公开(公告)号：SE7707266A

公开(公告)日：1977-12-26

申请号：SE7707266

申请日：1977-06-22

Applicant: HOECHST AG

Inventor： BARTMANN W ,  BECK G ,  LERCH U ,  SCHOLKENS B

IPC: A61K31/215 ,  A61P43/00 ,  C07C67/00 ,  C07C401/00 ,  C07C405/00 ,  C07C177/00

CPC classification number: C07C405/00

公开(公告)号：ZA7607520B

公开(公告)日：1977-11-30

申请号：ZA7607520

申请日：1976-12-17

Applicant: HOECHST AG

Inventor： REUSCHLING D ,  KUEHLEIN K ,  LINKIES A ,  BECK G ,  MUSIL J

IPC: C07D207/27 ,  A61K31/40 ,  A61K31/4015 ,  A61P43/00 ,  C07D207/26 ,  C07D ,  A61K

CPC classification number: C07D207/26 ,  Y10S514/929

公开(公告)号：ZA756949B

公开(公告)日：1977-06-29

申请号：ZA756949

申请日：1975-11-05

Applicant: HOECHST AG

Inventor： KUEHLEIN K ,  BARTMANN W ,  BECK G ,  REUSCHLING D ,  BABEJ M

IPC: C07D20060101 ,  C07D

公开(公告)号：DK572376A

公开(公告)日：1977-06-20

申请号：DK572376

申请日：1976-12-17

Applicant: HOECHST AG

Inventor： LINKIES A ,  REUSCHLING D B ,  KUEHLEIN K ,  BECK G ,  MUSIL J

IPC: C07D207/27 ,  A61K31/40 ,  A61K31/4015 ,  A61P43/00 ,  C07D207/26 ,  C07D

公开(公告)号：SE7613583A

公开(公告)日：1977-06-06

申请号：SE7613583

申请日：1976-12-03

Applicant: HOECHST AG

Inventor： BARTMANN W ,  BECK G ,  LERCH U ,  SEEGER K ,  TEUFEL H

IPC: A61K9/00 ,  A61K31/20 ,  A61P43/00 ,  C07C67/00 ,  C07C401/00 ,  C07C405/00 ,  C07D307/935 ,  C07F9/40 ,  C07C177/00

CPC classification number: C07D307/935 ,  C07C405/00 ,  C07F9/4006

公开(公告)号：ZA7603741B

公开(公告)日：1977-05-25

申请号：ZA7603741

申请日：1976-06-23

Applicant: HOECHST AG

Inventor： REUSCHLING D ,  KUEHLEIN K ,  TEIFEL H ,  BECK G ,  LERCH U ,  BARTMANN W ,  SCHOELKENS B ,  KUNSTMANN R

IPC: C07D207/26 ,  C07D207/27 ,  C07D

CPC classification number: C07D207/27

公开(公告)号：SE7607330L

公开(公告)日：1976-12-25

申请号：SE7607330

申请日：1976-06-24

Applicant: HOECHST AG

Inventor： REUSCHLING D-B ,  KUHLEIN K ,  SCHOLKENS B ,  KUNSTMANN R ,  LERCH U ,  BARTMANN W ,  TEUFEL H ,  BECK G

IPC: C07D207/26 ,  C07D207/27

Abstract: The present invention relates to pyrrolidones which are analogues of prostaglandins and to a process for their manufacture. The compounds of the invention have prostaglandin-like pharmacological properties and can therefore be used as pharmaceutical compositions.

公开(公告)号：DK281476A

公开(公告)日：1976-12-25

申请号：DK281476

申请日：1976-06-23

Applicant: HOECHST AG

Inventor： REUSCHLING D-B ,  KYHLEIN K ,  SCHOLKENS B ,  KUNSTMANN R ,  LERCH U ,  BARTMANN W ,  TEUFEL H ,  BECK G

IPC: C07D207/26 ,  C07D207/27 ,  C07D

Abstract: The present invention relates to pyrrolidones which are analogues of prostaglandins and to a process for their manufacture. The compounds of the invention have prostaglandin-like pharmacological properties and can therefore be used as pharmaceutical compositions.

公开(公告)号：ZA7504696B

公开(公告)日：1976-07-28

申请号：ZA7504696

申请日：1975-07-22

Applicant: HOECHST AG

Inventor： BECK G ,  BARTMANN W ,  LERCH U ,  SCHOELKENS B

IPC: A61K31/21 ,  A61K31/557 ,  A61K31/5575 ,  A61P43/00 ,  C07C67/00 ,  C07C271/28 ,  C07C401/00 ,  C07C405/00 ,  C07D307/935 ,  C07C ,  A61K

CPC classification number: C07C405/00

公开(公告)号：ZA753938B

公开(公告)日：1976-06-30

申请号：ZA753938

申请日：1975-06-19

Applicant: HOECHST AG

Inventor： TEUFEL H ,  BARTMANN W ,  BECK G ,  GRANZER A

IPC: A61K31/15 ,  A61K20060101 ,  C07C20060101 ,  C07C67/00 ,  C07C239/00 ,  C07C251/66 ,  A61K ,  C07C

Abstract: Procedure for the preparation of substituted 0-acyl acrylaldoximes of the formula I **(See formula)** where X represents a chlorine or bromine atom, R represents an alcoholic, alkoxy or alkylamino group, an alkenyl, alkenoxy or alkenylamino group each having 1 to 12 carbon atoms, or an aryl, aryloxy, arylalkyl group, arylalkoxy, arylamino or arylalkoxylaminos possibly substituted with one or two alcohol groups, each with 1 to 6 carbon atoms-, and R1, R2, R3 and R4 are the same or different and mean in each case a hydrogen atom, a halogen atom or an alcoholic or alkoxy group in each case with 1 to 6 carbon atoms, characterized in that the 2,3-diaryl-3-halogen-acryloxy compounds of formula II are acylated **(See formula)** wherein X, R1, R2, R3 and R4 have the meanings given in the description of formula I, in the presence of aprotic solvents with the aid of acylating agents, to form 0-acyl-2,3-diaryl-3- halogen-acryl-oximes of formula I. (Machine-translation by Google Translate, not legally binding)