公开(公告)号：EP0603388A4

公开(公告)日：1995-06-28

申请号：EP93917202

申请日：1993-07-14

Applicant: BAXTER INT

Inventor： BACEHOWSKI DAVID ,  CERNY DAVID ,  GLASH DEAN ,  AFFLERBAUGH RICHARD ,  WEST JOSEPH JR

IPC: A61J1/14 ,  A61J1/00 ,  A61J1/10 ,  A61J1/20 ,  A61J3/00 ,  A61M39/14 ,  B29C65/00 ,  B29C65/04 ,  B29C65/74 ,  B29L22/00

CPC classification number: A61J1/2089 ,  A61J1/10 ,  A61J1/2027 ,  A61M39/143 ,  B29C65/04 ,  B29C65/743 ,  B29C66/1122 ,  B29C66/43 ,  B29C66/4312 ,  B29C66/71 ,  B29C66/723 ,  B29C66/73115 ,  B29C66/73143 ,  B29C66/81422 ,  B29C66/81427 ,  B29C66/8221 ,  B29C66/8322 ,  B29C66/83221 ,  B29C66/857 ,  B29C66/8614 ,  B29C2793/0045 ,  B29L2023/007 ,  B29L2031/7148 ,  B29K2027/06

Abstract: An aseptic/sterile fluid connection between two containers formed by radio frequency sealing together portions of transfer regions (14B, 16B) of two containers, each transfer region having a layer of a relatively high melt temperature material such as a rubber or elastomer (18, 20) positioned between two outer container walls made of a flexible thermoplastic, for example polyvinyl chloride. The transfer regions are placed in registry and the radio frequency welding fuses together portions of adjacent container outer walls and forms a fluid opening therethrough.

公开(公告)号：CA2116433C

公开(公告)日：2004-12-28

申请号：CA2116433

申请日：1993-07-14

Applicant: BAXTER INT

Inventor： BACEHOWSKI DAVID ,  CERNY DAVID ,  GLASH DEAN ,  AFFLERBAUGH RICHARD ,  WEST JOSEPH JR

IPC: A61J1/14 ,  A61J1/00 ,  A61J1/10 ,  A61J1/20 ,  A61J3/00 ,  A61M39/14 ,  B29C65/00 ,  B29C65/04 ,  B29C65/74 ,  B29L22/00

Abstract: An aseptic/sterile fluid connection between two containers formed by radio frequency sealing together portions of transfer regions (14B, 16B) of two containers; each transfer region having a layer of a relatively high melt temperature material such as a rubber or elastomer (18; 20) positioned between two outer container walls ma de of a flexible thermoplastic, for example polyvinyl chloride. The transfer regions are placed in registry and the radio frequenc y welding fuses together portions of adjacent container outer walls and forms a fluid opening therethrough.

公开(公告)号：CA2031522C

公开(公告)日：1998-08-25

申请号：CA2031522

申请日：1990-01-17

Applicant: BAXTER INT

Inventor： MIRIPOL JEFFREY E ,  BILSTAD ARNOLD ,  FOLEY JOHN ,  GLASH DEAN ,  BRATTEN WILLIAM R

IPC: A61J3/00 ,  A61K35/14 ,  A61L2/00 ,  A61L2/10 ,  A61M1/36 ,  A61N5/06

Abstract: A thin film (10) or layer (10) of white blood cells, such as the contaminating w hite cells in a platelet concentrate, is irradiated with ultraviolet radiation predominantely of a wavelength of 280 to 320 nanomet ers, and preferably at an intensity of 4 to 20 milliwatts per square cm. to provide a total energy exposure of typically 800 to 20,000 millijoules per square cm. of ultraviolet radiation. The white blood cells so processed substantially lose their capabilit y to set off an immune reaction in an alloimmunized patient. The white blood cells may preferably be placed into such film in a flat (10), flexible bag (10) made of poly(ethylene-vinyl acetate) plastic, with the flat (10), flexible bag (10) being stretched in a dir ection normal to the path of ultraviolet radiation. Novel irradiating devices (40) are also disclosed.

公开(公告)号：AU4679393A

公开(公告)日：1994-01-31

申请号：AU4679393

申请日：1993-07-14

Applicant: BAXTER INT

Inventor： BACEHOWSKI DAVID ,  CERNY DAVID ,  GLASH DEAN ,  AFFLERBAUGH RICHARD ,  WEST JOSEPH JR

IPC: A61J1/14 ,  A61J1/00 ,  A61J1/10 ,  A61J1/20 ,  A61J3/00 ,  A61M39/14 ,  B29C65/00 ,  B29C65/04 ,  B29C65/74 ,  B29L22/00 ,  A61M39/00

Abstract: An aseptic/sterile fluid connection between two containers is formed by radio frequency sealing together portions of transfer regions of two containers. Each transfer region has a layer of a relatively high melt temperature material such as a rubber or elastomer positioned between two outer container walls made of a flexible thermoplastic, for example polyvinyl chloride. The transfer regions are placed in registry, and the radio frequency welding fuses together portions of adjacent container outer walls and forms a fluid opening therethrough.

公开(公告)号：CA2031522A1

公开(公告)日：1990-11-03

申请号：CA2031522

申请日：1990-01-17

Applicant: BAXTER INT

Inventor： MIRIPOL JEFFREY E ,  BILSTAD ARNOLD ,  FOLEY JOHN ,  GLASH DEAN ,  BRATTEN WILLIAM R

IPC: A61J3/00 ,  A61K35/14 ,  A61L2/00 ,  A61L2/10 ,  A61M1/36

Abstract: A thin film or layer of white blood cells, such as the contaminating white cells in a platelet concentrate, is irradiated with ultraviolet radiation predominately of a wavelength of 280 to 320 nanometers, and preferably at an intensity of 4 to 20 milliwatts per square cm. to provide a total energy exposure of typically 800 to 20,000 millijoules per square cm. of ultraviolet radiation. The white blood cells so produced substantially lose their capability to set off an immune reaction in an alloimmunized patient. The white blood cells may preferably be placed into such film in a flat, flexible bag made of poly(ethylene-vinyl acetate) plastic, with the flat, flexible bag being stretched in a direction normal to the path of ultraviolet radiation. Novel irradiating devices are also disclosed.

公开(公告)号：DK0603388T3

公开(公告)日：1999-08-16

申请号：DK93917202

申请日：1993-07-14

Applicant: BAXTER INT

Inventor： BACEHOWSKI DAVID ,  CERNY DAVID ,  GLASH DEAN ,  AFFLERBAUGH RICHARD ,  WEST JOSEPH JR

IPC: A61J1/14 ,  A61J1/00 ,  A61J1/10 ,  A61J1/20 ,  A61J3/00 ,  A61M39/14 ,  B29C65/00 ,  B29C65/04 ,  B29C65/74 ,  B29L22/00 ,  A61M39/00

Abstract: An aseptic/sterile fluid connection between two containers is formed by radio frequency sealing together portions of transfer regions of two containers. Each transfer region has a layer of a relatively high melt temperature material such as a rubber or elastomer positioned between two outer container walls made of a flexible thermoplastic, for example polyvinyl chloride. The transfer regions are placed in registry, and the radio frequency welding fuses together portions of adjacent container outer walls and forms a fluid opening therethrough.

公开(公告)号：AT173914T

公开(公告)日：1998-12-15

申请号：AT93917202

申请日：1993-07-14

Applicant: BAXTER INT

Inventor： BACEHOWSKI DAVID ,  CERNY DAVID ,  GLASH DEAN ,  AFFLERBAUGH RICHARD ,  WEST JOSEPH JR

IPC: A61J1/14 ,  A61J1/00 ,  A61J1/10 ,  A61J1/20 ,  A61J3/00 ,  A61M39/14 ,  B29C65/00 ,  B29C65/04 ,  B29C65/74 ,  B29L22/00 ,  A61M39/00

Abstract: An aseptic/sterile fluid connection between two containers is formed by radio frequency sealing together portions of transfer regions of two containers. Each transfer region has a layer of a relatively high melt temperature material such as a rubber or elastomer positioned between two outer container walls made of a flexible thermoplastic, for example polyvinyl chloride. The transfer regions are placed in registry, and the radio frequency welding fuses together portions of adjacent container outer walls and forms a fluid opening therethrough.

公开(公告)号：CA2116433A1

公开(公告)日：1994-01-20

申请号：CA2116433

申请日：1993-07-14

Applicant: BAXTER INT

Inventor： BACEHOWSKI DAVID ,  CERNY DAVID ,  GLASH DEAN ,  AFFLERBAUGH RICHARD ,  WEST JOSEPH JR

IPC: A61J1/14 ,  A61J1/00 ,  A61J1/10 ,  A61J1/20 ,  A61J3/00 ,  A61M39/14 ,  B29C65/00 ,  B29C65/04 ,  B29C65/74 ,  B29L22/00

Abstract: 2116433 9401072 PCTABS00030 An aseptic/sterile fluid connection between two containers formed by radio frequency sealing together portions of transfer regions (14B, 16B) of two containers, each transfer region having a layer of a relatively high melt temperature material such as a rubber or elastomer (18, 20) positioned between two outer container walls made of a flexible thermoplastic, for example polyvinyl chloride. The transfer regions are placed in registry and the radio frequency welding fuses together portions of adjacent container outer walls and forms a fluid opening therethrough.

公开(公告)号：DE69322367T2

公开(公告)日：1999-08-26

申请号：DE69322367

申请日：1993-07-14

Applicant: BAXTER INT

Inventor： BACEHOWSKI DAVID ,  CERNY DAVID ,  GLASH DEAN ,  AFFLERBAUGH RICHARD ,  WEST JOSEPH

IPC: A61J1/14 ,  A61J1/00 ,  A61J1/10 ,  A61J1/20 ,  A61J3/00 ,  A61M39/14 ,  B29C65/00 ,  B29C65/04 ,  B29C65/74 ,  B29L22/00 ,  A61M39/00

Abstract: An aseptic/sterile fluid connection between two containers is formed by radio frequency sealing together portions of transfer regions of two containers. Each transfer region has a layer of a relatively high melt temperature material such as a rubber or elastomer positioned between two outer container walls made of a flexible thermoplastic, for example polyvinyl chloride. The transfer regions are placed in registry, and the radio frequency welding fuses together portions of adjacent container outer walls and forms a fluid opening therethrough.

公开(公告)号：ES2127290T3

公开(公告)日：1999-04-16

申请号：ES93917202

申请日：1993-07-14

Applicant: BAXTER INT

Inventor： BACEHOWSKI DAVID ,  CERNY DAVID ,  GLASH DEAN ,  AFFLERBAUGH RICHARD ,  WEST JOSEPH JR

IPC: A61J1/00 ,  A61J1/10 ,  A61J1/14 ,  A61J1/20 ,  A61J3/00 ,  A61M39/14 ,  B29C65/00 ,  B29C65/04 ,  B29C65/74 ,  B29L22/00 ,  A61M39/00

Abstract: An aseptic/sterile fluid connection between two containers is formed by radio frequency sealing together portions of transfer regions of two containers. Each transfer region has a layer of a relatively high melt temperature material such as a rubber or elastomer positioned between two outer container walls made of a flexible thermoplastic, for example polyvinyl chloride. The transfer regions are placed in registry, and the radio frequency welding fuses together portions of adjacent container outer walls and forms a fluid opening therethrough.