公开(公告)号：BG101079A

公开(公告)日：1997-09-30

申请号：BG10107996

申请日：1996-12-28

Applicant: BASF AG

Inventor： BAYER HERBERT ,  ISAK HEINZ ,  WINGERT HORST ,  SAUTER HUBERT ,  KEIL MICHAEL ,  NETT MARKUS ,  BENOIT REMY ,  MUELLER RUTH

IPC: C07C67/22 ,  C07C69/716 ,  C07C69/738 ,  C07C235/78 ,  C07C249/08 ,  C07C249/12 ,  C07C251/48 ,  C07C251/60 ,  C07C255/41 ,  C07C255/62 ,  C07D249/12 ,  C07D521/00

Abstract: The invention concerns a method of preparing -methoxyiminocarboxylic acid methylamides of formula X=nitro, trifluoromethyl, halogen, alkyl or alkoxy; n=0,1,2,3 or 4; Y=an organic carbon group) by the Pinner reaction of a cyanoketone of formula with an alcohol, followed by reaction of the ester of formula formed in the Pinner reaction with hydroxylamine to give an oxime of formula methylation of compound of formula V to give an oxime ether of formula and subsequent reaction of compound of formula VI with methylamine.

公开(公告)号：ZA954825B

公开(公告)日：1996-12-12

申请号：ZA954825

申请日：1995-06-12

Applicant: BASF AG

Inventor： BAYER HERBERT ,  ISAK HEINZ ,  WINGERT HORST ,  SAUTER HUBERT ,  KEIL MICHAEL ,  NETT MARKUS ,  BENOIT REMY ,  MUELLER RUTH

IPC: C07C67/22 ,  C07C69/716 ,  C07C69/738 ,  C07C235/78 ,  C07C249/08 ,  C07C249/12 ,  C07C251/48 ,  C07C251/60 ,  C07C255/41 ,  C07C255/62 ,  C07D249/12 ,  C07D521/00 ,  C07C

Abstract: A process and intermediates for preparing alpha -methoxyiminocarboxylic acid methylamides (I) by Pinner reaction of a cyanoketone (II) with an alcohol and subsequent reaction of the resulting ester (IV) with hydroxylamine to give the oxime (V), methylation of (V) to give the oxime ether (VI) and subsequent reaction of (VI) with methylamine: +TR X = nitro, trifluoromethyl, halogen, alkyl or alkoxy; n = 0, 1, 2, 3 or 4; Y = a C-organic radical.

公开(公告)号：CZ297235B6

公开(公告)日：2006-10-11

申请号：CZ357896

申请日：1995-05-26

Applicant: BASF AG

Inventor： BAYER HERBERT ,  ISAK HEINZ ,  WINGERT HORST ,  SAUTER HUBERT ,  KEIL MICHAEL ,  NETT MARKUS ,  BENOIT REMY ,  MUELLER RUTH

IPC: C07C67/22 ,  C07C69/716 ,  C07C69/738 ,  C07C235/78 ,  C07C249/08 ,  C07C249/12 ,  C07C251/48 ,  C07C251/60 ,  C07C255/41 ,  C07C255/62 ,  C07D249/12 ,  C07D521/00

Abstract: Zpusob prípravy derivátu methylamidu .alfa.-methoxyiminokarboxylové kyseliny obecného vzorce I, kdeznamená X NO.sub.2.n., CF.sub.3.n., halogenu, C.sub.1-4.n.alkyl nebo C.sub.1-4.n.alkoxy, n celé císlo 1 az 4, pricemz skupiny symbolu X mohou být stejné nebo ruzné, pokud n znamená vetsí císlo nez 1 a Y uhlíkovou organickou skupinu, pri kterém se Pinnerovou reakcí nechává reagovat acylkyanid obecného vzorce II s alkoholem obecného vzorce ROH, jehoz teplota varu je vyssí nez 75 .degree.C, a následne se nechá reagovat Pinnerovou reakcí vytvorený ester obecného vzorce IV a) s hydroxylaminem za vzniku oximu obecného vzorce V, který se methyluje naoximether obecného vzorce VI, nebo b) s O-methylhydroxylaminem na oximether obecného vzorce VI a následne se nechá reagovat oximether obecného vzorceVI s methylaminem, pricemz jednotlivé symboly mají shora uvedený význam a R znamená zbytek alkoholu, jehoz teplota varu je vyssí nez 75 .degree.C. Dále jsou popsány meziprodukty pro tuto reakci obecných vzorcu IV A, V A a VI A, kde R.sup.1.n. znamená atom halogenu nebo OH, R znamená zbytek alkoholuR-OH, jehoz teplota varu je vyssí nez 75 .degree.C, X znamená NO.sub.2.n., CF.sub.3.n., atom halogenu, C.sub.1-4.n.alkyl nebo C.sub.1-4.n.alkoxy, n znamená celé císlo 1 az 4, pricemz skupiny symbolu X mohou být stejné nebo ruzné, pokud n je vetsí nez 1.

公开(公告)号：SK283068B6

公开(公告)日：2003-02-04

申请号：SK157596

申请日：1995-05-26

Applicant: BASF AG

Inventor： BAYER HERBERT ,  ISAK HEINZ ,  WINGERT HORST ,  SAUTER HUBERT ,  KEIL MICHAEL ,  NETT MARKUS ,  BENOIT REMY ,  MULLER RUTH

IPC: C07C67/22 ,  C07C69/716 ,  C07C69/738 ,  C07C235/78 ,  C07C249/08 ,  C07C249/12 ,  C07C251/48 ,  C07C251/60 ,  C07C255/41 ,  C07C255/62 ,  C07D249/12 ,  C07D521/00

Abstract: The invention concerns a method of preparing 'alpha'-methoxyiminocarboxylic acid methylamides of formula (I) (X = nitro, trifluoromethyl, halogen, alkyl or alkoxy; n = 0, 1, 2, 3 or 4; Y = an organic carbon group) by the Pinner reaction of a cyanoketone of formula (II) with an alcohol, followed by reaction of the ester of formula (IV) formed in the Pinner reaction with hydroxylamine to give an oxime of formula (V), methylation of (V) to give an oxime ether of formula (VI) and subsequent reaction of (VI) with methylamine. The invention also concerns the intermediates used in the method.

公开(公告)号：HU219195B

公开(公告)日：2001-03-28

申请号：HU9603401

申请日：1995-05-26

Applicant: BASF AG

Inventor： BAYER HERBERT ,  BENOIT REMY ,  ISAK HEINZ ,  KEIL MICHAEL ,  MUELLER RUTH ,  NETT MARKUS ,  SAUTER HUBERT ,  WINGERT HORST

IPC: C07C67/22 ,  C07C69/716 ,  C07C69/738 ,  C07C235/78 ,  C07C249/08 ,  C07C249/12 ,  C07C251/48 ,  C07C251/60 ,  C07C255/41 ,  C07C255/62 ,  C07D249/12 ,  C07D521/00

Abstract: A process and intermediates for preparing alpha -methoxyiminocarboxylic acid methylamides (I) by Pinner reaction of a cyanoketone (II) with an alcohol and subsequent reaction of the resulting ester (IV) with hydroxylamine to give the oxime (V), methylation of (V) to give the oxime ether (VI) and subsequent reaction of (VI) with methylamine: +TR X = nitro, trifluoromethyl, halogen, alkyl or alkoxy; n = 0, 1, 2, 3 or 4; Y = a C-organic radical.

公开(公告)号：NO307333B1

公开(公告)日：2000-03-20

申请号：NO965259

申请日：1996-12-09

Applicant: BASF AG

Inventor： BAYER HERBERT ,  ISAK HEINZ ,  WINGERT HORST ,  SAUTER HUBERT ,  KEIL MICHAEL ,  NETT MARKUS ,  BENOIT REMY ,  MUELLER RUTH

IPC: C07C67/22 ,  C07C69/716 ,  C07C69/738 ,  C07C235/78 ,  C07C249/08 ,  C07C249/12 ,  C07C251/48 ,  C07C251/60 ,  C07C255/41 ,  C07C255/62 ,  C07D249/12 ,  C07D521/00

Abstract: A process and intermediates for preparing alpha -methoxyiminocarboxylic acid methylamides (I) by Pinner reaction of a cyanoketone (II) with an alcohol and subsequent reaction of the resulting ester (IV) with hydroxylamine to give the oxime (V), methylation of (V) to give the oxime ether (VI) and subsequent reaction of (VI) with methylamine: +TR X = nitro, trifluoromethyl, halogen, alkyl or alkoxy; n = 0, 1, 2, 3 or 4; Y = a C-organic radical.

公开(公告)号：NZ287862A

公开(公告)日：1999-02-25

申请号：NZ28786295

申请日：1995-05-26

Applicant: BASF AG

Inventor： BAYER HERBERT ,  ISAK HEINZ ,  WINGERT HORST ,  SAUTER HUBERT ,  KEIL MICHAEL ,  NETT MARKUS ,  BENOIT REMY ,  MULLER RUTH

IPC: C07C67/22 ,  C07C69/716 ,  C07C69/738 ,  C07C235/78 ,  C07C249/08 ,  C07C249/12 ,  C07C251/48 ,  C07C251/60 ,  C07C255/41 ,  C07C255/62 ,  C07D249/12 ,  C07D521/00 ,  C07C251/38 ,  C07C251/34

Abstract: A process and intermediates for preparing alpha -methoxyiminocarboxylic acid methylamides (I) by Pinner reaction of a cyanoketone (II) with an alcohol and subsequent reaction of the resulting ester (IV) with hydroxylamine to give the oxime (V), methylation of (V) to give the oxime ether (VI) and subsequent reaction of (VI) with methylamine: +TR X = nitro, trifluoromethyl, halogen, alkyl or alkoxy; n = 0, 1, 2, 3 or 4; Y = a C-organic radical.

公开(公告)号：FI964901A0

公开(公告)日：1996-12-05

申请号：FI964901

申请日：1996-12-05

Applicant: BASF AG

Inventor： BAYER HERBERT ,  ISAK HEINZ ,  WINGERT HORST ,  SAUTER HUBERT ,  KEIL MICHAEL ,  NETT MARKUS ,  BENOIT REMY ,  MUELLER RUTH

IPC: C07C67/22 ,  C07C69/716 ,  C07C69/738 ,  C07C235/78 ,  C07C249/08 ,  C07C249/12 ,  C07C251/48 ,  C07C251/60 ,  C07C255/41 ,  C07C255/62 ,  C07D249/12 ,  C07D521/00 ,  C07C

Abstract: A process and intermediates for preparing alpha -methoxyiminocarboxylic acid methylamides (I) by Pinner reaction of a cyanoketone (II) with an alcohol and subsequent reaction of the resulting ester (IV) with hydroxylamine to give the oxime (V), methylation of (V) to give the oxime ether (VI) and subsequent reaction of (VI) with methylamine: +TR X = nitro, trifluoromethyl, halogen, alkyl or alkoxy; n = 0, 1, 2, 3 or 4; Y = a C-organic radical.

公开(公告)号：CA2192594C

公开(公告)日：2007-02-06

申请号：CA2192594

申请日：1995-05-26

Applicant: BASF AG

Inventor： BAYER HERBERT ,  ISAK HEINZ ,  WINGERT HORST ,  SAUTER HUBERT ,  KEIL MICHAEL ,  NETT MARKUS ,  BENOIT REMY ,  MULLER RUTH

IPC: C07C251/48 ,  C07C67/22 ,  C07C69/716 ,  C07C69/738 ,  C07C235/78 ,  C07C249/08 ,  C07C249/12 ,  C07C251/58 ,  C07C251/60 ,  C07C253/30 ,  C07C255/41 ,  C07C255/62 ,  C07C255/64 ,  C07C315/04 ,  C07C317/28 ,  C07C319/20 ,  C07D209/48 ,  C07D231/22 ,  C07D249/12 ,  C07D277/34 ,  C07D521/00

Abstract: The invention concerns a method of preparing .alpha.-methoxyiminocarboxylic acid methylamides of formula (I)(X = nitro, trifluoromet hyl, halogen, alkyl or alkoxy; n = 0, 1, 2, 3 or 4; Y = an organic carbon group) by the Pinner reaction of cyanoketone of formula (II) wi th an alcohol, followed by reaction of the ester of formula (IV) formed in the Pin ner reaction with hydroxylamine to give an oxime of form ula (V), methylation of (V) to give an oxime ether of formula (VI) and subsequen t reaction of (VI) with methylamine. The invention also concerns the intermediates used in the method.

公开(公告)号：BG63115B1

公开(公告)日：2001-04-30

申请号：BG10107996

申请日：1996-12-28

Applicant: BASF AG

Inventor： BAYER HERBERT ,  ISAK HEINZ ,  WINGERT HORST ,  SAUTER HUBERT ,  KEIL MICHAEL ,  NETT MARKUS ,  BENOIT REMY ,  MUELLER RUTH

IPC: C07C67/22 ,  C07C69/716 ,  C07C69/738 ,  C07C235/78 ,  C07C249/08 ,  C07C249/12 ,  C07C251/48 ,  C07C251/60 ,  C07C255/41 ,  C07C255/62 ,  C07D249/12 ,  C07D521/00 ,  C07D249/02

Abstract: The invention concerns a method of preparing alpha-methoxyiminocarboxylic acid methylamides of formula X=nitro, trifluoromethyl, halogen, alkyl or alkoxy; n=0,1,2,3 or 4; Y=an organic carbon group) by the Pinner reaction of a cyanoketone of formula with an alcohol, followed by reaction of the ester of formula formed in the Pinner reaction with hydroxylamine to give an oxime of formula methylation of compound of formula V to give an oxime ether of formula and subsequent reaction of compound of formula VI with methylamine. 10 claims