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公开(公告)号:CA2265777A1
公开(公告)日:1998-04-16
申请号:CA2265777
申请日:1997-09-29
Applicant: SWAN THOMAS & CO LTD , DEGUSSA
Inventor: TACKE THOMAS , SMAIL FIONA RUTH , WIELAND STEFAN , HITZLER MARTIN GEORG , SWAN THOMAS MACKLYN , ROSS STEPHEN KEITH , POLIAKOFF MARTYN
IPC: B01J31/06 , B01J3/00 , C07B37/02 , C07B37/04 , C07B41/06 , C07B61/00 , C07C2/66 , C07C2/70 , C07C2/86 , C07C15/02 , C07C41/30 , C07C43/205 , C07C45/46
Abstract: Method of performing alkylation or acylation reactions of aromatic substrates under supercritical or near-critical reaction conditions. In particular, a method of performing Friedel-Crafts alkylation or acylation reactions is disclosed under those conditions. Friedel-Crafts reactions may be effected using a heterogeneous catalyst in a continuous flow reactor containing a supercritical or near-critical reaction medium. Selectivity of product formation can be achieved by varying one or more of the temperature, pressure, catalyst, flow rates and also by varying the ratios of aromatic substrate to acylating or alkylating agent.
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公开(公告)号:NO20014268D0
公开(公告)日:2001-09-03
申请号:NO20014268
申请日:2001-09-03
Applicant: DEGUSSA
Inventor: POLIAKOFF MARTYN , ROSS STEPHEN KEITH , ROEDER STEFAN , GRAY WILLIAM KEITH , SWAN THOMAS MACKLYN , WIELAND STEFAN
IPC: C07C1/24 , C07C41/09 , C07C41/56 , C07D307/08 , C07D317/12 , C07C41/50
Abstract: The present invention relates to methods for inhibiting cathepsin K activity in a mammal in need thereof comprising administering a nitric oxide donor compound having cathepsin K inhibition activity. The present invention also relates to methods for inhibiting bone resorption in a mammal comprising administering to a mammal in need thereof a therapeutically effective amount of such a nitric oxide donor. The present invention also relates to compositions comprising such a nitric oxide donor.
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公开(公告)号:GB2357502A
公开(公告)日:2001-06-27
申请号:GB0102460
申请日:1999-06-30
Applicant: SWAN THOMAS & CO LTD , DEGUSSA
Inventor: POLIAKOFF MARTYN , MEEHAN NICOLA JANE , ROSS STEPHEN KEITH , WIELAND STEFAN , ROEDER STEFAN
Abstract: In a process for the hydroformylation of alkanes, alkenes or trialkylboranes under supercritical or near-critical conditions, hydroformylation is effected using a heterogeneous catalyst in a continuous flow reactor containing a supercritical or near-critical reaction medium. Selectivity of product formation may be achieved by independently varying one or more of the temperature, pressure, catalyst, mole ratios of hydrogen and carbon monoxide and flow rate.
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公开(公告)号:AU734245B2
公开(公告)日:2001-06-07
申请号:AU2516997
申请日:1997-04-11
Applicant: SWAN THOMAS & CO LTD , DEGUSSA
Inventor: POLIAKOFF MARTYN , SWAN THOMAS M , TACKE THOMAS , HITZLER MARTIN G , ROSS STEPHEN K , WIELAND STEFAN
IPC: B01J3/00 , C07B35/02 , C07B43/04 , C07B61/00 , C07C29/132 , C07C29/141 , C07C29/145 , C07C29/20 , C07C45/58 , C07C209/36 , C07D317/66
Abstract: PCT No. PCT/GB97/01014 Sec. 371 Date Feb. 18, 1999 Sec. 102(e) Date Feb. 18, 1999 PCT Filed Apr. 11, 1997 PCT Pub. No. WO97/38955 PCT Pub. Date Oct. 23, 1997Process for the selective hydrogenation of alphatic or aromatic substrates under supercritical or near critical conditions. Hydrogenation is effected using a heterogeneous catalyst in a continuous flow reactor containing a supercritical or near critical reaction medium and selectively of product formation is achieved by varying one or more of the temperature, pressure, catalyst and flow rate.
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公开(公告)号:NO20006712L
公开(公告)日:2001-03-01
申请号:NO20006712
申请日:2000-12-29
Applicant: SWAN THOMAS & CO LTD , DEGUSSA
Inventor: POLIAKOFF MARTYN , MEEHAN NICOLA JANE , ROSS STEPHEN KEITH , WIELAND STEFAN , ROEDER STEFAN
Abstract: In a process for the hydroformylation of alkanes, alkenes or trialkylboranes under supercritical or near-critical conditions, hydroformylation is effected using a heterogeneous catalyst in a continuous flow reactor containing a supercritical or near-critical reaction medium. Selectivity of product formation may be achieved by independently varying one of more of the temperature, pressure, catalyst, mole ratios of hydrogen and carbon monoxide and flow rate.
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公开(公告)号:NO20006712D0
公开(公告)日:2000-12-29
申请号:NO20006712
申请日:2000-12-29
Applicant: SWAN THOMAS & CO LTD , DEGUSSA
Inventor: POLIAKOFF MARTYN , MEEHAN NICOLA JANE , ROSS STEPHEN KEITH , WIELAND STEFAN , ROEDER STEFAN
Abstract: In a process for the hydroformylation of alkanes, alkenes or trialkylboranes under supercritical or near-critical conditions, hydroformylation is effected using a heterogeneous catalyst in a continuous flow reactor containing a supercritical or near-critical reaction medium. Selectivity of product formation may be achieved by independently varying one of more of the temperature, pressure, catalyst, mole ratios of hydrogen and carbon monoxide and flow rate.
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公开(公告)号:BR9712205A
公开(公告)日:1999-09-08
申请号:BR9712205
申请日:1997-09-29
Applicant: SWAN THOMAS & CO LTD , DEGUSSA , THOMAS M SWAN , THOMAS TACKE , MARTIN G HITZLER , STEPHEN K ROSS , STEFAN WIELAND , FIONA RUTH SMAIL
Inventor: POLIAKOFF MARTYN , AG DEGUSSA , SWAN THOMAS M , TACKE THOMAS , HITZLER MARTIN G , ROSS STEPHEN K , WIELAND STEFAN , SMAIL FIONA RUTH
IPC: B01J31/06 , B01J3/00 , C07B37/02 , C07B37/04 , C07B41/06 , C07B61/00 , C07C2/66 , C07C2/70 , C07C2/86 , C07C15/02 , C07C41/30 , C07C43/205 , C07C45/46
Abstract: A process for the alkylation of aromatic substrates under supercritical or near-critical reaction conditions is described. In particular, a method for performing Friedel-Crafts alkylation reactions is disclosed under those conditions. Friedel-Crafts reactions may be effected using a heterogeneous catalyst in a continuous flow reactor containing a supercritical or near-critical reaction medium. Selectivity of product formation can be achieved by varying one or more of temperature, pressure, catalyst, flow rates and also by varying the ratios of aromatic substrate to alkylating agent.
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公开(公告)号:NO991605D0
公开(公告)日:1999-03-31
申请号:NO991605
申请日:1999-03-31
Applicant: SWAN THOMAS & CO LTD , DEGUSSA
Inventor: SWAN THOMAS MACKLYN , ROSS STEPHEN KEITH , POLIAKOFF MARTYN , HITZLER MARTIN GEORG , SMAIL FIONA RUTH , TACKE THOMAS , WIELAND STEFAN
IPC: B01J3/00 , B01J31/06 , C07B37/02 , C07B37/04 , C07B41/06 , C07B61/00 , C07C2/66 , C07C2/70 , C07C2/86 , C07C15/02 , C07C41/30 , C07C43/205 , C07C45/46 , C07B
Abstract: A process for the alkylation of aromatic substrates under supercritical or near-critical reaction conditions is described. In particular, a method for performing Friedel-Crafts alkylation reactions is disclosed under those conditions. Friedel-Crafts reactions may be effected using a heterogeneous catalyst in a continuous flow reactor containing a supercritical or near-critical reaction medium. Selectivity of product formation can be achieved by varying one or more of temperature, pressure, catalyst, flow rates and also by varying the ratios of aromatic substrate to alkylating agent.
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公开(公告)号:ZA9703204B
公开(公告)日:1997-11-14
申请号:ZA9703204
申请日:1997-04-15
Applicant: SWAN THOMAS & CO LTD , DEGUSSA
Inventor: POLIAKOFF MARTYN , TACKE THOMAS , ROSS STEPHEN K , SWAN THOMAS M , HITZLER MARTIN G , WIELAND STEFAN
IPC: B01J3/00 , C07B35/02 , C07B43/04 , C07B61/00 , C07C29/132 , C07C29/141 , C07C29/145 , C07C29/20 , C07C45/58 , C07C209/36 , C07D317/66 , C07B , C10G
CPC classification number: C07C29/145 , B01J3/008 , C07B35/02 , C07B43/04 , C07C29/132 , C07C29/141 , C07C29/20 , C07C45/58 , C07C209/36 , C07C2601/14 , C07D317/66 , Y02P20/544 , C07C31/10 , C07C35/08 , C07C33/22 , C07C31/1355
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公开(公告)号:GB2357502B
公开(公告)日:2003-06-04
申请号:GB0102460
申请日:1999-06-30
Applicant: SWAN THOMAS & CO LTD , DEGUSSA
Inventor: POLIAKOFF MARTYN , MEEHAN NICOLA JANE , ROSS STEPHEN KEITH , WIELAND STEFAN , ROEDER STEFAN
Abstract: In a process for the hydroformylation of alkanes, alkenes or trialkylboranes under supercritical or near-critical conditions, hydroformylation is effected using a heterogeneous catalyst in a continuous flow reactor containing a supercritical or near-critical reaction medium. Selectivity of product formation may be achieved by independently varying one of more of the temperature, pressure, catalyst, mole ratios of hydrogen and carbon monoxide and flow rate.
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