公开(公告)号：ID21468A

公开(公告)日：1999-06-17

申请号：ID981592

申请日：1998-12-08

Applicant: DEGUSSA

Inventor： ESCH HEINZ ,  KUHLMANN ROBERT ,  NEUMULLER MATTHIAS ,  OTTO KARIN ,  RAUSCH RALF ,  THOMAS KLAUS-PETER

IPC: A61K8/21 ,  A61K8/25 ,  A61Q11/00 ,  B32B27/32

Abstract: A precipitated silica which contains an active substance with a characteristic, delayed release of active substance is prepared by adding the active substance during preparation of the precipitated silica. The precipitated silica containing the active substance may be added to oral hygiene agents such as toothpastes, topical fluoride preparations, dental materials or medicinal chewing gums.

公开(公告)号：NO942882A

公开(公告)日：1995-02-08

申请号：NO942882

申请日：1994-08-03

Applicant: DEGUSSA

Inventor： ESCH HEINZ ,  KUHLMANN ROBERT ,  NEUMULLER MATTHIAS ,  OTTO KARIN ,  RAUSCH RALF

IPC: A61K8/00 ,  A61K8/25 ,  A61Q11/00 ,  C01B33/193 ,  C01B33/18

CPC classification number: C01B33/193 ,  A61K8/25 ,  A61Q11/00 ,  C01P2004/61 ,  C01P2006/12 ,  C01P2006/22

公开(公告)号：DE3274796D1

公开(公告)日：1987-02-05

申请号：DE3274796

申请日：1982-02-26

Applicant: DEGUSSA

Inventor： MULLER KARL-HANS DR ,  NEUMULLER MATTHIAS ,  TURK GUNTER DR

IPC: A61K8/00 ,  A61K8/25 ,  A61K8/86 ,  A61Q11/00 ,  A61K7/16

Abstract: A dental-care composition having improved shelf life in respect of rheology and abrasiveness, which as a novel feature, contains, as a cleansing agent, a bifunctional (thickening and abrasive) precipitated silica characterized by the following physico-chemical properties: -Pendulum - roller - mill Jet mill -BET surface area m2/g 15-110 15-110 -Tamped density g/l 150-750 90-650 -Secondary particle size FIG. 1 FIG. 2 -distribution according to -Coulter Counter -"ALPINE" screen % by 63 mu m weight -Cu abrasion in 10% mg 5-30 5-30 -strength glycerol disper- -sion -Lightness value A % 86-96 90-96 -Viscosity in a 30% 30,000-60,000 30,000-60,000 -strength dispersion in a -1:1 glycerol/water -mixture, Brookfield RTV, -Sp5 - The dental-care composition may additionally contain 0.5-5% by weight of polyethylene glycol or 2-14% by weight of a precipitated silica which in 15% strength dispersion in a glycerol/water mixture has a viscosity of not less than 30,000 mPa.s. Pyrogenic silica can also be employed successfully to regulate the viscosity of the product.

公开(公告)号：BR8202033A

公开(公告)日：1983-03-22

申请号：BR8202033

申请日：1982-04-07

Applicant: DEGUSSA

Inventor： MULLER KARL HANS ,  NEUMULLER MATTHIAS ,  TURK GUNTHER

IPC: A61K8/00 ,  A61K8/25 ,  A61K8/86 ,  A61Q11/00 ,  A61K7/16

Abstract: A dental-care composition having improved shelf life in respect of rheology and abrasiveness, which as a novel feature, contains, as a cleansing agent, a bifunctional (thickening and abrasive) precipitated silica characterized by the following physico-chemical properties: -Pendulum - roller - mill Jet mill -BET surface area m2/g 15-110 15-110 -Tamped density g/l 150-750 90-650 -Secondary particle size FIG. 1 FIG. 2 -distribution according to -Coulter Counter -"ALPINE" screen % by 63 mu m weight -Cu abrasion in 10% mg 5-30 5-30 -strength glycerol disper- -sion -Lightness value A % 86-96 90-96 -Viscosity in a 30% 30,000-60,000 30,000-60,000 -strength dispersion in a -1:1 glycerol/water -mixture, Brookfield RTV, -Sp5 - The dental-care composition may additionally contain 0.5-5% by weight of polyethylene glycol or 2-14% by weight of a precipitated silica which in 15% strength dispersion in a glycerol/water mixture has a viscosity of not less than 30,000 mPa.s. Pyrogenic silica can also be employed successfully to regulate the viscosity of the product.