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11.发明申请METHODS AND SYSTEMS FOR DOSING AND COATING INHALATION POWDERS ONTO CARRIER PARTICLES 审中-公开用于给载体吸入粉末并将载体吸入载体颗粒的方法和系统
公开(公告)号：WO2011031564A3
公开(公告)日：2011-07-14
申请号：PCT/US2010047043
申请日：2010-08-27
Applicant: STC UNM , SMYTH HUGH D C , DONOVAN MARTIN J
Inventor： SMYTH HUGH D C , DONOVAN MARTIN J
CPC classification number: A61K9/0075 , A61K9/14 , A61K31/58
Abstract: A method of method of coating powdered medical agent onto a carrier particle for use in a dry powder inhaler may include applying ultrasonic energy to agglomerated powdered medical agent to deaggregate and aerosolize particles of the medical agent into particles having a desired average particle size, and coating at least one carrier particle with a desired amount of the deaggregated and aerosolized particles of the medical agent.
Abstract translation: 将粉末状药剂涂覆到用于干粉吸入器的载体颗粒上的方法可包括将超声波能量应用于聚集粉末药剂以将药剂颗粒解聚并雾化成具有期望平均粒度的颗粒， 至少一种载体颗粒与期望量的药物的解聚和雾化颗粒。
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公开(公告)号：CA2789674A1
公开(公告)日：2011-09-15
申请号：CA2789674
申请日：2011-03-09
Applicant: STC UNM
Inventor： SELVAM PARTHIBAN , SMYTH HUGH D C , DONOVAN MARTIN
Abstract: A device for coating dry powder microparticles onto a surfacemay include a jet mill configured to mill dry powder particles into microparticles having a desired aerodynamic diameter and to deaggregate the microparticles, a feed hopper structured and arranged to feed dry powder particles to the jet mill, a surface configured to receive dry powder microparticles and an exit nozzle associated with the jet mill. The exit nozzle may be arranged to direct deaggregated micronized dry powder particles from the jet mill to the surface to be coated. The device may further include a holder structured and arranged to hold an item, wherein the item includes the surface. In some aspects of the device, the item may be a film.
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公开(公告)号：CA2732585A1
公开(公告)日：2010-02-04
申请号：CA2732585
申请日：2009-07-30
Applicant: STC UNM
Inventor： SMYTH HUGH D C , DONOVAN MARTIN
IPC: A61K9/14
Abstract: A dry powder inhaler may include a drug chamber configured to contain a formulation including carrier particles and working agent particles, a mouthpiece configured to direct flow of working agent particles to a user, and a retaining member proximal the mouthpiece. The retaining member be sized and arranged to prevent flow of substantially all carrier particles to the user while permitting flow of working agent particles to a user. The inhaler may include a formulation including carrier particles for delivering working agent to the pulmonary system of a patient. The carrier particles may have an average sieve diameter greater than about 500 µm. The carrier particles may be one of polystyrene, PTFE, silicone glass, and silica gel or glass.
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公开(公告)号：AU2009276498A1
公开(公告)日：2010-02-04
申请号：AU2009276498
申请日：2009-07-30
Applicant: STC UNM
Inventor： SMYTH HUGH D C , DONOVAN MARTIN
IPC: A61K9/14
Abstract: A dry powder inhaler may include a drug chamber configured to contain a formulation including carrier particles and working agent particles, a mouthpiece configured to direct flow of working agent particles to a user, and a retaining member proximal the mouthpiece. The retaining member be sized and arranged to prevent flow of substantially all carrier particles to the user while permitting flow of working agent particles to a user. The inhaler may include a formulation including carrier particles for delivering working agent to the pulmonary system of a patient. The carrier particles may have an average sieve diameter greater than about 500 μm. The carrier particles may be one of polystyrene, PTFE, silicone glass, and silica gel or glass.
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