公开(公告)号：WO9412490A3

公开(公告)日：1994-07-21

申请号：PCT/JP9301676

申请日：1993-11-16

Applicant: KAO CORP ,  OHASHI YUKIHIRO ,  KAWAMATA AKIRA ,  YADA YUKIHIRO ,  HIGUCHI KAZUHIKO ,  TSUKAHARA KAZUE ,  IMOKAWA GENJI

Inventor： OHASHI YUKIHIRO ,  KAWAMATA AKIRA ,  YADA YUKIHIRO ,  HIGUCHI KAZUHIKO ,  TSUKAHARA KAZUE ,  IMOKAWA GENJI

IPC: A61K8/68 ,  A61Q19/00 ,  C07D317/24 ,  C07D317/30 ,  A61K7/48 ,  C07C237/22 ,  C07D317/22

CPC classification number: C07D317/30 ,  A61K8/68 ,  A61Q19/00 ,  C07D317/24

Abstract: The amide derivative of the present invention is one represented by general formula (I) or (II). The dermatologic preparation of the present invention is one containing said amide derivative. In formula (I), R1 represents a straight-chain or branched, saturated or unsaturated hydrocarbon group carrying 10 to 40 carbon atoms; R2 represents a straight-chain or branched, saturated or unsaturated hydrocarbon group carrying 3 to 39 carbon atoms; R3 represents a group containing at least one group represented by formula (A), wherein R?4 and R5¿ each represents a hydrogen atom or a straight-chain or branched or cyclic, saturated or unsaturated hydrocarbon group, or R?4 and R5¿ may form a hydrocarbon group together; and X represents (B). In formula (II), R11 represents a straight-chain or branched hydrocarbon group carrying 10 to 40 carbon atoms; R12 represents a straight-chain or branched hydrocarcon group carrying 1 to 39 carbon atoms; R13 represents a hydrogen atom or a hydrocarbon group carrying 1 to 6 carbon atoms; and R14 represents a hydrogen atom or a hydrocarbon group having a straight-chain, branched or cyclic structure and carrying 1 to 40 carbon atoms which may contain an oxygen atom.

公开(公告)号：EP1588819A4

公开(公告)日：2007-04-04

申请号：EP03758776

申请日：2003-10-22

Applicant: KAO CORP

Inventor： ODAJIMA SHINGO ,  ISSHIKI NOBUYUKI ,  OGA HIDETOSHI ,  OTSUKA HITOSHI ,  GOTO MINORU ,  KAWAMATA AKIRA

IPC: C08L91/06 ,  C08L7/00 ,  C08L9/00 ,  C08L9/02 ,  C08L19/00 ,  C08L91/08

CPC classification number: C08L91/08 ,  C08L7/00 ,  C08L9/00 ,  C08L9/02 ,  C08L19/00 ,  C08L91/06 ,  Y10T428/31801 ,  C08L2666/04

Abstract: A method for producing a composition containing a wax as its primary component, characterized in that it comprises admixing said wax and a material to be mixed with said wax through applying an external force at a temperature at which the melting of said wax is not completed.

公开(公告)号：EP0691327A4

公开(公告)日：1996-05-01

申请号：EP94910037

申请日：1994-03-17

Applicant: KAO CORP

Inventor： OHASHI YUKIHIRO ,  YADA YUKIHIRO ,  TAKEMA YOSHINORI ,  FUJIMORI TAKETOSHI ,  KAWAMATA AKIRA ,  OSU HIROYUKI ,  HIGUCHI KAZUHIKO ,  IMOKAWA GENJI ,  KUSUOKU HIROSHI ,  OGAWA AYUMI ,  FUJIMURA TSUTOMU

IPC: A61K8/41 ,  A61K8/46 ,  A61K8/49 ,  A61K8/68 ,  A61K31/13 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/08 ,  C07C215/08 ,  C07C215/10 ,  C07C215/12 ,  C07C217/28 ,  C07C219/06 ,  C07C229/12 ,  C07C229/24 ,  C07C233/18 ,  C07C235/10 ,  C07C237/06 ,  C07C323/25 ,  C07D295/088 ,  C07D311/58 ,  C07D311/72 ,  C07D317/22 ,  C07F7/08 ,  C07F9/09 ,  C07H15/04 ,  A61K7/48

CPC classification number: C07C323/25 ,  A61K8/41 ,  A61K8/46 ,  A61K8/49 ,  A61K8/68 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/08 ,  C07C215/08 ,  C07C215/10 ,  C07C215/12 ,  C07C217/28 ,  C07C219/06 ,  C07C229/12 ,  C07C229/24 ,  C07C233/18 ,  C07C235/10 ,  C07D295/088 ,  C07D311/58 ,  C07D311/72 ,  C07D317/22 ,  C07F7/0818 ,  C07F7/0847 ,  C07F7/0852 ,  C07F9/091 ,  C07H15/04 ,  Y10S514/844 ,  Y10S514/845 ,  Y10S514/873

Abstract: An amine derivative of following general formula (I) or (II) (wherein R1 represents a heteroatom-containing C¿1?-C40 hydrocarbon group which may have a ring structure, etc.; R?2 to R6¿ each represent a C¿1?-C10 hydrocarbon group, hydrogen, etc.; A?1¿ represents (i) or R?15-Z-R16(CH¿2)n-; B1 represents hydrogen, a C¿1?-C10 hydrocarbon group, nitrogen, etc.; and C?1¿ represents hydrogen, a C¿1?-C10 hydrocarbon group, nitrogen, alcohol residue, phosphoric acid residue, etc.); a dermatologic preparation containing the same; and a process for producing the amine derivative. The amine derivative has excellent effects of smoothing wrinkles and improving keratodermia.

公开(公告)号：EP0640644A4

公开(公告)日：1994-11-09

申请号：EP93904340

申请日：1993-02-23

Applicant: KAO CORP

Inventor： OKADA JOJI ,  KAWAMATA AKIRA ,  TOKUNAGA TADAYUKI ,  NAGATANI NOBORU ,  TORIZUKA MAKOTO ,  ASAHI MASAHIKO

IPC: A61K8/03 ,  A61K8/58 ,  A61K8/70 ,  A61K8/894 ,  A61K8/897 ,  A61K8/898 ,  A61Q1/02 ,  A61Q1/08 ,  A61Q1/10 ,  A61Q1/12 ,  A61Q3/00 ,  A61Q17/04 ,  A61Q19/00 ,  C08G77/14 ,  C08G77/24 ,  C08G77/385 ,  C08G77/46 ,  C08J3/03 ,  C08L83/06 ,  A61K7/02

CPC classification number: C08G77/385 ,  A61K8/03 ,  A61K8/585 ,  A61K8/70 ,  A61K8/894 ,  A61K8/897 ,  A61Q1/02 ,  A61Q1/08 ,  A61Q1/10 ,  A61Q1/12 ,  A61Q17/005 ,  A61Q17/04 ,  A61Q19/00

Abstract: A fluorine-modified polysiloxane derivative having an organopolysiloxane chain partially replaced by a siloxane chain represented by general formula (1), (2), (3), a process for the production thereof, an intermediate to be used for the production thereof, and a cosmetic containing the same, wherein Rf and Rf' represent each C1-C20 perfluoroalkyl or omega -H-perfluoroalkyl of the formula H(CF2)t- wherein t represents an integer of 1 to 20; a number of R groups may be the same or different from each other and each represents C1-C20 linear or branched aliphatic hydrocarbyl or C5-C10 cycloaliphatic or aromatic hydrocarbyl; R represents hydrogen, C1-C20 linear or branched aliphatic hydrocarbyl, C5-C10 cycloaliphatic or aromatic hydrocarbyl, C1-C20 perfluoroalkyl or omega -H-perfluoroalkyl of the formula H(CF2)u- wherein u represents an integer of 1 to 20; R represents a C2-C10 divalent hydrocarbon group; X and Y represent each a single bond, -CO- or a C1-C6 divalent hydrocarbon group; l represents a number of 2 to 16; m and n represent each a number of 1 to 6; and r represents a number of 0 to 50. A cosmetic containing this compound has excellent water and oil repellency, can be held on the skin for long, and is comfortable to use.

公开(公告)号：EP1495751A4

公开(公告)日：2005-09-14

申请号：EP02720492

申请日：2002-04-18

Applicant: KAO CORP

Inventor： ABE HIDEYUKI ,  KAWAMATA AKIRA ,  KIYOMINE AKIRA

IPC: A61K8/00 ,  A61K8/22 ,  A61K8/41 ,  A61K8/44 ,  A61K8/49 ,  A61Q5/08 ,  A61Q5/10 ,  A61K7/13 ,  C11D3/395 ,  D06P3/08

CPC classification number: A61Q5/08 ,  A61K8/22 ,  A61K8/44 ,  A61K8/494 ,  A61K8/4966 ,  A61Q5/10

Abstract: A hairdye composition which comprises a mixture of a first ingredient comprising an alkali agent and a second ingredient comprising an oxidizing agent, the first and second ingredients being mixed at time of use. The mixture comprises (a) a triazacyclononane compound (1) or a salt thereof, (b) an oxidizing agent in an amount of 0.1 to 12 wt.% in terms of hydrogen peroxide, and (c) 0.05 to 10 wt.% alkali agent, and has a pH of 7.5 to 12. (1) (2) [R to R each is hydrogen or C1-6 alkyl optionally substituted by OH, and R to R each is hydrogen, (substituted) C1-6 alkyl, (substituted) aralkyl, (substituted) heteroarylalkyl, (substituted) aryl, (substituted) heteroaryl, (substituted) C1-6 acyl, or a group represented by (2) (R to R each is hydrogen, C1-6 alkyl, aralkyl, or aryl and n is a number of 2 to 30).] The hairdye composition has an excellent decoloring ability and can dye the hair in a bright satisfactory tone. It is less apt to damage the hair or irritate the head skin.

Abstract translation: 一种染发剂组合物，其包含含有碱性剂的第一成分和含有氧化剂的第二成分的混合物，第一和第二成分在使用时混合。 该混合物含有（a）三氮杂环壬烷化合物（1）或其盐，（b）以过氧化氢换算为0.1〜12重量％的氧化剂，和（c）0.05〜10重量％碱 （1）（2）[R 1至R 4各自为氢或任选被OH取代的C 1-6烷基，且R 5至R 7各自独立地为氢， （取代）C1-6烷基，（取代）芳烷基，（取代）杂芳基烷基，（取代）芳基，（取代）杂芳基，（取代）C1-6酰基或（2） 8至R 12各自为氢，C 1-6烷基，芳烷基或芳基，并且n为2至30的数）。]所述染发剂组合物具有优异的脱色能力并且能够以良好的光泽 音。 它不太容易损伤头发或刺激头部皮肤。

公开(公告)号：EP0755671A4

公开(公告)日：1997-04-09

申请号：EP95914561

申请日：1995-04-11

Applicant: KAO CORP

Inventor： YAMAGUCHI MASAKAZU ,  KAWAMATA AKIRA ,  OHSU HIROYUKI ,  TAKEMA YOSHINORI ,  IMOKAWA GENJI

IPC: A61K8/49 ,  A61Q17/04 ,  A61K7/48 ,  A61K7/00

CPC classification number: A61Q17/04 ,  A61K8/4973 ,  A61Q19/08

Abstract: A dermatologic preparation containing a furan derivative represented by general formula (1) as the active ingredient, wherein X represents optionally substituted furan, benzofuran or isobenzofuran residue; and R and R represent each C1-C8 linear, branched or cyclic alkyl which may be substituted by X-CH2-N(R )- (wherein R represents C1-C6 linear or branched alkyl; and X is as defined above), or R and R together with the adjacent nitrogen atom may form a heterocycle which may be substituted by X-CH2- (wherein X is as defined above). The preparation is excellent in the effect of inhibiting wrinkling due to exposure to ultraviolet radiations, especially UV-B, and hence useful for the inhibition of wrinkling.

公开(公告)号：MY129994A

公开(公告)日：2007-05-31

申请号：MYPI9101536

申请日：1991-08-23

Applicant: KAO CORP

Inventor： SHIOYA YASUSHI ,  SUZUKI YUJI ,  TAKEUCHI KEN ,  YOSHINO KOJI ,  KAWAMATA AKIRA

IPC: C07F7/04 ,  A61K8/893 ,  A61K8/896 ,  A61K47/24 ,  A61Q1/00 ,  A61Q1/02 ,  A61Q5/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/10 ,  C07F7/08 ,  C08G77/38

Abstract: NOVEL SILOXANE DERIVATIVES REPRESENTED BY GENERAL FORMULA (I)(FORMULA 1)A METHOD FOR PRODUCING THE SILOXANE DERIVATIVES AND AGENTS SUCH AS COSMETIC PREPARATION, EMULSIFYING DERMATOTHERAPEUTIC EXTERNAL AGENTS AND THE LIKE INCLUDING AT LEAST ONE OF THE SILOXANE DERIVATIVES ARE ALSO DISCLOSED.

公开(公告)号：DE69128321T2

公开(公告)日：1998-05-20

申请号：DE69128321

申请日：1991-08-19

Applicant: KAO CORP

Inventor： SHIOYA YASUSHI ,  SUZUKI YUJI ,  TAKEUCHI KEN ,  YOSHINO KOJI ,  KAWAMATA AKIRA

IPC: A61K8/893 ,  A61K8/896 ,  A61K47/24 ,  A61Q1/00 ,  A61Q1/02 ,  A61Q5/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/10 ,  C07F7/08 ,  C08G77/38 ,  A61K7/00

Abstract: Novel siloxane derivatives represented by general formula (1): A method for producing the siloxane derivatives and agents such as cosmetic preparations, emulsifying dermatotherapeutic external agents and the like including at least one of the siloxane derivatives are also disclosed.

公开(公告)号：DE69128321D1

公开(公告)日：1998-01-15

申请号：DE69128321

申请日：1991-08-19

Applicant: KAO CORP

Inventor： SHIOYA YASUSHI ,  SUZUKI YUJI ,  TAKEUCHI KEN ,  YOSHINO KOJI ,  KAWAMATA AKIRA

IPC: A61K8/893 ,  A61K8/896 ,  A61K47/24 ,  A61Q1/00 ,  A61Q1/02 ,  A61Q5/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/10 ,  C07F7/08 ,  C08G77/38 ,  A61K7/00

Abstract: Novel siloxane derivatives represented by general formula (1): A method for producing the siloxane derivatives and agents such as cosmetic preparations, emulsifying dermatotherapeutic external agents and the like including at least one of the siloxane derivatives are also disclosed.

公开(公告)号：DE69110507D1

公开(公告)日：1995-07-27

申请号：DE69110507

申请日：1991-03-15

Applicant: KAO CORP

Inventor： OHASHI YUKIHIRO ,  TAKEUCHI KEN ,  SUDA MITUO ,  YOSHINO KOJI ,  KAWAMATA AKIRA ,  MASTUI YOKO ,  SUZUKI YUJI

IPC: A61K8/72 ,  A61K8/00 ,  A61K8/89 ,  A61K8/894 ,  A61K8/898 ,  A61Q1/00 ,  A61Q1/02 ,  A61Q1/04 ,  A61Q1/08 ,  A61Q1/12 ,  A61Q19/00 ,  C08G77/38 ,  C08G77/46 ,  C08L83/12 ,  A61K7/00

Abstract: An ester-modified silicone derivative of formula (I): wherein R and R are the same or different and each represents a saturated or unsaturated straight- or branched-chain aliphatic hydrocarbon group having from 2 to 30 carbon atoms, a saturated or unsaturated alicyclic hydrocarbon group having from 3 to 30 carbon atoms or an aromatic hydrocarbon groups having from 6 to 30 carbon atoms; l and m each represents a number of 0 to 100; n represents a number of 1 to 100; a represents a number of 3 to 16; and b represents a number of 1 to 3 is disclosed as well as a cosmetic composition containing the ester-modified silicone derivative.