalkyl, alkoxy or haloalkoxy; M N or CR6; R6 H, NO2, halogen or haloalkyl; n 0, 1, 2, 3, or 4, with the proviso that, when R1 is hydrogen, n is not zero, processes for the preparation of compounds of formula (I), compositions containing them and their use for the control of insect and acarid pests and for the protection of plants from those pests as well as their use for treating, controlling, preventing and protecting warm-blooded animals and humans against infestation and infection by arachnids and arthropod endo- and ectoparasites. (I)

公开(公告)号：DE60220526D1

公开(公告)日：2007-07-19

申请号：DE60220526

申请日：2002-09-09

Applicant: BASF AG

Inventor： WOOD WILLIAM WAKEFIELD ,  KUHN DAVID ,  HU YULIN ,  TECLE BERHANE

IPC: A01N43/90 ,  A01N43/42 ,  A61K31/437 ,  A61P33/00 ,  C07D471/02 ,  C07D491/02 ,  C07D513/04

Abstract: Di- and trifluorosubstituted alkene compounds of formula I wherein X is hydrogen or fluorine; Y is oxygen, NR 1 or S(O) m ; R 1 is hydrogen or C 1 -C 6 -alkyl; m is 0, 1, or 2; A,B,D and E are selected from the following: a) A is N and B, D and E are CR 2 ; or b) B is N and A, D and E are CR 2 ; or c) D is N and A, B, and E are CR 2 ; or d) A and D are N and B and E are CR 2 ; or e) B and E are N and A and D are CR 2 ; R 2 is H, halogen, NH 2 , NO 2 , CN, alkyl, haloalkyl, alkenyl, alkoxy, haloalkoxy, alkylthio, haloalkylthio, alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl, haloalkylsulfonyl, aminosulfonyl, alkoxyalkyl, alkylthioalkyl, alkylsulfinylalkyl, alkylsulfonylalkyl,alkylaminoalkyl, dialkylaminoalkyl, hydroxycarbonyl, or alkoxycarbonyl; or phenyl which may be substituted with halogen, CN, NO 2 , alkyl, haloalkyl, alkoxy, or haloalkoxy; or a 5- to 6-membered heteroaromatic ring system containing 1 to 3 heteroatoms selected from oxygen, sulfur and nitrogen, which may be substituted with halogen, CN, NO 2 , alkyl, haloalkyl, alkoxy, or haloalkoxy; n is 1, 2, 3 or 4, and the agriculturally and/or physiologically tolerable salts thereof, methods for the preparation of compounds I, and compositions and methods for the control of nematodes and arachnids, and for treating, controlling, preventing and protecting warm-blooded animals, fish and humans against infestation and infection by helminths, arachnids and arthropod endo- and ectoparasites.

公开(公告)号：PL370353A1

公开(公告)日：2005-05-16

申请号：PL37035302

申请日：2002-09-25

Applicant: BASF AG

Inventor： FURCH JOSEPH A ,  KUHN DAVID ,  SZUCS STEPHEN S ,  GU KUN-JIAN ,  VON DEYN WOLFGANG

IPC: A01N25/02 ,  A01N25/08 ,  A01N43/56 ,  A01N47/36 ,  C07D231/12 ,  C07D231/14 ,  C07D231/16 ,  C07D231/18 ,  C07D231/20 ,  C07D231/28 ,  C07D231/38 ,  C07D231/40 ,  C07D401/04 ,  A61K31/415

Abstract: Compounds of formula (I), wherein the variables and the index have the following meanings: R H, halogen, alkyl, haloalkyl, alkenyl, haloalkenyl, alkylthio, alkoxyalkyl, alkylthioalkyl, or optionally substituted phenyl; R H, halogen, alkyl, haloalkyl, alkenyl, haloalkenyl or optionally substituted phenyl; A H, OH, CN, NO2, halogen, SCN, alkoxy, haloalkoxy, alkenyloxy, alkylthio, haloalkylthio, alkylsulfinyl, alkylsulfonyl, aminothiocarbonyl, hydroxycarbonyl, alkoxycarbonyl, or aminocarbonyl; B H, OH, NH2, CN, NO2, halogen, optionally substituted alkyl, optionally substituted alkoxy, optionally substituted alkenyl, alkenyloxy, alkylthio, haloalkylthio, alkoxythiocarbonylthio, alkoxycarbonylalkoxy, alkoxycarbonylalkylthio, alkylsulfinyl, alkylsulfonyl, aminothiocarbonyl, NR R , N=CHOR , or N=CHNR ; R , R H, alkyl, alkoxycarbonylalkyl, [(alkoxycarbonyl)(alkenyl)]alkyl, alkoxycarbonylalkenyl, alkylcarbonyl, cycloalkylcarbonyl, alkylaminocarbonyl, diaminocarbonyl, alkoxycarbonyl, alkoxyaminosulfonyl, or di(alkoxy)aminosulfonyl; R alkyl, haloalkyl, or phenylalkyl; Q H, NO2, halogen, haloalkyl, alkylamino, dialkylamino, alkoxy, haloalkoxy, or alkenyloxy; X H, halogen, haloalkyl, alkoxy or haloalkoxy; Y H, halogen, haloalkyl, alkoxy or haloalkoxy; Z H, halogen, haloalkyl, alkoxy or haloalkoxy; M N or CR ; R H, NO2, halogen or haloalkyl; n 0, 1, 2, 3, or 4, with the proviso that, when R is hydrogen, n is not zero, processes for the preparation of compounds of formula (I), compositions containing them and their use for the control of insect and acarid pests and for the protection of plants from those pests as well as their use for treating, controlling, preventing and protecting warm-blooded animals and humans against infestation and infection by arachnids and arthropod endo-and ectoparasites.

公开(公告)号：BR0212243A

公开(公告)日：2004-10-05

申请号：BR0212243

申请日：2002-09-09

Applicant: BASF AG

Inventor： WOOD WILLIAM WAKEFIELD ,  KUHN DAVID ,  HU YULIN ,  TECLE BERHANE

IPC: A01N43/42 ,  A01N43/90 ,  A61K31/437 ,  A61P33/00 ,  C07D471/02 ,  C07D491/02 ,  C07D513/04

Abstract: Di- and trifluorosubstituted alkene compounds of formula I wherein X is hydrogen or fluorine; Y is oxygen, NR 1 or S(O) m ; R 1 is hydrogen or C 1 -C 6 -alkyl; m is 0, 1, or 2; A,B,D and E are selected from the following: a) A is N and B, D and E are CR 2 ; or b) B is N and A, D and E are CR 2 ; or c) D is N and A, B, and E are CR 2 ; or d) A and D are N and B and E are CR 2 ; or e) B and E are N and A and D are CR 2 ; R 2 is H, halogen, NH 2 , NO 2 , CN, alkyl, haloalkyl, alkenyl, alkoxy, haloalkoxy, alkylthio, haloalkylthio, alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl, haloalkylsulfonyl, aminosulfonyl, alkoxyalkyl, alkylthioalkyl, alkylsulfinylalkyl, alkylsulfonylalkyl,alkylaminoalkyl, dialkylaminoalkyl, hydroxycarbonyl, or alkoxycarbonyl; or phenyl which may be substituted with halogen, CN, NO 2 , alkyl, haloalkyl, alkoxy, or haloalkoxy; or a 5- to 6-membered heteroaromatic ring system containing 1 to 3 heteroatoms selected from oxygen, sulfur and nitrogen, which may be substituted with halogen, CN, NO 2 , alkyl, haloalkyl, alkoxy, or haloalkoxy; n is 1, 2, 3 or 4, and the agriculturally and/or physiologically tolerable salts thereof, methods for the preparation of compounds I, and compositions and methods for the control of nematodes and arachnids, and for treating, controlling, preventing and protecting warm-blooded animals, fish and humans against infestation and infection by helminths, arachnids and arthropod endo- and ectoparasites.