公开(公告)号：AU3733800A

公开(公告)日：2000-09-28

申请号：AU3733800

申请日：2000-03-08

Applicant: SYMYX TECHNOLOGIES INC

Inventor： KLAERNER GERRIT ,  SAFIR ADAM ,  NIELSEN RALPH B ,  JANDELEIT BERND ,  HUEFNER PETER ,  LI YUNXIAO

IPC: C08F2/22 ,  C08F2/28 ,  C08F2/38 ,  C08F4/00 ,  C08F220/58 ,  G01N33/543

Abstract: Nitroxides having an alpha-carbon atom with a destabilizing moiety are effective control agents for emulsion and water-based polymerizations, including the formation of block copolymers from a wide range of monomers. The nitroxide radicals may be used as a free radical or as an adduct with a residue from the initiator. The emulsions have living characteristics, including the re-initiation of polymer chains. Also, a seeded process for emulsions, which includes the step-wise addition of monomer is disclosed, providing access to a wide range of initiator types.

公开(公告)号：DE60027309T2

公开(公告)日：2006-08-31

申请号：DE60027309

申请日：2000-07-03

Applicant: SYMYX TECHNOLOGIES INC

Inventor： KLAERNER GERRIT ,  NIELSEN B ,  MANSKY PAUL ,  BENOIT DIDIER ,  CHARMOT DOMINIQUE ,  JANDELEIT BERND ,  MAZZOLA T

IPC: C08F292/00 ,  C08F4/00 ,  C08F220/54 ,  C08F220/58 ,  C12Q1/68 ,  G01N27/447 ,  G01N33/48 ,  G01N33/543

Abstract: Sensors for determining the presence and concentration of bio-molecules in a biological sample are provided in the form of polymer brushes, which comprise a substrate having a surface that is modified with a water-dispersible or water-soluble polymer segment having functional groups that bind probes. The method of synthesis of such sensors preferably includes use of controlled free radical polymerization techniques, and in particular the use of an iniferter initiator, which allows for controlled architecture polymers to modify the surface of the substrate. In this manner functional groups in the polymer chain are removed from the surface, which allows for solution chemistry to be more realistically reproduced with the benefits of a solid bound probe.

公开(公告)号：DE60027309D1

公开(公告)日：2006-05-24

申请号：DE60027309

申请日：2000-07-03

Applicant: SYMYX TECHNOLOGIES INC

Inventor： KLAERNER GERRIT ,  NIELSEN B ,  MANSKY PAUL ,  BENOIT DIDIER ,  CHARMOT DOMINIQUE ,  JANDELEIT BERND ,  MAZZOLA T

IPC: C08F292/00 ,  C08F4/00 ,  C08F220/54 ,  C08F220/58 ,  C12Q1/68 ,  G01N27/447 ,  G01N33/48 ,  G01N33/543

Abstract: Sensors for determining the presence and concentration of bio-molecules in a biological sample are provided in the form of polymer brushes, which comprise a substrate having a surface that is modified with a water-dispersible or water-soluble polymer segment having functional groups that bind probes. The method of synthesis of such sensors preferably includes use of controlled free radical polymerization techniques, and in particular the use of an iniferter initiator, which allows for controlled architecture polymers to modify the surface of the substrate. In this manner functional groups in the polymer chain are removed from the surface, which allows for solution chemistry to be more realistically reproduced with the benefits of a solid bound probe.

公开(公告)号：AU2003219972A1

公开(公告)日：2003-09-22

申请号：AU2003219972

申请日：2003-02-26

Applicant: SYMYX TECHNOLOGIES INC

Inventor： CHARMOT DOMINIQUE ,  HAJDUK DAMIAN ,  KLAERNER GERRIT ,  NGUYEN SON HOAI ,  PIOTTI MARCELO ,  LIN SHAN ,  BENOIT DIDER

IPC: G01N27/447

公开(公告)号：AU5785400A

公开(公告)日：2001-01-22

申请号：AU5785400

申请日：2000-07-03

Applicant: SYMYX TECHNOLOGIES INC

Inventor： KLAERNER GERRIT ,  NIELSEN RALPH B ,  MANSKY PAUL ,  BENOIT DIDIER ,  CHARMOT DOMINIQUE ,  JANDELEIT BERND ,  MAZZOLA LAURA T

IPC: C08F4/00 ,  C08F220/54 ,  C08F220/58 ,  G01N27/447 ,  G01N33/543 ,  C08F292/00 ,  G01N33/48 ,  C12Q1/68

Abstract: Sensors for determining the presence and concentration of bio-molecules in a biological sample are provided in the form of polymer brushes, which comprise a substrate having a surface that is modified with a water-dispersible or water-soluble polymer segment having functional groups that bind probes. The method of synthesis of such sensors preferably includes use of controlled free radical polymerization techniques, and in particular the use of an iniferter initiator, which allows for controlled architecture polymers to modify the surface of the substrate. In this manner functional groups in the polymer chain are removed from the surface, which allows for solution chemistry to be more realistically reproduced with the benefits of a solid bound probe.