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公开(公告)号：WO1995017236A1
公开(公告)日：1995-06-29
申请号：PCT/US1994014819
申请日：1994-12-20
Applicant: BAXTER INTERNATIONAL INC.
Inventor： BAXTER INTERNATIONAL INC. , STERNBERG, Shmuel , LYNN, Daniel, R.
IPC: B01D25/00
CPC classification number: B01D39/2017 , A61M1/0222 , A61M1/3636 , A61M1/3652 , A61M2202/0439 , B01D29/012 , B01D29/58 , B01D29/908 , B01D39/083 , B01D39/1623 , B01D39/18 , B01D2239/0471 , B01D2239/0618 , B01D2239/065 , B01D2239/0654 , B01D2239/1233 , Y10S264/26 , Y10S264/48 , A61M2202/0057
Abstract: The filter device (16) for removing leukocytes is disclosed. The outer housing (18) enclosing the filter pad assembly (20) includes two sheets (44, 46) of flexible plastic material. The filter device (16) includes tangential side ports (36, 38) as an inlet and an outlet. The filter pad assembly (20) includes a composite of three media regions (28, 30, 32) including non-contiguous layers (40) having an overall thickness of greater than about 6 mm but not more than about 10 mm. Each non-contiguous layer (40) comprises an interlocked matrix of polyester fibers, fiberglass fibers, and cellulose acetate fibrets. The matrix has a number average fiber diameter no greater than about 0.23 micron.
Abstract translation: 公开了用于除去白细胞的过滤装置（16）。 包围过滤垫组件（20）的外壳（18）包括两个柔性塑料材料片（44,46）。 过滤装置（16）包括作为入口和出口的切向侧端口（36,38）。 过滤垫组件（20）包括三个介质区域（28,30,32）的复合材料，其包括总厚度大于约6mm但不大于约10mm的不连续层（40）。 每个非邻接层（40）包括聚酯纤维，玻璃纤维纤维和乙酸纤维素纤维的互锁基质。 基质的数均纤维直径不大于约0.23微米。
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公开(公告)号：EP0877648B1
公开(公告)日：2006-11-22
申请号：EP97944406.4
申请日：1997-09-22
Applicant: Baxter International Inc.
Inventor： PRINCE, Paul, R. , PEKKARINEN, Michael, O. , BELLAMY, David, Jr. , STERNBERG, Shmuel
IPC: B01D65/02
CPC classification number: B01D65/08 , A61M1/262 , A61M1/265 , A61M1/34 , A61M1/3403 , A61M1/341 , A61M2202/0429 , A61M2202/0439 , A61M2205/3334 , B01D39/1692 , B01D61/147 , B01D61/22 , B01D63/16 , B01D69/02 , B01D2321/20 , B01D2321/2025 , B01D2321/2058 , B01D2321/2066 , A61M2202/0042 , A61M2202/0035
Abstract: A method and apparatus for filtering suspensions of medical and biological fluids, one aspect of which is separating a suspension comprising at least two types of particles (104) and (108) which are differently sized or shaped and in which a first type of red cell particle (104) may be deformable at a relatively lower force and/or faster rate than a second type of white cell particle (108). A filter membrane (100) is provided having pores (102) with substantially precisely dimensioned pore sizes, with the pores (102) being dimensioned to allow passage of the first type of particle (104) without distortion or only minimal distortion and passage of the second type of particle (108) only with substantial distortion. Because the filter membrane (100) has precisely dimensioned pores (102), with spacing between the pores (102) being maintained despite the smaller interval between the pores (102), the porosity of the membrane (100) may be relatively much greater, allowing faster filtration rates while reducing shear exposure time and consequently reducing particle damage. Various methods for preventing clogging of the membrane (100) are also disclosed.
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公开(公告)号：EP2367584B1
公开(公告)日：2015-04-22
申请号：EP09792320.5
申请日：2009-09-08
Applicant: Baxter International Inc. , Baxter Healthcare SA
Inventor： STERNBERG, Shmuel , DESAI, Siddharth, B. , BLACK, Larry , PAULEY, Robin, G.
CPC classification number: G01D7/005 , A61M5/141 , A61M5/3146 , A61M5/385 , A61M39/10 , A61M39/20 , A61M2005/1402 , A61M2005/3125 , A61M2039/205 , A61M2205/331 , A61M2205/7536
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公开(公告)号：EP0684864B1
公开(公告)日：2004-03-10
申请号：EP95906087.2
申请日：1994-12-20
Applicant: BAXTER INTERNATIONAL INC.
Inventor： STERNBERG, Shmuel
CPC classification number: G01N15/08 , B29C65/04 , B29C65/08 , B29C66/1122 , B29C66/1312 , B29C66/24221 , B29C66/53261 , B29C66/53262 , B29C66/54 , B29C66/71 , B29C66/73921 , B29C66/81423 , B29C66/81431 , B29C66/8322 , B29C66/83221 , B29C66/9513 , B29K2027/06
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15.发明公开
公开(公告)号：EP1140334A1
公开(公告)日：2001-10-10
申请号：EP00941430.1
申请日：2000-06-15
Applicant: BAXTER INTERNATIONAL INC.
Inventor： STERNBERG, Shmuel , BOGGS, Daniel, R. , PAULEY, Robin, G. , MOY, Bonny
IPC: B01D71/28
CPC classification number: B01D67/0088 , B01D63/16 , B01D69/02 , B01D71/34
Abstract: Microporous membranes (10) comprising polyvinylidene difluoride and methods for making such membranes are disclosed. The membranes (10), which are not crosslinked and are not contacted with a strong alkali solution during manufacture, are wettable by aqueous solution even after repeated wetting and drying. The membrane includes a support (18) and surfaces (11) treated with a hydrophilic coating. Separately, such membranes are also useful in apparatus (60) for separating a biological fluid into two or more components.
Abstract translation: 公开了包含聚偏二氟乙烯的微孔膜（10）和用于制造这种膜的方法。 没有交联并且在制造过程中不与强碱溶液接触的膜（10）即使在反复润湿和干燥之后也可以通过水溶液润湿。 该膜包括支持物（18）和用亲水涂层处理过的表面（11）。 单独地，这种膜也可用于将生物流体分离成两种或更多种组分的设备（60）。
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Patent Agency Ranking
公开(公告)号：EP2231313B1
公开(公告)日：2016-01-27
申请号：EP08854177.6
申请日：2008-10-06
Applicant: Baxter International Inc. , Baxter Healthcare SA
Inventor： STERNBERG, Shmuel
CPC classification number: B01D69/02 , A61M1/16 , B01D67/0083 , B01D67/0088 , B01D69/06 , B01D69/08 , B01D2323/08 , B01D2323/283 , B01D2325/02 , Y10T428/1376 , Y10T428/24802 , Y10T428/24942
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公开(公告)号：EP1226397A2
公开(公告)日：2002-07-31
申请号：EP00976832.6
申请日：2000-11-02
Applicant: Baxter International Inc.
Inventor： STERNBERG, Shmuel
CPC classification number: D01F1/10 , C09K5/063 , D01D5/247 , F28D20/023 , Y02E60/145
Abstract: A vessel (1) for preparing a polymer solution contains coils (7) and is positioned within a chamber (3).
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公开(公告)号：EP1094876A1
公开(公告)日：2001-05-02
申请号：EP99931933.8
申请日：1999-06-25
Applicant: BAXTER INTERNATIONAL INC.
Inventor： BOGGS, Daniel, R. , STERNBERG, Shmuel , PAULEY, Robin, G. , MCLARTY, Donna, L.
CPC classification number: B01J20/28033 , A61M1/3686 , B01D69/141 , B01J20/28004 , B01J20/28026 , B01J20/28035
Abstract: Membranes and methods for making membranes are disclosed. The membranes (10) include a polymeric matrix (16) and a particulate material immobilized within the matrix. The membrane may further include a skin layer (19) having randomly spaced surface pores (21). The membranes may find particular application in methods and apparatus for removing organic compounds from a biological fluid as part of a pathogen inactivation treatment.
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公开(公告)号：EP0784457A1
公开(公告)日：1997-07-23
申请号：EP95938214.0
申请日：1995-10-04
Applicant: BAXTER INTERNATIONAL INC.
Inventor： BRAUKER, James, H. , MARTINSON, Laura, A. , STERNBERG, Shmuel , BELLAMY, David
CPC classification number: B01D69/02 , A61F2/00 , A61F2/0077 , A61F2/062 , A61F2/30767 , A61F2002/30911 , A61L27/18 , A61L27/50 , B01D67/003 , B01D67/0034 , B01D69/12 , B01D71/64 , B01D2325/08 , B01D2325/24 , C08L79/08
Abstract: Polymer membrane structures are microfabricated from polyimide film by lithography or etching. The microfabricated structures have systematically varied dimensions and geometries conducive to implanting in host tissue and the promotion, when implanted, of new vascular structures.
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公开(公告)号：EP1487559A1
公开(公告)日：2004-12-22
申请号：EP03711447.7
申请日：2003-03-06
Applicant: BAXTER INTERNATIONAL INC.
Inventor： STERNBERG, Shmuel , PAULEY, Robin, G.
CPC classification number: B01J20/28026 , A61J1/10 , A61J1/1468 , A61J1/1487 , A61M1/0218 , A61M1/3679 , A61M1/3683 , A61M1/3686 , B01D15/00 , B01J20/26 , B01J20/261 , B01J20/28033 , B01J20/2805 , B01J20/321 , B01J20/3223 , B01J20/324 , B01J20/327 , B01J20/3276 , B01J20/3282
Abstract: Devices for removing compounds from a biological fluid are disclosed. The devices (20) include sorbent beads (22) applied to an adhesive-surface (26, 28) of support (24). The devices (20) may be used in 'batch-type' or 'flow-through' systems.
Abstract translation: 公开了从生物流体中除去化合物的装置。 装置（20）包括施加到支撑件（24）的粘合剂表面（26,28）上的吸附剂珠（22）。 装置（20）可以用于“分批式”或“流通”系统。
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