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公开(公告)号：EP0870013A4
公开(公告)日：2003-02-05
申请号：EP97911624
申请日：1997-10-03
Applicant: BAXTER INT
Inventor： HERMAN ROBERT E , CHAPMAN JOHN , CHONG-SON SUN , MATHIAS JEAN M , MAYAUDON VERONIQUE , DE GHELDERE SERGE , BISCHOF DANIEL F
CPC classification number: A61L2/0011 , A61K35/16 , A61L2/022 , A61L2/08 , Y10S435/975
Abstract: Systems and methods treat plasma carrying contaminants and cellular matter that are capable of entraining contaminants. The systems and methods separate cellular matter from the plasma by filtration, thereby removing contaminants entrained within the cellular matter. The system and methods add to the plasma a photoactive material. The systems and methods emit radiation at a selected wavelength into the plasma to activate the photoactive material and thereby eradicate the contaminant that is free of entrainment by cellular matter.
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12.发明公开SYSTEMS AND METHODS FOR ON-LINE FINISHING OF CELLULAR BLOOD PRODUCTS LIKE PLATELETS HARVESTED FOR THERAPEUTIC PURPOSES 失效系统和方法血细胞成分的ON-LINE的治疗，例如 用于治疗目的的血小板采取
公开(公告)号：EP0822845A4
公开(公告)日：1999-12-01
申请号：EP97904262
申请日：1997-02-10
Applicant: BAXTER INT
Inventor： BISCHOF DANIEL F
CPC classification number: A61M1/3693 , A61M1/3696 , A61M2202/0427 , A61M2202/0439 , A61M2202/0071 , A61M2202/0057
Abstract: Blood processing systems and methods establish on-line communication between a container and a source of blood containing leukocytes and platelets, such as a human donor. The systems and methods create a centrifugal field (14) between the source of blood and the container that separates from the blood an unfinished suspension of platelets having a first physiologic characteristic different than the desired physiologic characteristic. The systems and methods pump the unfinished platelet suspension outside the centrifugal field through a finishing device (24). The finishing device (24) changes the first physiologic characteristic to the desired physiological characteristic, thereby creating the finished platelet suspension. The system and methods convey the finished platelet suspension from the finishing device directly into the container. The systems and methods function without interrupting the on-line communication between the container and the source of blood.
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13.发明专利
公开(公告)号：ES2278414T3
公开(公告)日：2007-08-01
申请号：ES98934139
申请日：1998-06-22
Applicant: BAXTER INT
Inventor： MIN KYUNGYOON , BROWN RICHARD I , BISCHOF DANIEL F , CORK WILLIAM H , CANTU ROBERT J
Abstract: Sistema de separación sanguínea que funciona en un primer modo que sirve para hacer penetrar sangre entera en la zona de entrada (48) de una cámara (38) de tratamiento sanguíneo para separarla por centrifugación en glóbulos rojos concentrados, en plasma y en una interfaz que lleva células mononucleares, entre los glóbulos rojos concentrados y el plasma. Este sistema suprime los glóbulos rojos concentrados y el plasma desde la cámara (38), a la vez que conserva la interfaz en el interior de la cámara (38). Este sistema funciona en un segundo modo para suprimir la interfaz desde la cámara (38) introduciendo los glóbulos rojos concentrados en la zona de entrada (48). Un trayecto de salida (48) transporta la interfaz suprimida fuera de la cámara (38). Este trayecto de salida (46) comprende un primer elemento de detección (OS) que sirve para localizar las células mononucleares en la interfaz suprimida y para producir una salida detectada en el momento de la localización de las células mononucleares.
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公开(公告)号：BR0314613A
公开(公告)日：2005-07-26
申请号：BR0314613
申请日：2003-09-24
Applicant: BAXTER INT , CERUS CORP
Inventor： METZEL PEYTON S , BISCHOF DANIEL F , MOORE JOSEPH S , DING YUANPANG SAMUEL , HERMAN ROBERT E , MAYAUDON VERONIQUE , SOUDANT GREGORY , LECOUR DANIEL , BRIERE YVON , DIMINO GEORGE D , HEI DEREK J , LAIRD JAMES , MOHIUDDIN MAHMOOD
Abstract: Apparatus, systems and methods are disclosed for treating a biological fluid with light. A disposable fluid processing set including integrally connected containers and tubing and a holder or organizer for receiving at least some of the containers and tubing are disclosed.
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公开(公告)号：CA2208051C
公开(公告)日：2005-04-12
申请号：CA2208051
申请日：1996-11-26
Applicant: BAXTER INT
Inventor： SUN CHONG-SON , CHAPMAN JOHN , BISCHOF DANIEL F
IPC: A61K35/14 , A61K35/16 , A61L2/00 , A61M1/02 , A61M1/36 , B01J19/12 , A61M1/34 , A01N1/02 , A61L2/08 , C12N7/04
Abstract: Systems and methods treat plasma carrying contaminants and leukocytes that are capable of entraining contaminants. The systems and methods separate leukocytes from the plasma by filtration, thereby removing contaminants entrained within leukocytes. The systems and methods also add to the plasma a photoactive material and emit radiation at a selected wavelength into the plasma to activate the photoactive material and thereby eradicate the contaminant that is free of entrainment by leukocytes.
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Patent Agency Ranking
公开(公告)号：NO314244B1
公开(公告)日：2003-02-24
申请号：NO974874
申请日：1997-10-22
Applicant: BAXTER INT
Inventor： BISCHOF DANIEL F
Abstract: Blood processing systems and methods establish on line communication between a container and a source of blood containing leukocytes and platelets, such as a human donor. The systems and methods create a centrifugal field between the source of blood and the container that separates from the blood an unfinished suspension of platelets having a first physiologic characteristic different than the desired physiologic characteristic. The systems and methods pump the unfinished platelet suspension outside the centrifugal field through a finishing device. The finishing device changes the first physiologic characteristic to the desired physiological characteristic, thereby creating the finished platelet suspension. The systems and methods convey the finished platelet suspension from the finishing device directly into the container. The systems and methods function without interrupting the on line communication between the container and the source of blood.
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公开(公告)号：NO992162A
公开(公告)日：1999-07-06
申请号：NO992162
申请日：1999-05-04
Applicant: PALL CORP , BAXTER INT
Inventor： SUTTER MARK A , BORTON NOEL T , BISCHOF DANIEL F , CHAPMAN JOHN , HERMAN ROBERT E , SUN CHONG-SON
CPC classification number: B01D69/12 , A61M1/3633 , A61M2202/0415 , A61M2202/0439 , B01D61/18 , B01D63/08 , B01D63/081 , A61M2202/0042 , A61M2202/005
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公开(公告)号：CA2074830C
公开(公告)日：1999-03-02
申请号：CA2074830
申请日：1991-12-20
Applicant: BAXTER INT
Inventor： BISCHOF DANIEL F
Abstract: Systems and methods for removing a contaminant from a fluid like blood, regardless of whether the contaminant is carried free within the fluid or entrained within cellular matter carried within the fluid. The systems and methods rely upon photodynamic processes to remove free contaminants from the fluid. The systems and methods rely upon separation processes to remove the cellular matter and, with it, the contaminants it entrains from the fluid. The system (10) includes a treatment device (12) that receives the fluid from a source container (14) and conveys the fluid after treatment to a collection container (16). Treatment device (12) includes housing (18) that encloses an interior chamber (20) which has an inlet (22) for receiving a blood suspension from source container (14) and an outlet (24) for discharging the blood suspension. Device (12) also comprises first element (26) for separating cellular components from the blood, and second element (28) which employs photodynamic therapy to remove the free biological contaminants.
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公开(公告)号：NO974874A
公开(公告)日：1997-10-22
申请号：NO974874
申请日：1997-10-22
Applicant: BAXTER INT
Inventor： BISCHOF DANIEL F
CPC classification number: A61M1/3693 , A61M1/3696 , A61M2202/0427 , A61M2202/0439 , A61M2202/0071 , A61M2202/0057
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公开(公告)号：ES2271965T3
公开(公告)日：2007-04-16
申请号：ES97904262
申请日：1997-02-10
Applicant: BAXTER INT
Inventor： BISCHOF DANIEL F
Abstract: SISTEMAS DE PROCESAMIENTO DE SANGRE Y METODOS PARA ESTABLECER COMUNICACION CONTINUA ENTRE UN RECIPIENTE U UNA FUENTE DE SANGRE QUE CONTIENE LEUCOCITOS Y PLAQUETAS, COMO UN DONANTE HUMANO. LOS SISTEMAS Y LOS METODOS CREAN UN CAMPO CENTRIFUGO (14) ENTRE LA FUENTE DE SANGRE Y EL RECIPIENTE QUE SEPARA A PARTIR DE LA SANGRE UNA SUSPENSION NO TERMINADA DE PLAQUETAS QUE TIENEN UNA PRIMERA CARACTERISTICA FISIOLOGICA DIFERENTE DE LA CARACTERISTICA FISIOLOGICA DESEADA. LOS SISTEMAS Y LOS METODOS BOMBEAN LA SUSPENSION NO TERMINADA DE PLAQUETAS FUERA DEL CAMPO CENTRIFUGO A TRAVES DE UN DISPOSITIVO DE TERMINACION (24). EL DISPOSITIVO DE TERMINACION (24) CAMBIA LA PRIMERA CARACTERISTICA FISIOLOGICA A LA CARACTERISTICA FISIOLOGICA DESEADA, CREANDO LA SUSPENSION DE PLAQUETAS TERMINADA. LOS SISTEMAS Y LOS METODOS TRANSFIEREN DIRECTAMENTE LA SUSPENSION DE PLAQUETAS TERMINADA DESDE EL DISPOSITIVO DE TERMINACION AL RECIPIENTE. LOS SISTEMAS Y LOS METODOS FUNCIONAN SIN INTERRUMPIR LA COMUNICACION CONTINUA ENTREEL RECIPIENTE Y LA FUENTE DE SANGRE.
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