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公开(公告)号:ES2187524T3
公开(公告)日:2003-06-16
申请号:ES94919184
申请日:1994-05-19
Applicant: IMARX PHARMACEUTICAL CORP
Inventor: UNGER EVAN C , FRITZ THOMAS A , MATSUNAGA TERRY , RAMASWAMI VARADARAJAN , YELLOWHAIR DAVID , WU GUANLI
IPC: A61B8/00 , A61K8/14 , A61K9/127 , A61K41/00 , A61K47/48 , A61K48/00 , A61K49/00 , A61K49/18 , A61K49/22 , A61M5/31 , A61Q19/00 , B01J13/02
Abstract: Methods of and apparatus for preparing gas-filled liposomes are described. Gas-filled liposomes prepared by these methods are particularly useful, for example, in ultrasonic imaging applications and in therapeutic drug delivery systems.
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公开(公告)号:DE69431753D1
公开(公告)日:2003-01-02
申请号:DE69431753
申请日:1994-05-19
Applicant: IMARX PHARMACEUTICAL CORP
Inventor: UNGER EVAN C , FRITZ THOMAS A , MATSUNAGA TERRY , RAMASWAMI VARADARAJAN , YELLOWHAIR DAVID , WU GUANLI
IPC: A61B8/00 , A61K8/14 , A61K9/127 , A61K41/00 , A61K47/48 , A61K48/00 , A61K49/00 , A61K49/18 , A61K49/22 , A61M5/31 , A61Q19/00 , B01J13/02
Abstract: Methods of and apparatus for preparing gas-filled liposomes are described. Gas-filled liposomes prepared by these methods are particularly useful, for example, in ultrasonic imaging applications and in therapeutic drug delivery systems.
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公开(公告)号:AU713127B2
公开(公告)日:1999-11-25
申请号:AU5627198
申请日:1998-02-24
Applicant: IMARX PHARMACEUTICAL CORP
Inventor: UNGER EVAN C , FRITZ THOMAS A , MATSUNAGA TERRY , RAMASWAMI VARADARAJAN , YELLOWHAIR DAVID , WU GUANLI
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公开(公告)号:AU8840698A
公开(公告)日:1999-02-04
申请号:AU8840698
申请日:1998-10-09
Applicant: IMARX PHARMACEUTICAL CORP
Inventor: UNGER EVAN C , FRITZ THOMAS A , MATSUNAGA TERRY , RAMASWAMI VARADARAJAN , YELLOWHAIR DAVID , WU GUANLI
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公开(公告)号:AU7041694A
公开(公告)日:1995-01-03
申请号:AU7041694
申请日:1994-05-19
Applicant: IMARX PHARMACEUTICAL CORP
Inventor: UNGER EVAN C , FRITZ THOMAS A , MATSUNAGA TERRY , RAMASWAMI VARADARAJAN , YELLOWHAIR DAVID , WU GUANLI
IPC: A61B8/00 , A61K8/14 , A61K9/127 , A61K41/00 , A61K47/48 , A61K48/00 , A61K49/00 , A61K49/18 , A61K49/22 , A61M5/31 , A61Q19/00 , B01J13/02
Abstract: Methods of and apparatus for preparing gas-filled liposomes are described. Gas-filled liposomes prepared by these methods are particularly useful, for example, in ultrasonic imaging applications and in therapeutic drug delivery systems.
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公开(公告)号:ES2193161T3
公开(公告)日:2003-11-01
申请号:ES94919208
申请日:1994-05-20
Applicant: IMARX PHARMACEUTICAL CORP
Inventor: UNGER EVAN C , FRITZ THOMAS A , MATSUNAGA TERRY , RAMASWAMI VARADARAJAN , YELLOWHAIR DAVID , WU GUANLI
IPC: A61B8/00 , A61K8/14 , A61K9/127 , A61K41/00 , A61K47/48 , A61K49/00 , A61K49/18 , A61K49/22 , A61M5/31 , A61Q19/00 , B01J13/02
Abstract: Methods of and apparatus for preparing temperature activated gaseous precursor-filled liposomes are described. Gaseous precursor-filled liposomes prepared by these methods are particularly useful, for example, in ultrasonic imaging applications and in therapeutic drug delivery systems.
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公开(公告)号:DE69432219D1
公开(公告)日:2003-04-10
申请号:DE69432219
申请日:1994-05-20
Applicant: IMARX PHARMACEUTICAL CORP
Inventor: UNGER EVAN C , FRITZ THOMAS A , MATSUNAGA TERRY , RAMASWAMI VARADARAJAN , YELLOWHAIR DAVID , WU GUANLI
IPC: A61B8/00 , A61K8/14 , A61K9/127 , A61K41/00 , A61K47/48 , A61K49/00 , A61K49/18 , A61K49/22 , A61M5/31 , A61Q19/00 , B01J13/02
Abstract: Methods of and apparatus for preparing temperature activated gaseous precursor-filled liposomes are described. Gaseous precursor-filled liposomes prepared by these methods are particularly useful, for example, in ultrasonic imaging applications and in therapeutic drug delivery systems.
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公开(公告)号:AT227960T
公开(公告)日:2002-12-15
申请号:AT94919184
申请日:1994-05-19
Applicant: IMARX PHARMACEUTICAL CORP
Inventor: UNGER EVAN C , FRITZ THOMAS A , MATSUNAGA TERRY , RAMASWAMI VARADARAJAN , YELLOWHAIR DAVID , WU GUANLI
IPC: A61B8/00 , A61K8/14 , A61K9/127 , A61K41/00 , A61K47/48 , A61K48/00 , A61K49/00 , A61K49/18 , A61K49/22 , A61M5/31 , A61Q19/00 , B01J13/02
Abstract: Methods of and apparatus for preparing gas-filled liposomes are described. Gas-filled liposomes prepared by these methods are particularly useful, for example, in ultrasonic imaging applications and in therapeutic drug delivery systems.
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公开(公告)号:AU2451097A
公开(公告)日:1997-11-19
申请号:AU2451097
申请日:1997-04-02
Applicant: IMARX PHARMACEUTICAL CORP
Inventor: UNGER EVAN C , FRITZ THOMAS , MATSUNAGA TERRY , RAMASWAMI VARADARAJAN , YELLOWHAIR DAVID , WU GUANLI
IPC: A61B8/08 , A61K8/14 , A61K9/127 , A61K41/00 , A61K47/30 , A61K47/48 , A61K49/00 , A61K49/04 , A61K49/18 , A61K49/22 , A61M5/31 , A61Q19/00 , B01J13/02 , G01R33/28 , A61B8/13
Abstract: Lyophilized lipid compositions, as well as methods for their preparation, are embodied by the present invention. Gas-filled microspheres prepared using the lyophilized lipid composition are particularly useful, for example, in ultrasonic imaging applications and in therapeutic drug delivery systems.
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公开(公告)号:CA2164846A1
公开(公告)日:1994-12-22
申请号:CA2164846
申请日:1994-05-19
Applicant: IMARX PHARMACEUTICAL CORP
Inventor: RAMASWAMI VARADARAJAN , UNGER EVAN C , WU GUANLI , YELLOWHAIR DAVID , MATSUNAGA TERRY , FRITZ THOMAS A
IPC: A61K8/14 , A61K9/127 , A61K9/14 , A61K41/00 , A61K47/48 , A61K49/04 , A61K49/18 , A61K49/22 , A61M5/31 , A61Q19/00 , B28B1/54 , A61K9/16 , A61K31/70 , A61K38/17 , A61K38/19 , A61K39/00 , A61K39/395 , A61K48/00 , A61N2/00 , A61N5/00 , A61N7/00 , B01J13/02
Abstract: Therapeutic delivery systems comprising gaseous precursor-filled microspheres comprising a therapeutic are described. Methods for employing such microspheres in therapeutic delivery applications are also provided. Therapeutic delivery systems comprising gaseous precursor-filled liposomes having encapsulated therein a contrast agent or drug are preferred. Methods of and apparatus for preparing such liposomes and methods for employing such liposomes in therapeutic delivery applications are also disclosed.
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