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公开(公告)号：NZ201779A
公开(公告)日：1986-01-24
申请号：NZ20177982
申请日：1982-09-01
Applicant: HOECHST AG
Inventor： HENNING R , URBACH H , GEIGER R , TEETZ V , SCHOLKENS B
IPC: C07C275/16 , C07C67/00 , C07C239/00 , C07C275/24 , C07C279/14 , C07C301/00 , C07C303/40 , C07C311/30 , C07C313/00 , C07C315/04 , C07C317/50 , C07C323/44 , C07C323/57 , C07C323/59 , C07D207/16 , C07D207/22 , C07D209/20 , C07D209/42 , C07D209/52 , C07D211/60 , C07D213/55 , C07D217/12 , C07D217/26 , C07D223/06 , C07D231/12 , C07D233/54 , C07D277/06 , C07D333/24 , C07D333/60 , C07D401/12 , C07D403/12 , C07D409/12 , C07D471/04 , C07D495/04 , C07C127/00 , C07D217/00 , C07D209/00 , C07D233/00 , C07D207/00 , C07D211/00 , C07D333/00 , A61K31/17 , A61K31/38 , A61K31/40 , A61K31/47 , A61K31/415 , A61K31/445
Abstract: Compounds of the formula I I in which n denotes 0-3, R1 and R1' are the same or different and denote hydrogen, alkyl or alkenyl, phenyl or benzyl, each substituted as desired; R2 denotes hydrogen, alkyl or alkenyl; R3 denotes hydrogen, alkyl, hydroxyalkyl, alkoxyalkyl or aminoalkyl, alkanoylaminoalkyl, guanidinoalkyl, imidazolylalkyl, indolylalkyl, mercaptoalkyl or alkylthioalkyl, phenylalkyl, hydroxphenylalkyl, phenoxyalkyl or phenylthioalkyl, or R2 and R3, together with the C and N atoms carrying them, denote a saturated or unsaturated 4- to 8-membered monocyclic or 8- to 10-membered bicyclic isocycle or heterocycle, optionally monosubstituted or disubstituted by hydroxyl, alkoxy having 1 to 3 C atoms or alkyl, R4 denotes hydrogen, alkyl, alkenyl, alkadienyl, alkinyl, alkeninyl or alkadiinyl, cycloalkyl, phenyl, benzyl, phenethyl or phenylpropyl, each of which can be optionally monosubstituted or disubstituted; R5 denotes hydrogen or alkyl, hydroxyl or alkoxy and R6 denotes hydrogen, optionally substituted alkyl, cycloalkyl, alkenyl, optionally monosubstituted or disubstituted phenyl or naphthyl, their salts, a process for their preparation and their use as medicaments.
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公开(公告)号：NZ196316A
公开(公告)日：1984-08-24
申请号：NZ19631681
申请日：1981-02-20
Applicant: HOECHST AG
Inventor： BECK G , KNOLLE J , RUPP R H , SCHOLKENS B
IPC: A61K31/40 , A61K31/403 , A61P43/00 , C07D209/52 , C07D307/93 , C07D307/935 , C07D309/12 , C07D405/12 , C07D409/06 , C07D409/12 , C07D209 , A61K31/557
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公开(公告)号：SE7800689A
公开(公告)日：1978-07-22
申请号：SE7800689
申请日：1978-01-19
Applicant: HOECHST AG
Inventor： BARTMANN W , BECK G , LERCH U , TEUFEL H , SCHOLKENS B
IPC: C07D317/30 , A61K31/215 , A61K31/335 , A61K31/34 , A61K31/341 , A61K31/357 , A61P9/12 , A61P43/00 , C07C67/00 , C07C401/00 , C07C405/00 , C07D307/58 , C07C177/00
CPC classification number: C07C405/00
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公开(公告)号：SE7613948A
公开(公告)日：1977-06-14
申请号：SE7613948
申请日：1976-12-10
Applicant: HOECHST AG
Inventor： BARTMANN W , KUNSTMANN R , LERCH U , SCHOLKENS B
IPC: C07D207/27 , A61K31/40 , A61K31/4015 , A61P43/00 , C07D207/26
CPC classification number: C07D207/26
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公开(公告)号：SE7607331A
公开(公告)日：1976-12-28
申请号：SE7607331
申请日：1976-06-24
Applicant: HOECHST AG
Inventor： BARTMANN W , KUNSTMANN R , LERCH U , SCHOLKENS B
IPC: C07D207/27 , C07D207/26 , C07D498/04
CPC classification number: C07D207/26
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Patent Agency Ranking
公开(公告)号：SE7508380L
公开(公告)日：1976-01-26
申请号：SE7508380
申请日：1975-07-23
Applicant: HOECHST AG
Inventor： BECK G , BARTMANN W , LERCH U , SCHOLKENS B
IPC: A61K31/557 , A61K31/21 , A61K31/5575 , A61P43/00 , C07C67/00 , C07C271/28 , C07C401/00 , C07C405/00 , C07D307/935 , C07C177/00
Abstract: The present invention relates to new analogues which do not occur naturally of prostanoic acids of the formula I I The compounds of the invention have spasmogenic, bronchodilatant and hypotensive properties. Therefore, they can be used as medicaments. This invention also relates to a process for preparing the compounds of the invention.
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公开(公告)号：NZ213662A
公开(公告)日：1988-01-08
申请号：NZ21366282
申请日：1982-11-03
Applicant: HOECHST AG
Inventor： TEETZ V , GEIGER R , URBACH H , BECKER R , SCHOLKENS B
IPC: C07D209/52 , C07C101/00
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公开(公告)号：NZ202378A
公开(公告)日：1988-01-08
申请号：NZ20237882
申请日：1982-11-03
Applicant: HOECHST AG
Inventor： TEETZ V , GEIGER R , URBACH H , BECKER R , SCHOLKENS B
IPC: C07C227/08 , A61K31/40 , A61K31/403 , A61K38/00 , A61P9/12 , C07C227/10 , C07C227/16 , C07C229/28 , C07C229/36 , C07C237/06 , C07D209/52 , C07D451/04 , C07K5/02 , C07K5/06
Abstract: Compounds of the formula I (I) in which the carboxyl group on carbon atom 3 is orientated in the endo-position relative to the bicyclic ring system of cis-configuration, and in which R1 denotes hydrogen, allyl, vinyl or a side-chain of a naturally occurring alpha -aminoacid, which may be protected, R2 denotes hydrogen, alkyl, alkenyl or aralkyl, Y denotes hydrogen or hydroxyl and Z denotes hydrogen, or Y and Z together denote oxygen, and X denotes alkyl, alkenyl or cycloalkyl, or aryl which is optionally mono-, di- or tri-substituted by alkyl, alkoxy, hydroxyl, halogen, nitro, amino, alkylamino, dialkylamino or methylenedioxy, or denotes indol-3-yl, a process for their preparation, agents containing these compounds and their use.
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公开(公告)号：SE7800687L
公开(公告)日：1978-07-22
申请号：SE7800687
申请日：1978-01-19
Applicant: HOECHST AG
Inventor： BARTMANN W , BECK G , LERCH U , TEUFEL H , SCHOLKENS B
IPC: C07D307/42 , A61K31/20 , A61K31/34 , A61K31/341 , A61P1/00 , A61P9/12 , A61P11/08 , A61P13/02 , A61P15/00 , A61P43/00 , C07C67/00 , C07C401/00 , C07C405/00 , C07D307/54 , C07C177/00
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公开(公告)号：SE7800687A
公开(公告)日：1978-07-22
申请号：SE7800687
申请日：1978-01-19
Applicant: HOECHST AG
Inventor： BARTMANN W , BECK G , LERCH U , TEUFEL H , SCHOLKENS B
IPC: C07D307/42 , A61K31/20 , A61K31/34 , A61K31/341 , A61P1/00 , A61P9/12 , A61P11/08 , A61P13/02 , A61P15/00 , A61P43/00 , C07C67/00 , C07C401/00 , C07C405/00 , C07D307/54 , C07C177/00
CPC classification number: C07C405/00
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