公开(公告)号：DE10235914A1

公开(公告)日：2004-02-19

申请号：DE10235914

申请日：2002-08-06

Applicant: LEICA MICROSYSTEMS

Inventor： MOELLMANN KYRA

IPC: G01N21/63 ,  G02B21/00 ,  G02B21/06 ,  G02F1/35 ,  G02F1/37

Abstract: The light source (10) has 2 lasers (4,6), e.g. 2 synchronized short pulse lasers, providing respective light beams, which are fed to an optical combining device (24), inserted in each beam path (4a,6a), with an adjustable deflection device (22) positioned in one beam path ahead of the optical combining device, for determining the wavelength difference between the 2 light beams. An Independent claim for a scanning microscope system is also included.

公开(公告)号：DE102004030208B3

公开(公告)日：2005-12-15

申请号：DE102004030208

申请日：2004-06-22

Applicant: LEICA MICROSYSTEMS

Inventor： HOFFMANN JUERGEN ,  KNEBEL WERNER ,  MOELLMANN KYRA

IPC: G02B21/00 ,  G02B21/06

Abstract: An optical device comprising an acousto-optical component is arranged in the illumination beam path and in the observation beam path. A splitter/combiner splits/combines the illumination beam path and the observation beam path. An independent claim is included for an optical device.

公开(公告)号：DE102004011770A1

公开(公告)日：2005-10-13

申请号：DE102004011770

申请日：2004-03-09

Applicant: LEICA MICROSYSTEMS

Inventor： MOELLMANN KYRA ,  HOFFMANN JUERGEN

IPC: G02B21/00 ,  G02B21/06

Abstract: Scanning microscope comprises a beam deflection device (1) that deflects a first illuminating light beam (5) to scan a sample (13), and a second beam deflection device (33) that deflects a second illuminating light beam (37). The first and the second beam deflection device deflect the second illuminating light beam. An independent claim is also included for a module comprising a second beam deflection device for coupling to a scanning microscope with a first beam deflection device. Preferred Features: The first and the second beam deflection devices are synchronized with each other.

公开(公告)号：DE10252005B4

公开(公告)日：2005-06-16

申请号：DE10252005

申请日：2002-11-06

Applicant: LEICA MICROSYSTEMS

Inventor： MOELLMANN KYRA

IPC: G02B21/00 ,  G02B21/16 ,  H01S3/06 ,  H01S3/091 ,  H01S3/094 ,  G02F1/00

公开(公告)号：DE10337296A1

公开(公告)日：2005-03-03

申请号：DE10337296

申请日：2003-08-14

Applicant: LEICA MICROSYSTEMS

Inventor： KNEBEL WERNER ,  MOELLMANN KYRA

IPC: G02B21/00 ,  G02B21/06

Abstract: Scanning microscope has a light source which generates an illumination light beam for illumination of a sample, with means for spectrally splitting and at least partially screening the detection light emitted by the sample. The illuminating light beam travels through the spectral splitting and screening means.

公开(公告)号：DE10331906A1

公开(公告)日：2005-02-17

申请号：DE10331906

申请日：2003-07-15

Applicant: LEICA MICROSYSTEMS

Inventor： MOELLMANN KYRA

IPC: G02B6/42 ,  G02B21/00 ,  G02B21/06 ,  G02B6/02

Abstract: A light source with a microstructured optical element which spectrally diffuses the light from a primary source, comprises a lens which focusses the spectrally-diffused light to give an illumination light beam. The lens compensates for the varying divergences of the spectral components of the spectrally diffused light. The invention further relates to a microscope.

公开(公告)号：DE10313138A1

公开(公告)日：2004-10-21

申请号：DE10313138

申请日：2003-03-24

Applicant: LEICA MICROSYSTEMS

Inventor： SCHREIBER FRANK ,  MOELLMANN KYRA

IPC: G01N21/64 ,  G02B21/00 ,  G02B21/08 ,  G02B21/18

Abstract: The object (1) is excited into emission, and emitted light (13) reaches a detector (15) via a main beam splitter (9) and a detection beam path (16). The main beam splitter is a switchable beam splitter, preferably an acousto-optical beam splitter. The stimulation light is within the fluorescence spectrum.

公开(公告)号：DE10142229A1

公开(公告)日：2003-04-03

申请号：DE10142229

申请日：2001-08-29

Applicant: LEICA MICROSYSTEMS

Inventor： ENGELHARDT JOHANN ,  MOELLMANN KYRA

IPC: G02B21/24

Abstract: A microscope includes a lens holder for receiving a lens. A locking device is provided that affixes the received lens so that the lens cannot be removed without authorization.

公开(公告)号：DE502004008546D1

公开(公告)日：2009-01-08

申请号：DE502004008546

申请日：2004-09-23

Applicant: LEICA MICROSYSTEMS

Inventor： ULRICH HEINRICH ,  KNEBEL WERNER ,  MOELLMANN KYRA

IPC: G02B21/00 ,  G02B21/02 ,  G02B21/06 ,  G02B21/08 ,  G02B21/32

Abstract: A scanning microscope includes a light source for evanescently illuminating a sample disposed on a slide. A point detector receives detection light emanating from a scanning point of the sample. A beam deflection device disposed in an optical path of the detection light can shift a position of the scanning point.

公开(公告)号：DE10251345B4

公开(公告)日：2006-08-17

申请号：DE10251345

申请日：2002-11-05

Applicant: LEICA MICROSYSTEMS

Inventor： HOPPE MARTIN ,  KNEBEL WERNER ,  MOELLMANN KYRA ,  STORZ RAFAEL

IPC: A61B5/00 ,  A61B5/02 ,  G02B21/24

Abstract: The invention concerns a method and an apparatus for investigating layers ( 1 ) of tissues in living animals using a microscope ( 2 ). The microscope ( 2 ) is focused onto a layer ( 1 ), and images of the layer ( 1 ) are acquired or optical measurements are performed on it. Positional changes of the layer ( 1 ) are brought about by movements of the animal or of its organs. The positional changes are sensed, and corresponding signals are generated. The signals are stored, together with the corresponding images or measurement results, for later evaluation; or they are processed in such a way that the positional changes are compensated for in order to investigate the layer ( 1 ). As a result, the layer ( 1 ) can be qualitatively or quantitatively investigated microscopically, irrespective of the movement of the animal or its organs.