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11.
公开(公告)号:HK1177501A1
公开(公告)日:2013-08-23
申请号:HK13104479
申请日:2013-04-12
Applicant: HOFFMANN LA ROCHE
Inventor: HORN CARINA , HEINDL DIETER , HAAR HANS-PETER , STEINKE NELLI
IPC: C12Q20060101
Abstract: In one form, a diagnostic element for determining at least one analyte is provided. In a further form, an analytical measuring device includes the diagnostic element. Still, other forms are related to methods for the determination of an analyte, correcting a signal generated by an analyte, and/or checking the detection optics of an analytical measuring device using the diagnostic element. Another form is related to a system for the controlled release of a reagent and the use of such a system as a circuit element. Other aspects include, but are not limited to, unique methods, techniques, products, systems and devices involving diagnostic elements.
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公开(公告)号:MX2012006445A
公开(公告)日:2012-06-28
申请号:MX2012006445
申请日:2010-12-10
Applicant: HOFFMANN LA ROCHE
Inventor: HORN CARINA , STEINKE NELLI
IPC: G01N33/50
Abstract: La invención se refiere a un elemento de diagnóstico y a un método para la producción del mismo.
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公开(公告)号:CA2770249A1
公开(公告)日:2011-02-24
申请号:CA2770249
申请日:2010-08-18
Applicant: HOFFMANN LA ROCHE
Inventor: ROEDEL WOLFGANG , HORN CARINA , STEINKE NELLI , BUCCI NADINE , MEIER THOMAS , SCHMUCK RAINER , NAGEL ROLF , HEINDL DIETER
Abstract: The present invention relates to a method for stabilizing an enzyme by storing an enzyme in the presence of a stabilized coenzyme. The present invention further relates to an enzyme stabilized with a stabilized coenzyme and to the use thereof in test elements for detecting analytes.
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公开(公告)号:CA2782031C
公开(公告)日:2015-08-11
申请号:CA2782031
申请日:2010-12-10
Applicant: HOFFMANN LA ROCHE
Inventor: HORN CARINA , STEINKE NELLI
IPC: G01N33/50
Abstract: The present invention concerns a sterilized diagnostic element and a process for the production thereof. The sterilized diagnostic element comprises a chemical detection reagent which comprises components that are sensitive to ionizing radiation, wherein the sterilized diagnostic element does not comprise a mediator, and the components that are sensitive to ionizing radiation are present in a functional form in a proportion of >= 80% based on the total amount of the respective component in the diagnostic element before sterilization, and wherein the components that are sensitive to ionizing radiation are an enzyme and a coenzyme.
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公开(公告)号:CA2770249C
公开(公告)日:2015-04-28
申请号:CA2770249
申请日:2010-08-18
Applicant: HOFFMANN LA ROCHE
Inventor: ROEDEL WOLFGANG , HORN CARINA , STEINKE NELLI , BUCCI NADINE , MEIER THOMAS , SCHMUCK RAINER , NAGEL ROLF , HEINDL DIETER
Abstract: The present invention concerns a method for stabilizing an enzyme by storing the enzyme in the presence of a stabilized coenzyme. In addition the present invention concerns an enzyme stabilized with a stabilized coenzyme as well as the use thereof in test elements for detecting analytes.
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公开(公告)号:ES2443576T3
公开(公告)日:2014-02-19
申请号:ES10790942
申请日:2010-12-10
Applicant: HOFFMANN LA ROCHE
Inventor: HORN CARINA , STEINKE NELLI
IPC: G01N33/50
Abstract: Elemento diagnóstico esterilizado que contiene un reactivo químico de detección con componentes sensiblesa la radiación ionizante, caracterizado porque el elemento diagnóstico esterilizado no lleva ningún mediador y los componentes sensibles a la radiación ionizanteestán respectivamente en forma funcional hasta un contenido >= 80%, sobre todo hasta un contenido >= 90%, respectoa la cantidad total del respectivo componente en el elemento diagnóstico antes de la esterilización, y porque loscomponentes sensibles a la radiación ionizante son un enzima y un coenzima.
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公开(公告)号:MX2012001946A
公开(公告)日:2012-04-02
申请号:MX2012001946
申请日:2010-08-18
Applicant: HOFFMANN LA ROCHE
Inventor: ROEDEL WOLFGANG , MEIER THOMAS , SCHMUCK RAINER , HEINDL DIETER , HORN CARINA , STEINKE NELLI , BUCCI NADINE , NAGEL ROLF
Abstract: La presente invención se relaciona con un método para estabilizar una enzima mediante almacenamiento de la enzima en presencia de una coenzima estabilizada. Además, la presente invención se relaciona con una enzima estabilizada con una coenzima estabilizada así como el uso de la misma en elementos de prueba para detectar analitos.
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