-
1.发明专利
公开(公告)号：JP2002131649A
公开(公告)日：2002-05-09
申请号：JP2001236488
申请日：2001-08-03
Applicant: LEICA MICROSYSTEMS
Inventor： ENGELHARDT JOHANN , HOFFMANN JUERGEN
Abstract: PROBLEM TO BE SOLVED: To provide a scanning microscope which has a light source (1) preferably being a laser for generating an irradiation light beam (14) for a sample (11) and a scanner for deflecting the irradiation light beam (14) and realizes image data acquisition of a high speed and high reliability and a compact structure, more preferably a confocal scanning microscope and further to provide a scanning microscope method utilizing the light source (1) preferably being the laser for generating the irradiation light beam (14) for the sample (11) and the scanner for deflecting the irradiation light beam (14), more particularly a method for image formation in the confocal scanning microscope method. SOLUTION: The scanner is improved by constituting the same in a manner as to have at least one micromirror (16). The at least one micromirror (16) is used in the range of the scanner.
-
公开(公告)号：JP2002107633A
公开(公告)日：2002-04-10
申请号：JP2001267466
申请日：2001-09-04
Applicant: LEICA MICROSYSTEMS
Inventor： ENGELHARDT JOHANN , HOFFMANN JUERGEN
Abstract: PROBLEM TO BE SOLVED: To provide a method and a device for optimizing or increasing the fluorescent light photon collection quantity of a fluorescent substance excited by multiple photon excitation so as to generate fluorescence in order to detect an optimum sample as to a method and a device for detecting fluorescence in a scanning microscopic method, especially a confocal scanning microscopic method. SOLUTION: The operation variable of a light source (2) generating multiple photon excitation and/or the system variable of a confocal scanning microscope is suited to the characteristics of a fluorescent material as to the optimum fluorescent photon collection quantity.
-
公开(公告)号：JP2012177923A
公开(公告)日：2012-09-13
申请号：JP2012064069
申请日：2012-03-21
Inventor： HOFFMANN JUERGEN
CPC classification number: G02B21/0056 , G02B21/0032 , G02B21/0068 , G02B21/0076
Abstract: PROBLEM TO BE SOLVED: To provide a sample irradiation device with a simple arrangement and capable of reducing the number of optical elements for each inductive beam path.SOLUTION: This invention, preferably used in a confocal fluorescence scanning type microscope method, is relate to a device irradiating sample (1) comprising: one irradiation beam path (2) of one light source (3) and at least another irradiation beam path (4) of another light source (5). In order to simplify arrangement in the irradiation beam path and to reduce the number of optical elements, at least one optical element (7) is placed at least one side of the irradiation beam paths (2), (4) so that the optical element (7) denaturalizes light.
Abstract translation: 要解决的问题：提供一种具有简单布置并能够减少每个感应束路径的光学元件数量的样品照射装置。 解决方案：优选以共焦荧光扫描型显微镜方法使用的本发明涉及一种照射样品（1）的装置，包括：一个光源（3）的一个照射束路径（2）和至少另一个照射 另一光源（5）的光束路径（4）。 为了简化照射光束路径中的布置并减少光学元件的数量，至少一个光学元件（7）被放置在照射光束路径（2），（4）的至少一侧，使得光学元件 （7）使光变质。 版权所有（C）2012，JPO＆INPIT
-
公开(公告)号：JP2002122786A
公开(公告)日：2002-04-26
申请号：JP2001185233
申请日：2001-06-19
Applicant: LEICA MICROSYSTEMS
Inventor： HOFFMANN JUERGEN
IPC: G02B21/00
Abstract: PROBLEM TO BE SOLVED: To remove a loss of exciting light or detection light in a main beam splitter, for a scanning microscopy and a confocal scanning microscope. SOLUTION: The scanning microscope (100) is provided with at least one light source (4), an objective lens (10) and at least one detector (12). A light circulator (14) is arranged between at least one light source (4), the objective lens (10) and at least one detector (12). In another embodiment, the scanning microscope (100) is constituted as a confocal microscope.
-
公开(公告)号：JP2001324679A
公开(公告)日：2001-11-22
申请号：JP2001100297
申请日：2001-03-30
Applicant: LEICA MICROSYSTEMS
Inventor： ENGELHARDT JOHANN , HOFFMANN JUERGEN , STORZ RAFAEL , ULRICH HEINRICH , BEWERSDORF JOERG , BIRK HOLGER
Abstract: PROBLEM TO BE SOLVED: To form a low output power laser beam source which can be utilized especially as a light source for a confocal scanning type microscopic method. SOLUTION: In this device for coupling beams from at least two laser beam sources 1 and 2 related to the confocal scanning type microscopic method, the beams from the laser beam sources 1 and 2 at least have nearly the same wavelength. The device is provided with at least a beam coupling device 11 coupling light beams by a system hardly having loss.
-
Patent Agency Ranking
公开(公告)号：JP2001356274A
公开(公告)日：2001-12-26
申请号：JP2001105913
申请日：2001-04-04
Applicant: LEICA MICROSYSTEMS
Inventor： ENGELHARDT JOHANN , BEWERSDORF JOERG , GUGEL HILMAR , HOFFMANN JUERGEN
Abstract: PROBLEM TO BE SOLVED: To provide a double confocal scanning type microscope which can realize at least almost theoretically realizable resolution especially in association with polychromatic fluorescent use. SOLUTION: This invention relates to the double confocal scanning type microscope having an irradiation beam passage 2 of at least one light source 3 and a detection beam passage 4 of at least one detector 5. In particular, optical characteristics of elements 6, 10, 13 and 14 arranged at the beam passages are mutually adjusted so that accumulated aberration is at least as large as theoretically realizable resolution as to an optical axis 33 and/or at least one surfaces 18, 19 and 20 of a sample region.
-
公开(公告)号：JP2001290081A
公开(公告)日：2001-10-19
申请号：JP2001070538
申请日：2001-03-13
Applicant: LEICA MICROSYSTEMS
Inventor： HOFFMANN JUERGEN
Abstract: PROBLEM TO BE SOLVED: To provide a sample irradiation equipment with a simple arrangement and having the reduced number of optical elements for each inductive beam route. SOLUTION: The sample irradiation equipment preferably used in a confocal fluorescence scanning type microscopy has one irradiation beam route (2) of one light source (3) and at least one another irradiation beam route (4) of another light source (5) and applies irradiation to a sample (1). In order to simplify an arrangement in the irradiation beam route and to reduce the number of optical elements, at least one optical element (7) is placed at least one side of the irradiation beam route (2, 4) so that an optical element (7) denaturalizes a beam.
-
公开(公告)号：DE102005027077A1
公开(公告)日：2006-05-11
申请号：DE102005027077
申请日：2005-06-11
Applicant: LEICA MICROSYSTEMS
Inventor： KNEBEL WERNER , HOFFMANN JUERGEN
Abstract: Microscope has an illumination unit (3) producing light beams to illuminate a sample in an illuminating plane lying at an angle different from 90[deg] to the detection unit (29). Preferred Features: The illumination plane lies at an angle of less than 80[deg] or more than 100[deg] to the detection unit. The illumination plane rotates relative to the sample, preferably about an axis of rotation aligned in the detection unit. The illumination unit contains an adjustable beam deviating unit.
-
公开(公告)号：DE102004030208B3
公开(公告)日：2005-12-15
申请号：DE102004030208
申请日：2004-06-22
Applicant: LEICA MICROSYSTEMS
Inventor： HOFFMANN JUERGEN , KNEBEL WERNER , MOELLMANN KYRA
Abstract: An optical device comprising an acousto-optical component is arranged in the illumination beam path and in the observation beam path. A splitter/combiner splits/combines the illumination beam path and the observation beam path. An independent claim is included for an optical device.
-
公开(公告)号：DE102004011770A1
公开(公告)日：2005-10-13
申请号：DE102004011770
申请日：2004-03-09
Applicant: LEICA MICROSYSTEMS
Inventor： MOELLMANN KYRA , HOFFMANN JUERGEN
Abstract: Scanning microscope comprises a beam deflection device (1) that deflects a first illuminating light beam (5) to scan a sample (13), and a second beam deflection device (33) that deflects a second illuminating light beam (37). The first and the second beam deflection device deflect the second illuminating light beam. An independent claim is also included for a module comprising a second beam deflection device for coupling to a scanning microscope with a first beam deflection device. Preferred Features: The first and the second beam deflection devices are synchronized with each other.
-
-
-
-
-
-
-
-
-
Search Results
70
records
(took 0.035 seconds)
