公开(公告)号：DE69322367D1

公开(公告)日：1999-01-14

申请号：DE69322367

申请日：1993-07-14

Applicant: BAXTER INT

Inventor： BACEHOWSKI DAVID ,  CERNY DAVID ,  GLASH DEAN ,  AFFLERBAUGH RICHARD ,  WEST JOSEPH

IPC: A61J1/14 ,  A61J1/00 ,  A61J1/10 ,  A61J1/20 ,  A61J3/00 ,  A61M39/14 ,  B29C65/00 ,  B29C65/04 ,  B29C65/74 ,  B29L22/00 ,  A61M39/00

Abstract: An aseptic/sterile fluid connection between two containers is formed by radio frequency sealing together portions of transfer regions of two containers. Each transfer region has a layer of a relatively high melt temperature material such as a rubber or elastomer positioned between two outer container walls made of a flexible thermoplastic, for example polyvinyl chloride. The transfer regions are placed in registry, and the radio frequency welding fuses together portions of adjacent container outer walls and forms a fluid opening therethrough.

公开(公告)号：DE68917462D1

公开(公告)日：1994-09-15

申请号：DE68917462

申请日：1989-11-06

Applicant: BAXTER INT

Inventor： SMITH SIDNEY ,  GLASH DEAN

IPC: A61J1/00 ,  A61J3/00 ,  A61M1/02 ,  F25C1/22 ,  A61B19/00

公开(公告)号：AU669555B2

公开(公告)日：1996-06-13

申请号：AU4679393

申请日：1993-07-14

Applicant: BAXTER INT

Inventor： BACEHOWSKI DAVID ,  CERNY DAVID ,  GLASH DEAN ,  AFFLERBAUGH RICHARD ,  WEST JOSEPH JR

IPC: A61J1/14 ,  A61J1/00 ,  A61J1/10 ,  A61J1/20 ,  A61J3/00 ,  A61M39/14 ,  B29C65/00 ,  B29C65/04 ,  B29C65/74 ,  B29L22/00 ,  A61M39/00

Abstract: An aseptic/sterile fluid connection between two containers is formed by radio frequency sealing together portions of transfer regions of two containers. Each transfer region has a layer of a relatively high melt temperature material such as a rubber or elastomer positioned between two outer container walls made of a flexible thermoplastic, for example polyvinyl chloride. The transfer regions are placed in registry, and the radio frequency welding fuses together portions of adjacent container outer walls and forms a fluid opening therethrough.

公开(公告)号：DE68917462T2

公开(公告)日：1995-04-20

申请号：DE68917462

申请日：1989-11-06

Applicant: BAXTER INT

Inventor： SMITH SIDNEY ,  GLASH DEAN

IPC: A61J1/00 ,  A61J3/00 ,  A61M1/02 ,  F25C1/22 ,  A61B19/00

公开(公告)号：DE69008664T2

公开(公告)日：1994-12-15

申请号：DE69008664

申请日：1990-01-17

Applicant: BAXTER INT

Inventor： MIRIPOL JEFFREY ,  BILSTAD ARNOLD ,  FOLEY JOHN ,  GLASH DEAN ,  BRATTEN WILLIAM

IPC: A61J3/00 ,  A61K35/14 ,  A61L2/00 ,  A61L2/10 ,  A61M1/36

Abstract: A thin film or layer of white blood cells, such as the contaminating white cells in a platelet concentrate, is irradiated with ultraviolet radiation predominately of a wavelength of 280 to 320 nanometers, and preferably at an intensity of 4 to 20 milliwatts per square cm. to provide a total energy exposure of typically 800 to 20,000 millijoules per square cm. of ultraviolet radiation. The white blood cells so produced substantially lose their capability to set off an immune reaction in an alloimmunized patient. The white blood cells may preferably be placed into such film in a flat, flexible bag made of poly(ethylene-vinyl acetate) plastic, with the flat, flexible bag being stretched in a direction normal to the path of ultraviolet radiation. Novel irradiating devices are also disclosed.

公开(公告)号：DE69008664D1

公开(公告)日：1994-06-09

申请号：DE69008664

申请日：1990-01-17

Applicant: BAXTER INT

Inventor： MIRIPOL JEFFREY ,  BILSTAD ARNOLD ,  FOLEY JOHN ,  GLASH DEAN ,  BRATTEN WILLIAM

IPC: A61J3/00 ,  A61K35/14 ,  A61L2/00 ,  A61L2/10 ,  A61M1/36

Abstract: A thin film or layer of white blood cells, such as the contaminating white cells in a platelet concentrate, is irradiated with ultraviolet radiation predominately of a wavelength of 280 to 320 nanometers, and preferably at an intensity of 4 to 20 milliwatts per square cm. to provide a total energy exposure of typically 800 to 20,000 millijoules per square cm. of ultraviolet radiation. The white blood cells so produced substantially lose their capability to set off an immune reaction in an alloimmunized patient. The white blood cells may preferably be placed into such film in a flat, flexible bag made of poly(ethylene-vinyl acetate) plastic, with the flat, flexible bag being stretched in a direction normal to the path of ultraviolet radiation. Novel irradiating devices are also disclosed.

公开(公告)号：MX9304232A

公开(公告)日：1994-04-29

申请号：MX9304232

申请日：1993-07-13

Applicant: BAXTER INT

Inventor： AFFLERBAUGH RICHARD ,  WEST JOSEPH JR ,  BACEHOWSKI DAVID ,  CERNY DAVID ,  GLASH DEAN

IPC: A61J1/00 ,  A61J1/14 ,  A61J1/10 ,  A61J1/20 ,  A61J3/00 ,  A61M39/14 ,  B29C65/00 ,  B29C65/04 ,  B29C65/74 ,  B29L22/00 ,  A61J1/08

Abstract: An aseptic/sterile fluid connection between two containers is formed by radio frequency sealing together portions of transfer regions of two containers. Each transfer region has a layer of a relatively high melt temperature material such as a rubber or elastomer positioned between two outer container walls made of a flexible thermoplastic, for example polyvinyl chloride. The transfer regions are placed in registry, and the radio frequency welding fuses together portions of adjacent container outer walls and forms a fluid opening therethrough.