公开(公告)号：WO2021002910A1

公开(公告)日：2021-01-07

申请号：PCT/US2020/026844

申请日：2020-04-06

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： ZHANG, Shaoyi ,  TANG, Sadie ,  MYERS, Carl ,  XU, Guofeng

IPC: A61K8/19 ,  A61K8/21 ,  A61K8/24 ,  A61Q11/00

Abstract: This application relates to novel aqueous oral care compositions useful for combining and delivering incompatible stannous fluoride or stannous chloride and potassium salts in a high-water composition, for example, to provide effective caries prevention, protection against dental erosion, and relief from dental hypersensitivity. The compositions comprise stannous fluoride or stannous chloride, nitric acid or a water-soluble nitrate salt, a water-soluble alkali metal polyphosphate and more than 10% water, by weight of the composition.

公开(公告)号：WO2020131823A1

公开(公告)日：2020-06-25

申请号：PCT/US2019/066766

申请日：2019-12-17

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： MYERS, Carl ,  PAPPAS, Iraklis ,  HAO, Zhigang ,  TANG, Sadie

IPC: A61K8/19 ,  A61K8/20 ,  A61K8/21 ,  A61K8/24 ,  A61K8/27 ,  A61K8/365 ,  A61Q11/00 ,  A61K31/32

Abstract: Disclosed herein are high water oral care compositions comprising a stannous ion source, which compositions have improved stability. Methods of making and using the compositions are also provided.