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    11.
    发明专利
    未知

    公开(公告)号：DE3209149A1

    公开(公告)日：1983-10-06

    申请号：DE3209149

    申请日：1982-03-13

    Applicant: MAX PLANCK GESELLSCHAFT ,  HOECHST AG

    Inventor： TIMPL RUPERT DR ,  BROCKS DIETRICH DR ,  NEUBAUER HORST DR ,  STRECKER HELMUT DR

    IPC: G01N33/53 ,  A61K38/17 ,  A61K39/00 ,  A61K39/395 ,  G01N33/531 ,  G01N33/537 ,  G01N33/543 ,  G01N33/68 ,  C07G7/00 ,  G01N33/54

    Abstract: The antigens procollagen peptide (type (III) and procollagen peptide col 1 (type III) can be determined together immunologically by either (a) reacting a specified amount in each case of labeled procollagen peptide (type III) or procollagen peptide col 1 (type III) and a highly specific antiserum containing antibodies having affinity for both the antigens mentioned together with a sample having an unknown content of procollagen peptide (type III) and/or procollagen peptide col 1 (type III), separating off the antigen-antibody complex formed and measuring the amount of labeling in the complex and/or in the supernatant, or (b) bringing a specified amount of the highly specific antiserum to reaction with a sample having an unknown content of procollagen peptide (type III) and/or procollagen peptide col 1 (type III), fixing the unreacted amount of the antibody to procollagen peptide (type III) or procollagen peptide col 1 (type III) bound to a support, and bringing to reaction with a labeled second antibody, and then determining the amount of bound or excess second antibody by measuring the labeling. An anti-procollagen peptide col 1 (type III) serum is preferred as the highly specific serum, and this is obtained by using procollagen peptide col 1 (type III) for immunizing experimental animals and obtaining their serum.

    14.
    发明专利
    未知

    公开(公告)号：DE2800538A1

    公开(公告)日：1979-07-19

    申请号：DE2800538

    申请日：1978-01-07

    Applicant: HOECHST AG

    Inventor： STRECKER HELMUT DR ,  MOLTER MICHAEL DR ,  KLOSS GERHARD DR ,  SCHICKEL EBERHARD

    IPC: A61K51/00 ,  A61K51/04 ,  A61K29/00

    Abstract: A process is disclosed for the preparation of a diagnositc agent for scanning the RES, in particular the liver, by mixing the sodium salt of 1-phenyl-2,3-dimethyl-pyrazolone-4-methylamino-methylsulfonic acid or 1-phenyl-2,3-dimethyl-pyrazolone in aqueous solution with tin(II) salt, adjusting the solution to a pH between 4 and 9, optionally lyophilizing the mixture and adding 99mTc-pertechnetate in physiological saline solution.

    16.
    发明专利
    未知

    公开(公告)号：DE2236565A1

    公开(公告)日：1974-02-07

    申请号：DE2236565

    申请日：1972-07-26

    Applicant: HOECHST AG

    Inventor： STRECKER HELMUT DR ,  TETZLAFF KARL-HEINZ

    IPC: G21G4/08 ,  G21F5/00 ,  G21F7/06 ,  G21H5/00 ,  G21G1/00

    Abstract: Device for eluting nuclide generators comprising a nuclide generator, conveying means, container for eluting agent, and eluate container, wherein the container for the eluting agent, the eluate container and the conveying means are connected with the nuclide generator by conduits, the conveying means are mounted between the container for the eluting agent and the eluate container and the conveying means comprise a control mechanism which permits to convey freely chosen amounts of eluate into the eluate container.

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