公开(公告)号：WO2017100116A1

公开(公告)日：2017-06-15

申请号：PCT/US2016/064903

申请日：2016-12-05

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： SCHAEFFER-KORBYLO, Lyndsay ,  MANUS, Lisa

IPC: A61K8/27 ,  A61K8/44 ,  A61Q11/02 ,  A61K33/00 ,  A61K31/198

CPC classification number: A61K8/58 ,  A61K8/27 ,  A61K8/44 ,  A61K2800/58 ,  A61Q11/00 ,  A61Q11/02 ,  A61K31/198 ,  A61K2300/00 ,  A61K33/30 ,  A61K33/34

Abstract: Disclosed herein are methods of promoting the aggregation and/or immune clearance of oral bacteria using oral care compositions comprising metal-amino acid complexes.

Abstract translation: 本文公开了使用包含金属 - 氨基酸复合物的口腔护理组合物促进口腔细菌的聚集和/或免疫清除的方法。

公开(公告)号：WO2015195124A1

公开(公告)日：2015-12-23

申请号：PCT/US2014/043051

申请日：2014-06-18

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： SZEWCZYK, Gregory ,  MANUS, Lisa ,  SCHAEFFER-KORBYLO, Lyndsay

IPC: A61K8/44 ,  A61K8/27 ,  A61K8/24 ,  A61Q11/00

CPC classification number: A61K8/24 ,  A61K8/21 ,  A61K8/25 ,  A61K8/27 ,  A61K8/44 ,  A61K8/442 ,  A61K8/463 ,  A61K2800/70 ,  A61Q11/00

Abstract: Disclosed herein are dentifrices comprising a zinc amino acid complex together with soluble phosphate salts. Methods of making and using the dentifrices are also provided.

Abstract translation: 本文公开了包含锌氨基酸复合物以及可溶性磷酸盐的洁齿剂。 还提供了制造和使用洁齿剂的方法。

公开(公告)号：EP3157502B1

公开(公告)日：2018-11-28

申请号：EP14736265.1

申请日：2014-06-18

Applicant: Colgate-Palmolive Company

Inventor： SZEWCZYK, Gregory ,  MANUS, Lisa ,  SCHAEFFER-KORBYLO, Lyndsay

IPC: A61K8/44 ,  A61K8/27 ,  A61K8/24 ,  A61Q11/00

CPC classification number: A61K8/24 ,  A61K8/21 ,  A61K8/25 ,  A61K8/27 ,  A61K8/44 ,  A61K8/442 ,  A61K8/463 ,  A61K2800/70 ,  A61Q11/00

Abstract: Disclosed herein are dentifrices comprising a zinc amino acid complex together with soluble phosphate salts. Methods of making and using the dentifrices are also provided.

公开(公告)号：EP3157934A1

公开(公告)日：2017-04-26

申请号：EP14737463.1

申请日：2014-06-18

Applicant: Colgate-Palmolive Company

Inventor： FITZGERALD, Michael ,  CONVERY, Joseph ,  MANUS, Lisa ,  TRIVEDI, Harsh

IPC: C07F3/00

CPC classification number: C07F3/06 ,  C07B2200/13 ,  C07F3/003

Abstract: The disclosure provides an improved synthesis for a zinc-lysine complex having the formula [Zn(C6H14N2O2)2Cl]+Cl−, in which a zinc compound selected from ZnO and ZnCl2, is reacted with a lysine compound selected from lysine and lysine.HCl, in aqueous acid. The disclosure also provides oral care and personal care compositions comprising the complex prepared by the synthesis, and methods of using these complexes and compositions.

Abstract translation: 本公开提供了具有式[Zn（C 6 H 14 N 2 O 2）2 Cl] + Cl-的锌 - 赖氨酸复合物的改进的合成，其中选自ZnO和ZnCl 2的锌化合物与选自赖氨酸和赖氨酸的赖氨酸化合物反应·HCl ，在含水酸中。 本公开还提供包含通过合成制备的复合物的口腔护理和个人护理组合物，以及使用这些复合物和组合物的方法。

公开(公告)号：EP4199883A1

公开(公告)日：2023-06-28

申请号：EP21815053.0

申请日：2021-11-03

Applicant: Colgate-Palmolive Company

Inventor： MANUS, Lisa ,  STEELE, Joseph ,  PICQUET, Guillaume ,  PADULA, Christine ,  CHEN, Dandan ,  WON, Betty ,  POTANIN, Andrei

IPC: A61K8/04 ,  A61K8/86 ,  A61P1/02 ,  A61Q11/00

公开(公告)号：EP3880192A1

公开(公告)日：2021-09-22

申请号：EP19836417.6

申请日：2019-12-16

Applicant: Colgate-Palmolive Company

Inventor： MANUS, Lisa ,  STRANICK, Michael ,  WU, Donghui

IPC: A61K31/198 ,  A61K33/30 ,  A61P1/00 ,  A61P1/02 ,  A61P1/04 ,  A61K9/00 ,  G01N33/00

公开(公告)号：EP3157934B1

公开(公告)日：2018-10-17

申请号：EP14737463.1

申请日：2014-06-18

Applicant: Colgate-Palmolive Company

Inventor： FITZGERALD, Michael ,  CONVERY, Joseph ,  MANUS, Lisa ,  TRIVEDI, Harsh

IPC: C07F3/00

CPC classification number: C07F3/06 ,  C07B2200/13 ,  C07F3/003

Abstract: The disclosure provides an improved synthesis for a zinc-lysine complex having the formula [Zn(C6H14N2O2)2Cl]+Cl−, in which a zinc compound selected from ZnO and ZnCl2, is reacted with a lysine compound selected from lysine and lysine.HCl, in aqueous acid. The disclosure also provides oral care and personal care compositions comprising the complex prepared by the synthesis, and methods of using these complexes and compositions.

公开(公告)号：EP3344346A1

公开(公告)日：2018-07-11

申请号：EP17735346.3

申请日：2017-06-23

Applicant: Colgate-Palmolive Company

Inventor： POTH, Tilo ,  POTANIN, Andrei ,  BLANVALET, Claude ,  WON, Betty ,  MANUS, Lisa ,  STRANICK, Michael A. ,  HUANG, Xiao Yi ,  PRENCIPE, Michael ,  RUSSO, Amy ,  STETTLER, Hansruedi ,  YAN, Peng ,  TAN, Chengkang ,  PATEL, Vyoma ,  MORGAN, Andre Michelle

IPC: A61Q11/00 ,  A61K8/27 ,  A61K8/44 ,  A61K8/73 ,  A61K8/24

Abstract: This invention relates to oral care compositions comprising arginine or lysine, zinc citrate and zinc oxide, fluoride source, and a silica abrasive which exhibits an acid pH when measured as an aqueous slurry as well as to methods of using and of making these compositions.

公开(公告)号：EP3283049A1

公开(公告)日：2018-02-21

申请号：EP16889671.0

申请日：2016-06-24

Applicant: Colgate-Palmolive Company

Inventor： PRENCIPE, Michael ,  RUSSO, Amy ,  STETTLER, Hansruedi ,  WON, Betty ,  MANUS, Lisa ,  STRANICK, Michael A. ,  YAN, Peng ,  TAN, Chengkang ,  PATEL, Vyoma ,  MORGAN, Andre Michelle ,  POTANIN, Andrei ,  HUANG, Xiaoyi

IPC: A61K8/44 ,  A61K8/27 ,  A61K8/25 ,  A61K8/21 ,  A61Q11/00

CPC classification number: A61K8/44 ,  A61K8/042 ,  A61K8/21 ,  A61K8/24 ,  A61K8/25 ,  A61K8/27 ,  A61K8/34 ,  A61K8/365 ,  A61K8/37 ,  A61K8/442 ,  A61K8/73 ,  A61K8/731 ,  A61K2800/28 ,  A61K2800/48 ,  A61K2800/52 ,  A61Q11/00

Abstract: Described herein are oral care compositions comprising a basic amino acid; a combination of zinc ion sources; and a thickening system comprising a nonionic cellulose ether having a viscosity, measured at 2% in water at 25° C., of 4500 to 7500 cps; and a polysaccharide gum; along with methods of making and using same.

公开(公告)号：EP4199891A1

公开(公告)日：2023-06-28

申请号：EP22711451.9

申请日：2022-03-03

Applicant: Colgate-Palmolive Company

Inventor： MANUS, Lisa ,  LEE, Jonghun ,  STEELE, Joseph ,  DENG, Yuzhi ,  XU, Shaopeng

IPC: A61K8/27 ,  A61K8/73 ,  A61Q11/00