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    ANTHELMINTIC COMPOSITIONS CONTAINING AN ANILINOMETHYLENEMALONONITRILE DERIVATIVE
    1.
    发明专利
    ANTHELMINTIC COMPOSITIONS CONTAINING AN ANILINOMETHYLENEMALONONITRILE DERIVATIVE 未知

    公开(公告)号：NZ186178A

    公开(公告)日：1980-08-26

    申请号：NZ18617878

    申请日：1978-01-09

    Applicant: CIBA GEIGY AG

    Inventor： DRABEK J ,  MEYER A

    IPC: A61K20060101 ,  A61K31/275 ,  C07C255/30 ,  C07C255/58

    Abstract: This invention concerns anthelmintic compositions which contain as active component anilinomethylenemalononitrile derivatives corresponding to the formula wherein R1 represents hydrogen, C1-C6alkyl, the propargyl group or the benzyl radical, R2 represents hydrogen, C1-C4alkyl, halogen, the trifluoromethyl group, the nitro group or the cyano group, R3 represents hydrogen, halogen, the trifluoromethyl group or the nitro group, and R4 represents hydrogen or halogen, WITH THE PROVISO THAT R1 may only be the propargyl group or the benzyl radical if at least one of the symbols R2 or R3 represents the trifluoromethyl group, and the use of the compositions for combating helminths in domestic animals and productive livestock.

    ANTHELMINTICA
    2.
    发明专利
    ANTHELMINTICA 未知

    公开(公告)号：ZA782086B

    公开(公告)日：1979-03-28

    申请号：ZA782086

    申请日：1978-04-11

    Applicant: CIBA GEIGY AG

    Inventor： GALLAY J ,  KUEHNE M ,  RECHSTEINER O ,  MEYER A ,  SCHELLENBAUM M

    IPC: A61K31/415 ,  A61K31/4184 ,  A61P33/00 ,  A61P33/10 ,  C07D235/28 ,  C07D233/54

    Abstract: Benzimidazole derivatives of the formula in which R is an alkyl group having 1 to 6 carbon atoms, an alkenyl group having 3 to 5 carbon atoms, an alkynyl group having 3 to 5 carbon atoms or a benzyl group, which is unsubstituted or monosubstituted to disubstituted by a methyl group, halogen or a nitro group; R1 is hydrogen, an alkanoyl group having 1 to 4 carbon atoms, an alkoxycarbonyl group having 1 to 4 carbon atoms, a N,N-dialkylcarbamoyl group or N,N-dialkylthiocarbamoyl group, each having 1 to 4 carbon atoms in the alkyl groups, an alkylsulphonyl group having 1 to 4 carbon atoms, a benzoyl group, a phenylsulphonyl group, a 4-methylphenylsulphonyl group or the radical, in which Q is a carbonyl group, a thiocarbonyl group or an oxalyl group; R2 is hydrogen, halogen or a methyl group; R3 is hydrogen, halogen, a methyl group or an alkoxy group having 1 to 4 carbon atoms; R4 is hydrogen, halogen or a methyl group; X is oxygen or sulphur; Y is halogen, an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms, a methylthio group, a methylsulphinyl group, a methylsulphonyl group, a trifluoromethyl group, a nitro group, a hydroxyl group, a cyano group or an alkanoyl group having 1 to 4 carbon atoms in the alkyl moiety m is 0, 1, 2 or 3; and n is 0, 1 or 2. Included are, if R1 is not hydrogen, the tautomeric compounds of the formula I. The compounds are effective for combating helminths in domestic and useful animals.

    5.
    发明专利
    未知

    公开(公告)号：DK9178A

    公开(公告)日：1978-07-11

    申请号：DK9178

    申请日：1978-01-09

    Applicant: CIBA GEIGY AG

    Inventor： DRABEK J ,  MEYER A

    IPC: A61K31/275 ,  C07C255/58 ,  A61P33/00 ,  C07C20060101 ,  C07C67/00 ,  C07C233/00 ,  C07C253/00 ,  C07C255/30 ,  C07C

    Abstract: This invention concerns novel anilinomethylenemalononitrile derivatives corresponding to the formula I (I) wherein R1 represents halogenalkyl containing 1 to 6 carbon atoms in the alkyl moiety, C3-C4 alkenyl, C3-C5 alkynyl or a benzyl radical which is unsubstituted or substituted by 1 to 2 halogen atoms, 1 to 2 C1-C2 alkyl radicals, or by a cyano or a trifluoromethyl group, R2 represents hydrogen, C1-C4 alkyl, halogen, the trifluoromethyl group, the nitro group or the cyano group, R3 represents hydrogen, halogen, the trifluoromethyl group or the nitro group, and R4 represents hydrogen or halogen, WITH THE PROVISO THAT, IF R1 represents the C3 alkynyl radical or the unsubstituted benzyl group, R2 and R3 may not be trifluoromethyl, compositions containing the novel compounds and the use of the novel compounds for combating helminths in domestic animals and productive livestock.

    6.
    发明专利
    未知

    公开(公告)号：DK9078A

    公开(公告)日：1978-07-11

    申请号：DK9078

    申请日：1978-01-09

    Applicant: CIBA GEIGY AG

    Inventor： DRABEK J ,  MEYER A

    IPC: A61K20060101 ,  A61K31/275 ,  C07C255/30 ,  C07C255/58 ,  A61K

    Abstract: This invention concerns anthelmintic compositions which contain as active component anilinomethylenemalononitrile derivatives corresponding to the formula wherein R1 represents hydrogen, C1-C6alkyl, the propargyl group or the benzyl radical, R2 represents hydrogen, C1-C4alkyl, halogen, the trifluoromethyl group, the nitro group or the cyano group, R3 represents hydrogen, halogen, the trifluoromethyl group or the nitro group, and R4 represents hydrogen or halogen, WITH THE PROVISO THAT R1 may only be the propargyl group or the benzyl radical if at least one of the symbols R2 or R3 represents the trifluoromethyl group, and the use of the compositions for combating helminths in domestic animals and productive livestock.

    9.
    发明专利
    未知

    公开(公告)号：DK159478A

    公开(公告)日：1978-10-13

    申请号：DK159478

    申请日：1978-04-11

    Applicant: CIBA GEIGY AG

    Inventor： GALLAY J J ,  KUEHNE M ,  MEYER A ,  RECHSTEINER O ,  SCHELLENBAUM M

    IPC: A61K31/415 ,  A61K31/4184 ,  A61P33/00 ,  A61P33/10 ,  C07D235/28 ,  C07D

    Abstract: Benzimidazole derivatives of the formula in which R is an alkyl group having 1 to 6 carbon atoms, an alkenyl group having 3 to 5 carbon atoms, an alkynyl group having 3 to 5 carbon atoms or a benzyl group, which is unsubstituted or monosubstituted to disubstituted by a methyl group, halogen or a nitro group; R1 is hydrogen, an alkanoyl group having 1 to 4 carbon atoms, an alkoxycarbonyl group having 1 to 4 carbon atoms, a N,N-dialkylcarbamoyl group or N,N-dialkylthiocarbamoyl group, each having 1 to 4 carbon atoms in the alkyl groups, an alkylsulphonyl group having 1 to 4 carbon atoms, a benzoyl group, a phenylsulphonyl group, a 4-methylphenylsulphonyl group or the radical, in which Q is a carbonyl group, a thiocarbonyl group or an oxalyl group; R2 is hydrogen, halogen or a methyl group; R3 is hydrogen, halogen, a methyl group or an alkoxy group having 1 to 4 carbon atoms; R4 is hydrogen, halogen or a methyl group; X is oxygen or sulphur; Y is halogen, an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms, a methylthio group, a methylsulphinyl group, a methylsulphonyl group, a trifluoromethyl group, a nitro group, a hydroxyl group, a cyano group or an alkanoyl group having 1 to 4 carbon atoms in the alkyl moiety m is 0, 1, 2 or 3; and n is 0, 1 or 2. Included are, if R1 is not hydrogen, the tautomeric compounds of the formula I. The compounds are effective for combating helminths in domestic and useful animals.

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