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    ALUMINUM SALT CONTAINING HIGH PERCENTAGE OF AL30
    12.
    发明申请
    ALUMINUM SALT CONTAINING HIGH PERCENTAGE OF AL30 审中-公开
    含AL30高铝的铝盐

    公开(公告)号：WO2012061280A2

    公开(公告)日：2012-05-10

    申请号：PCT/US2011/058559

    申请日：2011-10-31

    Applicant: COLGATE-PALMOLIVE COMPANY ,  PAPPAS, Iraklis ,  VAUGHN, John ,  PAN, Long

    Inventor： PAPPAS, Iraklis ,  VAUGHN, John ,  PAN, Long

    IPC: A61Q15/00 ,  A61K8/26

    CPC classification number: C01F7/56 ,  A61K8/26 ,  A61K8/28 ,  A61K8/44 ,  A61K2800/592 ,  A61K2800/80 ,  A61Q15/00 ,  C01F7/002 ,  C01P2002/86 ,  C01P2002/87

    Abstract: A composition comprising an aluminum chlorohydrate salt, the aluminum chlorohydrate salt having at least 50 mole % Al 30 polyhydroxyoxoaluminum cation of all polyhydroxyoxoaluminum cations detectable by quantitative 27 Al NMR within the aluminum chlorohydrate salt, and a buffer. The composition can optionally include zirconium. Also disclosed are a method of making an aluminum salt using an increased molar concentration of a starting aluminum salt with a buffer, a method of reducing perspiration with the aluminum chlorohydrate salt, and a method of treating water with the aluminum chlorohydrate salt.

    Abstract translation: 一种包含氯化铝水合物盐的组合物，该水合氯化铝盐具有至少50摩尔％的所有聚羟基氧化铝阳离子的Al30聚羟基氧化铝阳离子，可通过铝水合盐内的定量27 Al NMR和缓冲液检测。 该组合物可以任选地包括锆。 还公开了使用起始铝盐与缓冲剂的摩尔浓度增加的方法，用氯化铝水合物盐减少汗水的方法以及用氯化铝水盐处理水的方法。

    ANTIPERSPIRANT ACTIVE COMPOSITIONS AND MANUFACTURE THEREOF
    13.
    发明申请
    ANTIPERSPIRANT ACTIVE COMPOSITIONS AND MANUFACTURE THEREOF 审中-公开
    抗菌活性组合物及其制备方法

    公开(公告)号：WO2012060817A1

    公开(公告)日：2012-05-10

    申请号：PCT/US2010/055030

    申请日：2010-11-02

    Applicant: COLGATE-PALMOLIVE COMPANY ,  PAPPAS, Iraklis ,  PAN, Long

    Inventor： PAPPAS, Iraklis ,  PAN, Long

    IPC: A61Q15/00 ,  A61K8/26

    CPC classification number: C01F7/56 ,  A61K8/26 ,  A61K8/28 ,  A61K8/44 ,  A61K2800/592 ,  A61K2800/80 ,  A61Q15/00 ,  C01F7/002 ,  C01P2002/86 ,  C01P2002/87

    Abstract: An antiperspirant active composition comprising an aluminum salt, the aluminum salt (i) having an aluminum to chloride molar ratio of 0.3:1 to 3:1; and (ii) exhibiting an 27 Al NMR spectrum with a species distribution including at least 90% A130 polyhydroxyoxoaluminum cation as the predominant species detectable by 27 Al NMR within the aluminum salt. The composition can optionally include zirconium. Also disclosed are a method of making an antiperspirant active composition and the use of a heating step at elevated temperature to convert Al 13 polyhydroxyoxoaluminum cations in the species detectable by 27 Al NMR within an aqueous aluminum salt solution into Al 30 polyhydroxyoxoaluminum cations in the species detectable by 27 Al NMR without increasing a SEC Peak 3 area in the SEC chromatogram of the aluminum salt.

    Abstract translation: 一种止汗活性组合物，其包含铝盐，所述铝盐（i）的铝与氯化物的摩尔比为0.3:1至3:1; 和（ii）显示具有包含至少90％的Al 3 O 3羟基氧化铝阳离子作为主要种类的物质分布的27Al NMR光谱，其可通过铝盐中的27Al NMR检测。 该组合物可以任选地包括锆。 还公开了制备止汗活性组合物的方法，并且在升高的温度下使用加热步骤将AlI 3聚羟基氧化铝阳离子转化成AlAl多羟基氧化铝阳离子，其可通过27Al NMR在铝盐水溶液中检测，可通过27Al NMR检测 而不增加铝盐的SEC色谱图中的SEC峰3区。

    METHOD OF MAKING AN ANHYDROUS LIQUID ANTIPERSPIRANT COMPOSITION
    19.
    发明申请
    METHOD OF MAKING AN ANHYDROUS LIQUID ANTIPERSPIRANT COMPOSITION 审中-公开
    制备无水液体抗菌组合物的方法

    公开(公告)号：WO2011087701A2

    公开(公告)日：2011-07-21

    申请号：PCT/US2010/060630

    申请日：2010-12-16

    Applicant: COLGATE-PALMOLIVE COMPANY ,  PAPPAS, Iraklis ,  FITZGERALD, Michael C. ,  PAN, Long

    Inventor： PAPPAS, Iraklis ,  FITZGERALD, Michael C. ,  PAN, Long

    IPC: A61Q15/00

    CPC classification number: A61K8/416 ,  A61K8/26 ,  A61K8/42 ,  A61K8/44 ,  A61K2800/31 ,  A61K2800/58 ,  A61Q15/00

    Abstract: A method of producing an anhydrous antiperspirant composition comprising (a) providing a mixture of at least one antiperspirant active including a metal salt, and an anhydrous carrier for the at least one antiperspirant active in which the at least one antiperspirant active is dissolved, the carrier comprising a eutectic mixture of at least one basic compound selected from a basic amide and a basic amine and at least one member chosen from a cation and zwitterion; and (b) heating the mixture to form a stabilized eutectic system of the at least one antiperspirant active and the anhydrous carrier. Also, an anhydrous antiperspirant composition.

    Abstract translation: 一种制备无水止汗组合物的方法，其包含（a）提供至少一种止汗剂活性物质（包括金属盐）的混合物和至少一种其中所述至少一种止汗活性剂溶解的止汗活性剂的无水载体，所述载体 包括至少一种选自碱性酰胺和碱性胺的碱性化合物和选自阳离子和两性离子的至少一种的共晶混合物; 和（b）加热混合物以形成至少一种止汗活性物质和无水载体的稳定的共晶体系。 另外，无水止汗组合物。

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