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    ANTHELMINTICA
    3.
    发明专利
    ANTHELMINTICA 未知

    公开(公告)号：ZA782086B

    公开(公告)日：1979-03-28

    申请号：ZA782086

    申请日：1978-04-11

    Applicant: CIBA GEIGY AG

    Inventor： GALLAY J ,  KUEHNE M ,  RECHSTEINER O ,  MEYER A ,  SCHELLENBAUM M

    IPC: A61K31/415 ,  A61K31/4184 ,  A61P33/00 ,  A61P33/10 ,  C07D235/28 ,  C07D233/54

    Abstract: Benzimidazole derivatives of the formula in which R is an alkyl group having 1 to 6 carbon atoms, an alkenyl group having 3 to 5 carbon atoms, an alkynyl group having 3 to 5 carbon atoms or a benzyl group, which is unsubstituted or monosubstituted to disubstituted by a methyl group, halogen or a nitro group; R1 is hydrogen, an alkanoyl group having 1 to 4 carbon atoms, an alkoxycarbonyl group having 1 to 4 carbon atoms, a N,N-dialkylcarbamoyl group or N,N-dialkylthiocarbamoyl group, each having 1 to 4 carbon atoms in the alkyl groups, an alkylsulphonyl group having 1 to 4 carbon atoms, a benzoyl group, a phenylsulphonyl group, a 4-methylphenylsulphonyl group or the radical, in which Q is a carbonyl group, a thiocarbonyl group or an oxalyl group; R2 is hydrogen, halogen or a methyl group; R3 is hydrogen, halogen, a methyl group or an alkoxy group having 1 to 4 carbon atoms; R4 is hydrogen, halogen or a methyl group; X is oxygen or sulphur; Y is halogen, an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms, a methylthio group, a methylsulphinyl group, a methylsulphonyl group, a trifluoromethyl group, a nitro group, a hydroxyl group, a cyano group or an alkanoyl group having 1 to 4 carbon atoms in the alkyl moiety m is 0, 1, 2 or 3; and n is 0, 1 or 2. Included are, if R1 is not hydrogen, the tautomeric compounds of the formula I. The compounds are effective for combating helminths in domestic and useful animals.

    7.
    发明专利
    未知

    公开(公告)号：SE339357B

    公开(公告)日：1971-10-04

    申请号：SE1637767

    申请日：1967-11-29

    Applicant: CIBA GEIGY AG

    Inventor： SCHELLENBAUM M ,  DUENNENBERGER M

    IPC: C07D263/56 ,  C07D263/57 ,  C07D263/60 ,  D06M16/00 ,  A01N9/22 ,  A01N9/28

    Abstract: 1,185,238. Compositions comprising oxazole derivatives. CIBA Ltd. 29 Nov., 1967 [30 Nov., 1966], No. 54406/67. Heading A5E. [Also in Divisions C2 and C5] Disinfectant compositions comprise as active ingredient at least one 2-(2'-hydroxyphenyl oxazole of the general formula or an alkali metal salt thereof, wherein R is an aromatic ring system containing at most 2 six-membered rings and X represents a benzene residue which is substituted by a hydroxyl group in the ortho-position to the bond with the oxazole ring, together with a carrier or diluent, and if the carrier or diluent is a solvent, a surface active agent. A large number of industrial uses are specified, including an example relating to impregnating a woollen fabric with the composition.

    9.
    发明专利
    未知

    公开(公告)号：DK159478A

    公开(公告)日：1978-10-13

    申请号：DK159478

    申请日：1978-04-11

    Applicant: CIBA GEIGY AG

    Inventor： GALLAY J J ,  KUEHNE M ,  MEYER A ,  RECHSTEINER O ,  SCHELLENBAUM M

    IPC: A61K31/415 ,  A61K31/4184 ,  A61P33/00 ,  A61P33/10 ,  C07D235/28 ,  C07D

    Abstract: Benzimidazole derivatives of the formula in which R is an alkyl group having 1 to 6 carbon atoms, an alkenyl group having 3 to 5 carbon atoms, an alkynyl group having 3 to 5 carbon atoms or a benzyl group, which is unsubstituted or monosubstituted to disubstituted by a methyl group, halogen or a nitro group; R1 is hydrogen, an alkanoyl group having 1 to 4 carbon atoms, an alkoxycarbonyl group having 1 to 4 carbon atoms, a N,N-dialkylcarbamoyl group or N,N-dialkylthiocarbamoyl group, each having 1 to 4 carbon atoms in the alkyl groups, an alkylsulphonyl group having 1 to 4 carbon atoms, a benzoyl group, a phenylsulphonyl group, a 4-methylphenylsulphonyl group or the radical, in which Q is a carbonyl group, a thiocarbonyl group or an oxalyl group; R2 is hydrogen, halogen or a methyl group; R3 is hydrogen, halogen, a methyl group or an alkoxy group having 1 to 4 carbon atoms; R4 is hydrogen, halogen or a methyl group; X is oxygen or sulphur; Y is halogen, an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms, a methylthio group, a methylsulphinyl group, a methylsulphonyl group, a trifluoromethyl group, a nitro group, a hydroxyl group, a cyano group or an alkanoyl group having 1 to 4 carbon atoms in the alkyl moiety m is 0, 1, 2 or 3; and n is 0, 1 or 2. Included are, if R1 is not hydrogen, the tautomeric compounds of the formula I. The compounds are effective for combating helminths in domestic and useful animals.

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