-
公开(公告)号：WO2004091502A8
公开(公告)日：2005-11-24
申请号：PCT/US2004011106
申请日：2004-04-09
Applicant: PTC THERAPEUTICS INC , KARP GARY MITCHELL , HWANG SEONGWOO , CHEN GUANGMING , ALMSTEAD NEIL GREGORY
Inventor： KARP GARY MITCHELL , HWANG SEONGWOO , CHEN GUANGMING , ALMSTEAD NEIL GREGORY
IPC: A61K31/4245 , C07D271/06 , C07D271/12 , C07D413/04 , C07D413/10
CPC classification number: A61K31/4245 , A61K9/0053 , A61K9/12 , A61K9/48 , A61K31/4439 , A61K31/454 , A61K31/4545 , A61K31/5377 , A61K31/655 , A61K45/06 , C07D271/06 , C07D271/12 , C07D285/14 , C07D413/02 , C07D413/04 , C07D413/10
Abstract: Novel 1,2,4-oxadiazole benzoic acid compounds, methods of using and pharmaceutical compositions comprising an 1,2,4-oxadiazole benzoic acid derivative are disclosed. The methods include methods of treating or preventing a disease ameliorated by modulation of premature translation termination or nonsense-mediated mRNA decay, or ameliorating one or more symptoms associated therewith.
Abstract translation: 公开了新的1,2,4-恶二唑苯甲酸化合物，使用方法和包含1,2,4-恶二唑苯甲酸衍生物的药物组合物。 所述方法包括治疗或预防通过调节过早翻译终止或无义介导的mRNA衰变而改善的疾病或改善与其相关的一种或多种症状的方法。
-
12.发明申请UREIDO SUBSTITUTED BENZOIC ACID COMPOUNDS, THEIR USE FOR NONSENSE SUPPRESSION AND THE TREATMENT OF DISEASES CAUSED BY SUCH MUTATIONS 审中-公开UREIDO替代苯甲酸化合物，其用于非抑制和治疗由这些突变引起的疾病
公开(公告)号：WO2004009558A3
公开(公告)日：2004-04-15
申请号：PCT/US0323182
申请日：2003-07-23
Applicant: PTC THERAPEUTICS INC , WILDE RICHARD G , TAKASUGI JAMES J , HWANG SEONGWOO , WELCH ELLEN M , CHEN GUANGMING
Inventor： WILDE RICHARD G , TAKASUGI JAMES J , HWANG SEONGWOO , WELCH ELLEN M , CHEN GUANGMING
IPC: A61K31/17 , A61K31/4166 , A61P35/00 , C07C275/42 , C07D233/32 , C07D233/42 , C07D233/70 , C07D233/72 , C07D233/78 , C07D233/84 , C07D285/16 , C07D401/04 , C07D401/10 , C07D405/04 , C07D405/06 , C07D409/04 , C07D285/06 , C07D403/10 , C07D409/10
CPC classification number: C07D285/16 , A61K31/17 , A61K31/4166 , A61K31/4172 , A61K31/4196 , A61K31/421 , A61K31/426 , C07C275/42 , C07D233/32 , C07D233/42 , C07D233/72 , C07D401/04 , C07D401/10 , C07D405/04 , C07D405/06 , C07D409/04
Abstract: The invention encompasses ureido substituted benzoic acid compounds of structure (I), compositions comprising the compounds and methods for treating or preventing diseases associated with nonsense mutations of mRNA by administering these compounds or compositions.
Abstract translation: 本发明包括结构式（I）的脲基取代的苯甲酸化合物，包含该化合物的组合物以及通过施用这些化合物或组合物来治疗或预防与无义突变相关的疾病的方法。
-
13.发明公开SUBSTITUTED PYRIDINE AND PYRAZINE BMI-1 INHIBITORS 审中-公开SUBSTITUIERTE PYRIDIN- UND PRARAZIN-BMI-1-HEMMER
公开(公告)号：EP3071553A4
公开(公告)日：2017-08-02
申请号：EP13897883
申请日：2013-11-21
Applicant: PTC THERAPEUTICS INC
Inventor： BAIAZITOV RAMIL , CHOI SOONGYU , DU WU , HWANG SEONGWOO , LEE CHANG-SUN , LIU RONGGANG , MOON YOUNG-CHOON , PAGET STEVEN D , REN HONGYU , SYDORENKO NADIYA , WILDE RICHARD GERALD
IPC: C07D241/20 , A61K31/497 , A61K45/06 , C07D401/04 , C07D401/14 , C07D403/14 , C07D405/14 , C07D413/04 , C07D417/14 , C07D471/04 , C07D487/04 , C07D513/04
CPC classification number: C07D403/04 , A61K31/497 , A61K31/4985 , A61K31/519 , A61K31/69 , A61K45/06 , C07D401/04 , C07D401/14 , C07D403/14 , C07D405/14 , C07D413/04 , C07D417/14 , C07D471/04 , C07D487/04 , C07D513/04 , C07F5/04
-
公开(公告)号：MX391850B
公开(公告)日：2025-03-19
申请号：MX2021001091
申请日：2018-06-08
Applicant: PTC THERAPEUTICS INC
Inventor： BHATTACHARYYA ANURADHA , JANI MINAKSHI , SYDORENKO NADIYA , HWANG SEONGWOO , BABU SURESH , MOON YOUNG-CHOON
IPC: C07D237/20 , C07D401/14 , C07D403/12 , C07D405/12 , C07D413/14 , C07D417/04 , C07D417/14 , C07D471/10 , C07D487/10
Abstract: La presente descripción se relaciona con compuestos, formas, y composiciones farmacéuticas de los mismos y los métodos para utilizar estos compuestos, formas, o composiciones de los mismos para tratar o mejorar la enfermedad de Huntington. En particular, la presente descripción se relaciona con compuestos de heteroarilo monocíclico sustituido de la Fórmula (I), las formas y composiciones farmacéuticas de los mismos y los métodos para utilizar estos compuestos, formas, o composiciones de los mismos para tratar o mejorar la enfermedad de Huntington.
-
公开(公告)号：MX382671B
公开(公告)日：2025-03-13
申请号：MX2018007022
申请日：2018-06-08
Applicant: PTC THERAPEUTICS INC
Inventor： BHATTACHARYYA ANURADHA , JANI MINAKSHI , SYDORENKO NADIYA , HWANG SEONGWOO , BABU SURESH , MOON YOUNG- CHOON
IPC: A61K31/506 , A61K33/00 , A61P25/00 , C07D201/00 , C07D237/20 , C07D401/14 , C07D403/12 , C07D405/12 , C07D413/14 , C07D417/04 , C07D417/14 , C07D471/10 , C07D487/10
Abstract: La presente descripción se relaciona con compuestos, formas, y composiciones farmacéuticas de los mismos y los métodos para utilizar ESTOS compuestos, formas, o composiciones de los mismos para tratar o mejorar la enfermedad de Huntington. En particular, la presente descripción se relaciona con compuestos de heteroarilo monocíclico sustituido de la Fórmula (I), las formas y composiciones farmacéuticas de los mismos y los métodos para utilizar estos compuestos, formas, o composiciones de los mismos para tratar o mejorar la enfermedad de Huntington.
-
Patent Agency Ranking
公开(公告)号：PL3386511T3
公开(公告)日：2021-11-08
申请号：PL16874024
申请日：2016-12-11
Applicant: PTC THERAPEUTICS INC
Inventor： BABU SURESH , BHATTACHARYYA ANURADHA , HWANG SEONGWOO , JANI MINAKSHI , MOON YOUNG-CHOON , SYDORENKO NADIYA
IPC: A61K31/501 , C07D403/12 , A61K31/506 , A61K31/517 , C07D237/20 , C07D401/14 , C07D403/10 , C07D405/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/10 , C07D487/10
-
公开(公告)号：SI3386511T1
公开(公告)日：2021-09-30
申请号：SI201631243
申请日：2016-12-11
Applicant: PTC THERAPEUTICS INC
Inventor： BABU SURESH , BHATTACHARYYA ANURADHA , HWANG SEONGWOO , JANI MINAKSHI , MOON YOUNG-CHOON , SYDORENKO NADIYA
IPC: C07D403/00 , A61K31/00 , C07D237/00 , C07D401/00 , C07D405/00 , C07D413/00 , C07D417/00 , C07D471/00 , C07D487/00
-
公开(公告)号：AU2020201380B2
公开(公告)日：2020-10-08
申请号：AU2020201380
申请日：2020-02-25
Applicant: PTC THERAPEUTICS INC
Inventor： BABU SURESH , BHATTACHARYYA ANURADHA , HWANG SEONGWOO , JANI MINAKSHI , MOON YOUNG-CHOON , SYDORENKO NADIYA
IPC: C07D405/12 , A61K31/506 , A61P25/00
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. N-N (I) In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
-
公开(公告)号：PL3345895T3
公开(公告)日：2020-05-18
申请号：PL17204895
申请日：2004-04-09
Applicant: PTC THERAPEUTICS INC
Inventor： KARP GARY MITCHELL , HWANG SEONGWOO , CHEN GUANGMING , ALMSTEAD NEIL GREGORY , MOON YOUNG-CHOON
IPC: C07D271/06 , A61K31/4245 , A61P27/02 , A61P35/00 , C07D271/12 , C07D413/04 , C07D413/10
-
公开(公告)号：HUE047569T2
公开(公告)日：2020-04-28
申请号：HUE17204895
申请日：2004-04-09
Applicant: PTC THERAPEUTICS INC
Inventor： KARP GARY , HWANG SEONGWOO , CHEN GUANGMING , ALMSTEAD NEIL GREGORY , MOON YOUNG-CHOON
IPC: A61K31/4245 , A61P27/02 , A61P35/00 , C07D271/06 , C07D271/12 , C07D413/04 , C07D413/10
-
-
-
-
-
-
-
-
-
Search Results
121
records
(took 0.023 seconds)
