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    12.
    发明专利
    未知

    公开(公告)号：SE430205B

    公开(公告)日：1983-10-31

    申请号：SE7703752

    申请日：1977-03-31

    Applicant: CIBA GEIGY AG

    Inventor： KUHNE M ,  KOCHER C ,  GALLAY J J

    IPC: A23K1/16 ,  A61K31/535 ,  A61P3/00 ,  C07D213/81

    Abstract: Feed additives for promoting the growth of domestic and productive animals, which additives contain as active ingredient at least one compound of the formula I (I) wherein R1 represents a 5- or 6-membered, N-, S- or O-containing heterocyclic-aromatic radical, optionally substituted by halogen, lower alkyl, phenyl, nitro, cyano, (R3)2NCO-, (R3)2N-, R3O-, R3SO2-, R3SO- or R3S-, R2 represents lower alkyl, alkenyl or cycloalkyl optionally bound by way of an alkylene bridge, and R3 represents lower alkyl, alkenyl or alkoxyalkyl having a total of up to 8 carbon atoms, OR QUATERNARY AMMONIUM COMPOUNDS OR N-oxides of the N-containing heterocyclic-aromatic radicals, together with suitable carriers and/or distributing agents.

    BENZIMIDAZOLE DERIVATIVES AND ANTHELMINTIC COMPOSITIONS
    13.
    发明专利
    BENZIMIDAZOLE DERIVATIVES AND ANTHELMINTIC COMPOSITIONS 未知

    公开(公告)号：NZ186936A

    公开(公告)日：1980-10-24

    申请号：NZ18693678

    申请日：1978-04-11

    Applicant: CIBA GEIGY AG

    Inventor： GALLAY J J ,  RECHSTEINER O ,  MEYER A ,  SCHELLENBAUM M ,  KUHNE M

    IPC: A61K31/415 ,  A61K31/4184 ,  A61P33/00 ,  A61P33/10 ,  C07D235/28

    Abstract: Benzimidazole derivatives of the formula in which R is an alkyl group having 1 to 6 carbon atoms, an alkenyl group having 3 to 5 carbon atoms, an alkynyl group having 3 to 5 carbon atoms or a benzyl group, which is unsubstituted or monosubstituted to disubstituted by a methyl group, halogen or a nitro group; R1 is hydrogen, an alkanoyl group having 1 to 4 carbon atoms, an alkoxycarbonyl group having 1 to 4 carbon atoms, a N,N-dialkylcarbamoyl group or N,N-dialkylthiocarbamoyl group, each having 1 to 4 carbon atoms in the alkyl groups, an alkylsulphonyl group having 1 to 4 carbon atoms, a benzoyl group, a phenylsulphonyl group, a 4-methylphenylsulphonyl group or the radical, in which Q is a carbonyl group, a thiocarbonyl group or an oxalyl group; R2 is hydrogen, halogen or a methyl group; R3 is hydrogen, halogen, a methyl group or an alkoxy group having 1 to 4 carbon atoms; R4 is hydrogen, halogen or a methyl group; X is oxygen or sulphur; Y is halogen, an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms, a methylthio group, a methylsulphinyl group, a methylsulphonyl group, a trifluoromethyl group, a nitro group, a hydroxyl group, a cyano group or an alkanoyl group having 1 to 4 carbon atoms in the alkyl moiety m is 0, 1, 2 or 3; and n is 0, 1 or 2. Included are, if R1 is not hydrogen, the tautomeric compounds of the formula I. The compounds are effective for combating helminths in domestic and useful animals.

    BENZIMIDAZOLE DERIVATIVES AND ANTHELMINTIC COMPOSITIONS
    14.
    发明专利
    BENZIMIDAZOLE DERIVATIVES AND ANTHELMINTIC COMPOSITIONS 未知

    公开(公告)号：NZ186933A

    公开(公告)日：1980-10-24

    申请号：NZ18693378

    申请日：1978-04-11

    Applicant: CIBA GEIGY AG

    Inventor： RECHSTEINER O ,  GALLAY J J ,  MEYER A ,  AUFDERHAAR E ,  SCHELLENBAUM M ,  KUHNE M ,  FURNEAUX J-P

    IPC: A01N43/52 ,  A61K31/415 ,  A61K31/4184 ,  A61P33/00 ,  C07D235/28

    Abstract: Benzimidazole derivatives of the formula in which R and R1 independently of one another are each hydrogen, an alkanoyl group having 1 to 4 carbon atoms, an alkoxycarbonyl group having 1 to 4 carbon atoms, an alkylsulphonyl group having 1 to 4 carbon atoms, a benzoyl group, a phenylsulphonyl group or a p-methylphenylsulphonyl group; R2 and R4 independently of one another are each hydrogen, halogen or a methyl group, R3 is hydrogen, halogen, a methyl group or a methoxy group; X is oxygen or sulphur; Y is halogen, an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms, a methylthio group, a methylsulphinyl group, a methylsulphonyl group, a trifluoromethyl group, a nitro group, a hydroxyl group, a cyano group or an acetyl group; and m is 0, 1, 2 or 3; and if one of the two radicals R or R1 is hydrogen, the position of the other of these radicals on the N atoms cannot be clearly established, including, when at least one of the two radicals R or R1 is hydrogen, the possible tautomeric compounds of the formula I; and the disulphides obtainable by oxidation of compounds of the formula I. The compounds are useful for combating helminths in domestic animals and productive animals.

    15.
    发明专利
    未知

    公开(公告)号：SE7804058L

    公开(公告)日：1978-10-13

    申请号：SE7804058

    申请日：1978-04-11

    Applicant: CIBA GEIGY AG

    Inventor： AUFDERHAAR E ,  GALLAY J J ,  KUHNE M ,  MEYER A ,  RECHSTEINER O ,  SCHELLENBAUM M ,  FUMEAUX J-P

    IPC: A01N43/52 ,  A61K31/415 ,  A61K31/4184 ,  A61P33/00 ,  C07D235/28

    Abstract: Benzimidazole derivatives of the formula in which R and R1 independently of one another are each hydrogen, an alkanoyl group having 1 to 4 carbon atoms, an alkoxycarbonyl group having 1 to 4 carbon atoms, an alkylsulphonyl group having 1 to 4 carbon atoms, a benzoyl group, a phenylsulphonyl group or a p-methylphenylsulphonyl group; R2 and R4 independently of one another are each hydrogen, halogen or a methyl group, R3 is hydrogen, halogen, a methyl group or a methoxy group; X is oxygen or sulphur; Y is halogen, an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms, a methylthio group, a methylsulphinyl group, a methylsulphonyl group, a trifluoromethyl group, a nitro group, a hydroxyl group, a cyano group or an acetyl group; and m is 0, 1, 2 or 3; and if one of the two radicals R or R1 is hydrogen, the position of the other of these radicals on the N atoms cannot be clearly established, including, when at least one of the two radicals R or R1 is hydrogen, the possible tautomeric compounds of the formula I; and the disulphides obtainable by oxidation of compounds of the formula I. The compounds are useful for combating helminths in domestic animals and productive animals.

    17.
    发明专利
    未知

    公开(公告)号：SE7703752L

    公开(公告)日：1977-10-02

    申请号：SE7703752

    申请日：1977-03-31

    Applicant: CIBA GEIGY AG

    Inventor： KUHNE M ,  KOCHER C ,  GALLAY J J

    IPC: A23K1/16 ,  A61K31/535 ,  A61P3/00 ,  C07D213/81

    Abstract: Feed additives for promoting the growth of domestic and productive animals, which additives contain as active ingredient at least one compound of the formula I (I) wherein R1 represents a 5- or 6-membered, N-, S- or O-containing heterocyclic-aromatic radical, optionally substituted by halogen, lower alkyl, phenyl, nitro, cyano, (R3)2NCO-, (R3)2N-, R3O-, R3SO2-, R3SO- or R3S-, R2 represents lower alkyl, alkenyl or cycloalkyl optionally bound by way of an alkylene bridge, and R3 represents lower alkyl, alkenyl or alkoxyalkyl having a total of up to 8 carbon atoms, OR QUATERNARY AMMONIUM COMPOUNDS OR N-oxides of the N-containing heterocyclic-aromatic radicals, together with suitable carriers and/or distributing agents.

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