公开(公告)号：DE3665580D1

公开(公告)日：1989-10-19

申请号：DE3665580

申请日：1986-12-10

Applicant: KAO CORP

Inventor： KAWAMATA AKIRA ,  YANO SHINJI ,  HATTORI MICHIHIRO ,  AKAZAKI SHUICHI ,  IMOKAWA GENJI ,  TAKAISHI NAOTAKE

IPC: A61K8/68 ,  A61Q19/00 ,  C09K23/22 ,  F16K31/18 ,  C07C103/38 ,  C07C103/60 ,  A61K31/16

Abstract: An external medicament comprises a novel amide derivative represented by the following formula (I).wherein R 1 and R 2 are long chain alkyl groups.The external medicament is applicable to both a pharmaceutical external medicament and a cosmetic composition, and it provides excellent improving and preventing effects for chapping of the skin.

公开(公告)号：PH22844A

公开(公告)日：1989-01-19

申请号：PH24630D

申请日：1986-12-19

Applicant: KAO CORP

Inventor： AKIRA KAWAMATA ,  YANO SHINJI ,  HATTORI MICHIHIRO ,  AKAZAKI SHUICHI ,  IMOKAWA GENJI ,  TAKAISHI NAOTAKE

IPC: A61K8/68 ,  A61Q19/00 ,  C09K23/22 ,  F16K31/18 ,  C07C103/60

Abstract: An external medicament comprises a novel amide derivative represented by the following formula (I).wherein R 1 and R 2 are long chain alkyl groups.The external medicament is applicable to both a pharmaceutical external medicament and a cosmetic composition, and it provides excellent improving and preventing effects for chapping of the skin.

公开(公告)号：DE3441636C2

公开(公告)日：1994-10-20

申请号：DE3441636

申请日：1984-11-14

Applicant: KAO CORP

Inventor： IMOKAWA GENJI ,  TAKAISHI NAOTAKE ,  TEJIMA TOHRU ,  NAKAMURA KOICHI ,  HATTORI MICHIHIRO ,  MASUDA SHINICHI

IPC: C07C69/28 ,  A61K8/00 ,  A61K8/33 ,  A61K8/37 ,  A61K31/235 ,  A61Q17/04 ,  C07C69/017 ,  C07C69/035 ,  C07C69/24 ,  C07C69/527 ,  C07C69/533 ,  C09K3/00 ,  A61K7/42

公开(公告)号：HK41493A

公开(公告)日：1993-05-07

申请号：HK41493

申请日：1993-04-29

Applicant: KAO CORP

Inventor： NAKAMURA KOICHI ,  HATTORI MICHIHIRO ,  TAMURA TADASHI ,  TEJIMA TOHRU ,  TAKAISHI NOATAKE ,  IMOKAWA GENJI

IPC: A61K8/00 ,  A61K8/33 ,  A61K8/36 ,  A61K8/368 ,  A61K8/37 ,  A61K8/39 ,  A61Q1/00 ,  A61Q1/02 ,  A61Q1/04 ,  A61Q1/06 ,  A61Q1/12 ,  A61Q17/04 ,  A61Q19/08 ,  C07C65/34 ,  C07C65/40 ,  C09K3/00 ,  A61K7/44

Abstract: A composition for application to the skin to protect the skin from the long wavelength ultraviolet ray comprises a dibenzoylmethane derivative of the following general formulain which X represents a hydrogen atom, a monovalent metal cation, an organic cation, a linear or branched alkyl group having from 1 to 24 carbon atoms, or a polyoxyalkylene oxide having 2 or 3 carbon atoms, each Y and each Z independently represent a hydroxyl group, a linear or branched alkyl group having from 1 to 24 carbon atoms, or an alkoxy group having from 1 to 24 carbon atoms, or a polyoxyalkylene oxide group having from 2 to 3 carbon atoms, and m and n are independently an integer of from 0 to 3.The composition is adjustable so as to have an optimum HLB balance and has good compatibility with various cosmetic bases. Further, it does not irritate the skin, is difficult to be percutaneously absorbed and shows continued skin-protecting effects.

公开(公告)号：DE3480171D1

公开(公告)日：1989-11-23

申请号：DE3480171

申请日：1984-06-13

Applicant: KAO CORP

Inventor： YAMAMOTO HIROMI ,  OKUMURA TAKEO ,  EGUCHI YASUTERU ,  HATTORI MICHIHIRO

IPC: A61K8/19 ,  A61Q7/00 ,  A61K7/06

Abstract: A hair growth promoting composition comprising a solution of a blood flow increasing agent and/or a hair matrix cell activator in admixture with carbon dioxide gas. The incorporation of carbon dioxide is effective in increasing the blood flow and also in vasodilating of capillary vessels in the scalp with the hair matrix cell activator efficiently arriving at the hair matrix cells and serving to activate the cells. Thus, the composition according to the invention leads to reduction of falling-out of the hair and promotion of hair growth. The composition is served as tightly sealed in a pressure-resistant container.

公开(公告)号：AT47310T

公开(公告)日：1989-11-15

申请号：AT84106744

申请日：1984-06-13

Applicant: KAO CORP

Inventor： YAMAMOTO HIROMI ,  OKUMURA TAKEO ,  EGUCHI YASUTERU ,  HATTORI MICHIHIRO

IPC: A61K7/06

公开(公告)号：FR2585568A1

公开(公告)日：1987-02-06

申请号：FR8609998

申请日：1986-07-09

Applicant: KAO CORP

Inventor： HATTORI MICHIHIRO ,  AKAZAKI SHUICHI ,  YOSHIZUKA NAONOBU ,  IMOKAWA GENJI

IPC: A61K8/96 ,  A61K8/00 ,  A61K8/06 ,  A61K8/34 ,  A61K8/92 ,  A61K8/98 ,  A61K31/00 ,  A61K35/36 ,  A61Q19/00 ,  A61K7/48

公开(公告)号：GB2149789A

公开(公告)日：1985-06-19

申请号：GB8427998

申请日：1984-11-06

Applicant: KAO CORP

Inventor： TEJIMA TOHRU ,  NAKAMURA KOICHI ,  HATTORI MICHIHIRO ,  MASUDA SHINICHI ,  IMOKAWA GENJI ,  TAKAISHA NAOTAKE

IPC: C07C69/28 ,  A61K8/00 ,  A61K8/33 ,  A61K8/37 ,  A61K31/235 ,  A61Q17/04 ,  C07C69/017 ,  C07C69/035 ,  C07C69/24 ,  C07C69/527 ,  C07C69/533 ,  C09K3/00 ,  A61K7/42

公开(公告)号：FR2555167A1

公开(公告)日：1985-05-24

申请号：FR8417487

申请日：1984-11-16

Applicant: KAO CORP

Inventor： TEJIMA TOHRU ,  NAKAMURA KOICHI ,  HATTORI MICHIHIRO ,  MASUDA SHINICHI ,  IMOKAWA GENJI ,  TAKAISHI NAOTAKE

IPC: C07C69/28 ,  A61K8/00 ,  A61K8/33 ,  A61K8/37 ,  A61K31/235 ,  A61Q17/04 ,  C07C69/017 ,  C07C69/035 ,  C07C69/24 ,  C07C69/527 ,  C07C69/533 ,  C09K3/00 ,  A61K7/42

公开(公告)号：HK34191A

公开(公告)日：1991-05-10

申请号：HK34191

申请日：1991-05-02

Applicant: KAO CORP

Inventor： YAMAMOTO HIROMI ,  OKUMURA TAKEO ,  EGUCHI YASUTERU ,  HATTORI MICHIHIRO

IPC: A61K8/19 ,  A61Q7/00 ,  A61K7/06

Abstract: A hair growth promoting composition comprising a solution of a blood flow increasing agent and/or a hair matrix cell activator in admixture with carbon dioxide gas. The incorporation of carbon dioxide is effective in increasing the blood flow and also in vasodilating of capillary vessels in the scalp with the hair matrix cell activator efficiently arriving at the hair matrix cells and serving to activate the cells. Thus, the composition according to the invention leads to reduction of falling-out of the hair and promotion of hair growth. The composition is served as tightly sealed in a pressure-resistant container.