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公开(公告)号：CA2699707C
公开(公告)日：2016-05-17
申请号：CA2699707
申请日：2008-09-19
Applicant: JANSSEN PHARMACEUTICA NV
Inventor： STORCK PIERRE-HENRI , SCHOENTJES BRUNO , PIETTRE ARNAUD MARCEL PIERRE , ERMERT PHILIPP , PONCELET VIRGINIE SOPHIE , CSOKA IMRE CHRISTIAN FRANCIS
IPC: C07D413/14 , A61K31/538 , A61P35/00
Abstract: The present invention provides compounds of formula (I), their use as an inhibitor of a p53-MDM2 interaction as well as pharmaceutical compositions comprising said compounds: wherein n, s, t, R1, R2, R3, R4, R5, X, Y, Q, Z, G, E and D have defined meanings.
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公开(公告)号：DK2271626T3
公开(公告)日：2015-02-23
申请号：DK09725177
申请日：2009-03-26
Applicant: JANSSEN PHARMACEUTICA NV
Inventor： ANGIBAUD PATRICK RENÉ , MEVELLEC LAURENCE ANNE , ROUX BRUNO , STORCK PIERRE-HENRI , MEYER CHRISTOPHE , VIALARD JORGE EDUARDO
IPC: C07D221/12 , A61K31/473 , A61P35/00 , C07D401/06
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公开(公告)号：PL2215075T3
公开(公告)日：2014-04-30
申请号：PL08841176
申请日：2008-10-22
Applicant: JANSSEN PHARMACEUTICA NV
Inventor： ANGIBAUD PATRICK RENÉ , MARCONNET-DECRANE LAURENCE FRANÇOISE BERNADETTE , VIALARD JORGE EDUARDO , MEVELLEC LAURENCE ANNE , MEYER CHRISTOPHE , STORCK PIERRE-HENRI
IPC: C07D401/06 , A61K31/4704 , A61P25/00 , A61P35/00 , C07D215/227 , C07D401/10 , C07D401/12 , C07D401/14 , C07D487/08
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公开(公告)号：JO2704B1
公开(公告)日：2013-03-03
申请号：JOP20080406
申请日：2008-09-11
Applicant: JANSSEN PHARMACEUTICA NV
Inventor： PONCELET VIRGINIE SOPHIE , COUPA SOPHIE , STORCK PIERRE-HENRI , SCHOENTJES BRUNO
Abstract: The present invention provides compounds of formula (I), their use as an inhibitor of a p53-MDM2 interaction as well as pharmaceutical compositions comprising said compounds: wherein n, m, p, s, t, R1, R2, R3, R4, R5, R6, R7, R20, X, Y, Q and Z have defined meanings.
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公开(公告)号：DK2134691T3
公开(公告)日：2012-05-07
申请号：DK08717511
申请日：2008-03-07
Applicant: JANSSEN PHARMACEUTICA NV
Inventor： VIALARD JORGE EDUARDO , ANGIBAUD PATRICK RENE , MEVELLEC LAURENCE ANNE , MEYER CHRISTOPHE , FREYNE EDDY JEAN EDGARD , PILATTE ISABELLE NOELLE CONSTANCE , ROUX BRUNO , PASQUIER ELISABETH THERESE JEANNE , BOURDREZ XAVIER MARC , ADELINET CHRISTOPHE DENIS , MARCONNET-DECRANE LAURENCE FRANCOISE BERNADETTE , MACRITCHIE JACQUELINE ANNE , DUFFY JAMES EDWARD STEWART , OWENS ANDREW PATE , STORCK PIERRE-HENRI , PONCELET VIRGINIE SOPHIE
IPC: C07D215/22 , A61K31/4704
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Patent Agency Ranking
公开(公告)号：AT547415T
公开(公告)日：2012-03-15
申请号：AT08804483
申请日：2008-09-19
Applicant: JANSSEN PHARMACEUTICA NV
Inventor： STORCK PIERRE-HENRI , SCHOENTJES BRUNO , PIETTRE ARNAUD MARCEL PIERRE , ERMERT PHILIPP , PONCELET VIRGINIE SOPHIE , CSOKA IMRE CHRISTIAN FRANCIS
IPC: C07D413/14 , A61K31/538 , A61P35/00
Abstract: The present invention provides compounds of formula (I), their use as an inhibitor of a p53-MDM2 interaction as well as pharmaceutical compositions comprising said compounds: wherein n, s, t, R1, R2, R3, R4, R5, X, Y, Q, Z, G, E and D have defined meanings.
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公开(公告)号：HK1151796A1
公开(公告)日：2012-02-10
申请号：HK11105902
申请日：2011-06-10
Applicant: JANSSEN PHARMACEUTICA NV
Inventor： ANGIBAUD PATRICK RENE , MEVELLEC LAURENCE ANNE , ROUX BRUNO , STORCK PIERRE-HENRI , MEYER CHRISTOPHE , VIALARD JORGE EDUARDO
IPC: C07D20060101 , A61K20060101 , A61P20060101
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公开(公告)号：SI2203440T1
公开(公告)日：2011-07-29
申请号：SI200830267
申请日：2008-09-18
Applicant: JANSSEN PHARMACEUTICA NV
Inventor： PONCELET VIRGINIE SOPHIE , COUPA SOPHIE , STORCK PIERRE-HENRI , SCHOENTJES BRUNO
IPC: C07D401/00 , A61K31/403 , A61P29/00 , A61P35/00
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公开(公告)号：CA2716726A1
公开(公告)日：2009-10-01
申请号：CA2716726
申请日：2009-03-26
Applicant: JANSSEN PHARMACEUTICA NV
Inventor： ANGIBAUD PATRICK RENE , MEVELLEC LAURENCE ANNE , ROUX BRUNO , STORCK PIERRE-HENRI , MEYER CHRISTOPHE , VIALARD JORGE EDUARDO
IPC: C07D221/12 , A61K31/473 , A61P35/00 , C07D401/06
Abstract: The present invention provides compounds of formula (I), their use as inhibitors of tubulin polymerization and their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of Formula (I) wherein R1, R2, R3, R 4, R5, R6, R7 and Y have defined meanings.
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公开(公告)号：CA2699707A1
公开(公告)日：2009-03-26
申请号：CA2699707
申请日：2008-09-19
Applicant: JANSSEN PHARMACEUTICA NV
Inventor： STORCK PIERRE-HENRI , SCHOENTJES BRUNO , PIETTRE ARNAUD MARCEL PIERRE , ERMERT PHILIPP , PONCELET VIRGINIE SOPHIE , CSOKA IMRE CHRISTIAN FRANCIS
IPC: C07D413/14 , A61K31/538 , A61P35/00
Abstract: The present invention provides compounds of formula (I), their use as an inhibitor of a p53-MDM2 interaction as well as pharmaceutical compositions comprising said compounds: wherein n, s, t, R1, R2, R3, R4, R5, X, Y, Q, Z, G, E and D have defined meanings.
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