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公开(公告)号:SK15952001A3
公开(公告)日:2002-08-06
申请号:SK15952001
申请日:2000-05-03
Applicant: BASF AG
Inventor: LUBISCH WILFRIED , SADOWSKI JENS , KOCK MICHAEL , HOGER THOMAS
IPC: C07D237/32 , A61K31/502 , A61P1/10 , A61P9/00 , A61P9/10 , A61P13/12 , A61P17/02 , A61P19/02 , A61P25/00 , A61P25/08 , A61P25/10 , A61P25/12 , A61P25/14 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P35/04 , A61P37/00 , A61P41/00 , A61P43/00 , C07D401/12 , C07D403/12 , A61K31/00
Abstract: The present invention relates to the use of phthalazine derivatives as inhibitors of the enzyme poly(ADP-ribose) polymerase or PARP (EC 2.4.2.30), to the use as inhibitors of PARP-homologous enzymes and, in particular, these phthalazine derivatives also show a selective inhibition of PARP-homologous enzymes.
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公开(公告)号:BR0010428A
公开(公告)日:2002-04-30
申请号:BR0010428
申请日:2000-05-03
Applicant: BASF AG
Inventor: LUBISCH WILFRIED , SADOWSKI JENS , KOCK MICHAEL , HOEGER THOMAS
IPC: C07D237/32 , A61K31/502 , A61P1/10 , A61P9/00 , A61P9/10 , A61P13/12 , A61P17/02 , A61P19/02 , A61P25/00 , A61P25/08 , A61P25/10 , A61P25/12 , A61P25/14 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P35/04 , A61P37/00 , A61P41/00 , A61P43/00 , C07D401/12 , C07D403/12 , A61K31/00
Abstract: The present invention relates to the use of phthalazine derivatives as inhibitors of the enzyme poly(ADP-ribose) polymerase or PARP (EC 2.4.2.30), to the use as inhibitors of PARP-homologous enzymes and, in particular, these phthalazine derivatives also show a selective inhibition of PARP-homologous enzymes.
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公开(公告)号:AU6990000A
公开(公告)日:2001-03-05
申请号:AU6990000
申请日:2000-08-01
Applicant: BASF AG
Inventor: KLING ANDREAS , GENESTE HERVE , LANGE UDO , LAUTERBACH ARNULF , GRAEF CLAUDIA ISABELLA , SUBKOWSKI THOMAS , HOLZENKAMP UTA , MACK HELMUT , SADOWSKI JENS , HORNBERGER WILFRIED , LAUX VOLKER
IPC: A61K31/4402 , A61K31/55 , A61K31/5513 , A61P3/14 , A61P5/18 , A61P7/02 , A61P9/00 , A61P9/08 , A61P9/10 , A61P9/12 , A61P9/14 , A61P13/12 , A61P17/02 , A61P17/06 , A61P19/00 , A61P19/08 , A61P19/10 , A61P29/00 , A61P31/04 , A61P31/12 , A61P33/00 , A61P35/00 , A61P35/04 , A61P43/00 , C07D213/74 , C07D223/20 , C07D243/38 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D409/12 , C07D409/14 , C07D417/06 , C07D417/12 , C07D417/14 , C07D471/04 , C07D495/04 , C07D495/14 , C07D243/00
Abstract: The invention relates to novel compounds which bind to integrin receptors, and to the preparation thereof and the use thereof as drugs.
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公开(公告)号:CA2368049A1
公开(公告)日:2000-10-19
申请号:CA2368049
申请日:2000-03-29
Applicant: BASF AG
Inventor: HORNBERGER WILFRIED , ZECHEL JOHANN-CHRISTIAN , KLING ANDREAS , GENESTE HERVE , LANGE UDO , LAUTERBACH ARNULF , GRAEF CLAUDIA ISABELLA , SUBKOWSKI THOMAS , SADOWSKI JENS
IPC: C07D239/36 , A61K31/505 , A61K45/00 , A61K45/06 , A61P3/14 , A61P7/02 , A61P9/10 , A61P9/12 , A61P13/12 , A61P17/02 , A61P17/06 , A61P19/08 , A61P19/10 , A61P29/00 , A61P31/04 , A61P31/12 , A61P33/00 , A61P35/00 , C07D239/34 , C07D239/60 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/04 , C07D405/14 , C07D409/14 , C07D417/12 , C07D417/14 , C07D471/04 , C07D403/04 , C07D239/46
Abstract: The invention relates to novel compounds that bind to integrin receptor ligands. The invention also relates to the production thereof, to their use as integrin receptor ligands and to their use for treating diseases, to pharmaceutical preparations that contain said compounds and to pharmaceutica l preparations that contain at least one additional active compound.
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公开(公告)号:SK2002002A3
公开(公告)日:2002-11-06
申请号:SK2002002
申请日:2000-08-01
Applicant: BASF AG
Inventor: KLING ANDREAS , GENESTE HERVE , LANGE UDO , LAUTERBACH ARNULF , GRAEF CLAUDIA ISABELLA , SUBKOWSKI THOMAS , HOLZENKAMP UTA , MACK HELMUT , SADOWSKI JENS , HORNBERGER WILFRIED , LAUX VOLKER
IPC: A61K31/4402 , A61K31/55 , A61K31/5513 , A61P3/14 , A61P5/18 , A61P7/02 , A61P9/00 , A61P9/08 , A61P9/10 , A61P9/12 , A61P9/14 , A61P13/12 , A61P17/02 , A61P17/06 , A61P19/00 , A61P19/08 , A61P19/10 , A61P29/00 , A61P31/04 , A61P31/12 , A61P33/00 , A61P35/00 , A61P35/04 , A61P43/00 , C07D213/74 , C07D223/20 , C07D243/38 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D409/12 , C07D409/14 , C07D417/06 , C07D417/12 , C07D417/14 , C07D471/04 , C07D495/04 , C07D495/14 , C07D213/73 , C07D491/04
Abstract: The invention relates to novel compounds which bind to integrin receptors, and to the preparation thereof and the use thereof as drugs.
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公开(公告)号:SK14102001A3
公开(公告)日:2002-07-02
申请号:SK14102001
申请日:2000-03-29
Applicant: BASF AG
Inventor: ZECHEL JOHANN-CHRISTIAN , KLING ANDREAS , GENESTE HERVE , LANGE UDO , LAUTERBACH ARNULF , GRAEF CLAUDIA ISABELLA , SUBKOWSKI THOMAS , SADOWSKI JENS , HORNBERGER WILFRIED
IPC: A61K31/505 , A61K45/00 , A61K45/06 , A61P3/14 , A61P7/02 , A61P9/10 , A61P9/12 , A61P13/12 , A61P17/02 , A61P17/06 , A61P19/08 , A61P19/10 , C07D239/36 , A61P29/00 , A61P31/04 , A61P31/12 , A61P33/00 , A61P35/00 , C07D239/34 , C07D239/60 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/04 , C07D405/14 , C07D409/14 , C07D417/12 , C07D417/14 , C07D239/46 , C07D403/04
Abstract: The invention relates to novel compounds which bind to integrin receptors, to their preparation, to their use as integrin receptor ligands and for treating diseases, to pharmaceutical preparations comprising these compounds, and to pharmaceutical preparations comprising at least one other active compound.
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公开(公告)号:BR0013265A
公开(公告)日:2002-05-14
申请号:BR0013265
申请日:2000-08-01
Applicant: BASF AG
Inventor: KLING ANDREAS , GENESTE HERVE , LANGE UDO , LAUTERBACH ARNULF , GRAEF CLAUDIA ISABELLA , SUBKOWSKI THOMAS , HOLZENKAMP UTA , MACK HELMUT , SADOWSKI JENS , HORNBERGER WILFRIED , LAUX VOLKER
IPC: A61K31/4402 , A61K31/55 , A61K31/5513 , A61P3/14 , A61P5/18 , A61P7/02 , A61P9/00 , A61P9/08 , A61P9/10 , A61P9/12 , A61P9/14 , A61P13/12 , A61P17/02 , A61P17/06 , A61P19/00 , A61P19/08 , A61P19/10 , A61P29/00 , A61P31/04 , A61P31/12 , A61P33/00 , A61P35/00 , A61P35/04 , A61P43/00 , C07D213/74 , C07D223/20 , C07D243/38 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D409/12 , C07D409/14 , C07D417/06 , C07D417/12 , C07D417/14 , C07D471/04 , C07D495/04 , C07D495/14 , C07D243/00
Abstract: The invention relates to novel compounds which bind to integrin receptors, and to the preparation thereof and the use thereof as drugs.
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公开(公告)号:BR0009739A
公开(公告)日:2002-04-09
申请号:BR0009739
申请日:2000-03-29
Applicant: BASF AG
Inventor: ZECHEL JOHANN-CHRISTIAN , KLING ANDREAS , GENESTE HERVE , LANGE UDO , LAUTERBACH ARNULF , GRAEF CLAUDIA ISABELLA , SUBKOWSKI THOMAS , SADOWSKI JENS , HORNBERGER WILFRIED
IPC: C07D239/36 , A61K31/505 , A61K45/00 , A61K45/06 , A61P3/14 , A61P7/02 , A61P9/10 , A61P9/12 , A61P13/12 , A61P17/02 , A61P17/06 , A61P19/08 , A61P19/10 , A61P29/00 , A61P31/04 , A61P31/12 , A61P33/00 , A61P35/00 , C07D239/34 , C07D239/60 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/04 , C07D405/14 , C07D409/14 , C07D417/12 , C07D417/14
Abstract: The invention relates to novel compounds which bind to integrin receptors, to their preparation, to their use as integrin receptor ligands and for treating diseases, to pharmaceutical preparations comprising these compounds, and to pharmaceutical preparations comprising at least one other active compound.
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公开(公告)号:NO20014961A
公开(公告)日:2001-11-07
申请号:NO20014961
申请日:2001-10-12
Applicant: BASF AG
Inventor: ZECHEL JOHANN-CHRISTIAN , KLING ANDREAS , GENESTE HERVE , LANGE UDO , LAUTERBACH ARNULF , GRAEF CLAUDIA ISABELLA , SUBKOWSKI THOMAS , SADOWSKI JENS , HORNBERGER WILFRIED
IPC: C07D239/36 , A61K31/505 , A61K45/00 , A61K45/06 , A61P3/14 , A61P7/02 , A61P9/10 , A61P9/12 , A61P13/12 , A61P17/02 , A61P17/06 , A61P19/08 , A61P19/10 , A61P29/00 , A61P31/04 , A61P31/12 , A61P33/00 , A61P35/00 , C07D239/34 , C07D239/60 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/04 , C07D405/14 , C07D409/14 , C07D417/12 , C07D417/14 , C07D233/54
CPC classification number: C07D405/14 , A61K45/06 , C07D239/34 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/04 , C07D409/14 , C07D417/12 , C07D417/14
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公开(公告)号:AU4112900A
公开(公告)日:2000-11-14
申请号:AU4112900
申请日:2000-03-29
Applicant: BASF AG
Inventor: ZECHEL JOHANN-CHRISTIAN , KLING ANDREAS , GENESTE HERVE , LANGE UDO , LAUTERBACH ARNULF , GRAEF CLAUDIA ISABELLA , SUBKOWSKI THOMAS , SADOWSKI JENS , HORNBERGER WILFRIED
IPC: C07D239/36 , A61K31/505 , A61K45/00 , A61K45/06 , A61P3/14 , A61P7/02 , A61P9/10 , A61P9/12 , A61P13/12 , A61P17/02 , A61P17/06 , A61P19/08 , A61P19/10 , A61P29/00 , A61P31/04 , A61P31/12 , A61P33/00 , A61P35/00 , C07D239/34 , C07D239/60 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/04 , C07D405/14 , C07D409/14 , C07D417/12 , C07D417/14
Abstract: The invention relates to novel compounds which bind to integrin receptors, to their preparation, to their use as integrin receptor ligands and for treating diseases, to pharmaceutical preparations comprising these compounds, and to pharmaceutical preparations comprising at least one other active compound.
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