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    Stabilized cholinesterase substrate solution
    1.
    发明专利
    Stabilized cholinesterase substrate solution 有权
    稳定的胆碱酯底物溶液

    公开(公告)号：JP2007151553A

    公开(公告)日：2007-06-21

    申请号：JP2006331198

    申请日：2006-12-07

    Applicant: F Hoffmann La Roche Ag ,  エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft

    Inventor： GOTTSCHALK NORBERT ,  KYTZIA HANS-JOACHIM ,  MUECKE MATTHIAS ,  NAGEL ROLF ,  WEBER FRIEDERIKE

    IPC: C12Q1/46

    CPC classification number: C12Q1/46

    Abstract: PROBLEM TO BE SOLVED: To provide a method by which a dissolved cholinesterase substrate can be stored over a long time period. SOLUTION: The present invention relates to the use of a polar organic solvent for stabilizing a cholinesterase substrate solution, wherein at least one substrate is stabilized with at least one polar organic solvent in a buffered solution, to the use of the solution for measuring cholinesterase activity in a sample, to a stabilized cholinesterase substrate solution for measuring cholinesterase activity in a sample, wherein at least one substrate is stabilized by at least one polar organic solvent, to a method for measuring cholinesterase activity in a sample, to a kit for measuring cholinesterase activity in a sample, and to a kit for performing a method for measuring the cholinesterase activity. COPYRIGHT: (C)2007,JPO&INPIT

    Abstract translation: 待解决的问题：提供一种可以长时间储存​​溶解的胆碱酯酶底物的方法。 解决方案：本发明涉及极性有机溶剂用于稳定胆碱酯酶底物溶液的用途，其中至少一种底物在缓冲溶液中用至少一种极性有机溶剂稳定，以使用该溶液用于 将样品中的胆碱酯酶活性测量到用于测量样品中胆碱酯酶活性的稳定的胆碱酯酶底物溶液，其中至少一种底物通过至少一种极性有机溶剂稳定化，以测定样品中胆碱酯酶活性的方法， 用于测量样品中的胆碱酯酶活性，以及​​用于进行测量胆碱酯酶活性的方法的试剂盒。 版权所有（C）2007，JPO＆INPIT

    STABILIZED CHOLINESTERASE SUBTRATE SOLUTION
    4.
    发明专利
    STABILIZED CHOLINESTERASE SUBTRATE SOLUTION 未知

    公开(公告)号：CA2570660A1

    公开(公告)日：2007-06-08

    申请号：CA2570660

    申请日：2006-12-05

    Applicant: HOFFMANN LA ROCHE

    Inventor： MUECKE MATTHIAS ,  GOTTSCHALK NORBERT ,  WEBER FRIEDERIKE ,  KYTZIA HANS-JOACHIM ,  NAGEL ROLF

    IPC: C12Q1/46 ,  C07B63/00

    Abstract: The present invention relates to the use of a polar organic solvent for the stabilization of a cholinesterase substrate solution, wherein at least one substrate is stabilized by at least one species of a polar organic solvent in a buffered solution, and to the use of said solution for determining the activity of cholinesterase in a sample. Al so within the scope of the present invention is a stabilized cholinesterase substrate solution for determining the activity of a cholinesterase in a sample, wherein at least o ne substrate is stabilized by at least one species of a polar organic solvent. Furthermore, the invention relates to a method for determining the activity of a cholinesterase in a sample, as well as a kit for determining the activity of a cholinesterase in a sample and a kit for conducting a method for determining the activity of a cholinesterase in a sample.

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