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    Hollow fiber membrane module for use in production of chemical substance, and process for production of chemical substance
    11.
    发明专利
    Hollow fiber membrane module for use in production of chemical substance, and process for production of chemical substance 未知

    公开(公告)号：AU2010319104A1

    公开(公告)日：2012-05-17

    申请号：AU2010319104

    申请日：2010-11-10

    Applicant: TORAY INDUSTRIES

    Inventor： TAKEUCHI NORIHIRO ,  MINEGISHI SHIN-ICHI ,  CHEON JIHOON ,  NISHIDA MAKOTO ,  MIMITSUKA TAKASHI ,  SUZUKI HIRONOBU ,  YAMADA KATSUSHIGE ,  SAWAI HIDEKI ,  KUMO ICHIRO

    IPC: B01D63/04 ,  B01D63/00 ,  B01D71/34 ,  C12M1/12 ,  C12M3/06 ,  C12N15/09 ,  C12P7/56

    Abstract: Disclosed is a hollow fiber membrane module (1) for use in the production of a chemical substance, which can be used in the continuous fermentation that comprises filtrating a fermentation culture of a microorganism or a cultured cell through a hollow fiber membrane, collecting a chemical substance from a filtrate, retaining a concentrated solution in the fermentation culture or refluxing the concentrated solution, and further adding a fermentation raw material to the fermentation culture. In the hollow fiber membrane module (1), multiple hollow fiber membrane bundles are accommodated in a tubular case, at least one end part of each of the hollow fiber membrane bundles is fixed onto the tubular case in such a manner that the end surface of each of the hollow fiber membranes is opened by means of a hollow-fiber-membrane-bundling material, and the hollow-fiber-membrane-bundling material comprises a synthetic resin that exhibits a hardness retention rate of 95% or more after the material is brought into contact with a saturated water vapor at 121°C for 24 hours. The hollow fiber membrane module (1) can keep substance productivity at a high level and can be used in the production of a chemical substance by a sterilizable continuous fermentation method.

    METHOD FOR PRODUCING LACTIC ACID AND METHOD FOR PRODUCING POLYLACTIC ACID
    12.
    发明专利
    METHOD FOR PRODUCING LACTIC ACID AND METHOD FOR PRODUCING POLYLACTIC ACID 未知

    公开(公告)号：SG172400A1

    公开(公告)日：2011-08-29

    申请号：SG2011046992

    申请日：2009-12-25

    Applicant: TORAY INDUSTRIES

    Inventor： SAWAI KENJI ,  SAWAI HIDEKI ,  MIMITSUKA TAKASHI ,  ITO MASATERU ,  YAMADA KATSUSHIGE ,  KAWAMURA KENJI ,  MINEGISHI SHIN-ICHI ,  NAKAGAWA IZUMI ,  NAGANO TATSUYA

    Abstract: Lactic acid obtained by a method for producing lactic acid, the method comprising: (A) a step of continuous fermentation wherein a fermentation culture medium of a microorganism having an ability of lactic acid fermentation is filtered 5 through a porous membrane having an average pore size of not less than 0.01 ttm and less than 1 pm with a transmembrane pressure difference within the range of 0.1 to 20 kPa, and the permeate is collected, while retaining the non-permeated liquid in orreturning the non-permeated liquid to the culture, and adding a fermentation feedstock to the culture: (B) a step of filtering the permeate obtained in Step (A) 10 through a nanofdtration membrane; and (C) a step of distilling the permeate obtained in Step (B) under a pressure of not less than 1 Pa and not more than atmospheric pressure, at 25°C to 200°C to recover lactic acid; comprises only small amounts of impurities, and a polylactic acid obtained using the lactic acid as a raw material has excellent thermal stability, mechanical strength and hue.

    Method for producing chemical and continuous culture system
    13.
    发明专利
    Method for producing chemical and continuous culture system 未知

    公开(公告)号：AU2009299152A1

    公开(公告)日：2010-04-08

    申请号：AU2009299152

    申请日：2009-09-16

    Applicant: TORAY INDUSTRIES

    Inventor： MIMITSUKA TAKASHI ,  ISHII KENTARO ,  MORITA KEN ,  HIGASA MASASHI ,  SAWAI KENJI ,  SAWAI HIDEKI ,  YAMADA KATSUSHIGE ,  MINEGISHI SHINICHI

    IPC: C12P1/00 ,  C12M1/00 ,  C12M3/00 ,  C12N15/09

    Abstract: To control flow velocity of a culture liquid inside a membrane separation tank without giving influences to culture conditions in the fermentation tank, and also suppress precipitation of microorganisms or culture cells so that the production efficiency of the chemical product can be improved, in a method for producing a chemical product including the steps of: cultivating microorganisms or culture cells in a fermentation tank; transferring a culture liquid from the fermentation tank to a membrane separation tank so as to filter the culture liquid through a separation membrane; and collecting a fermentation product from a filtration liquid as the chemical product while refluxing an unfiltered culture liquid that has not been filtered so as to be joined to the culture liquid on an upstream side of the membrane separation tank, one portion of the culture liquid to be transferred from the fermentation tank is allowed to bypass the membrane separation tank depending on a pressure at the culture liquid flow-in side of the membrane separation tank.

    METHOD FOR PRODUCING CHEMICAL BY CONTINUOUS FERMENTATION
    14.
    发明专利
    METHOD FOR PRODUCING CHEMICAL BY CONTINUOUS FERMENTATION 未知

    公开(公告)号：CA2820876C

    公开(公告)日：2019-05-14

    申请号：CA2820876

    申请日：2011-12-08

    Applicant: TORAY INDUSTRIES

    Inventor： KANAMORI SATOKO ,  CHEON JIHOON ,  TAKEUCHI NORIHIRO ,  NISHIDA MAKOTO ,  TANAKA YUJI ,  MIMITSUKA TAKASHI

    IPC: C12P13/04 ,  C12P13/00

    Abstract: A method for producing a chemical through continuous fermentation, the method including: (a) culturing a cell in a culture medium in a fermentor to ferment a feedstock to produce a chemical; (b) conducting filtration of the culture medium by using a separation membrane module; (c) separating a permeate containing the chemical from the culture medium while retaining a non-permeated liquid in the fermentor, and (d) supplying a gas from at least one of a lower portion of the separation membrane module and a pipe communicating between the fermentor and the separation membrane module so as to adjust a gas linear velocity in the separation membrane module to 0.15 cm/s to 70 cm/s while supplying the separation membrane module with a liquid.

    Method for producing chemical by continuous fermentation
    19.
    发明专利
    Method for producing chemical by continuous fermentation 未知

    公开(公告)号：AU2011339328A1

    公开(公告)日：2013-07-04

    申请号：AU2011339328

    申请日：2011-12-08

    Applicant: TORAY INDUSTRIES

    Inventor： KANAMORI SATOKO ,  CHEON JIHOON ,  MIMITSUKA TAKASHI ,  TAKEUCHI NORIHIRO ,  NISHIDA MAKOTO ,  TANAKA YUJI

    IPC: C12P13/04 ,  C12P13/00

    Abstract: A method for producing a chemical by continuous fermentation, said method comprising: (a) fermenting a starting material by culturing cells in a liquid culture medium in a fermentation tank to form a chemical; (b) filtering the liquid culture medium by using a separation membrane module; (c) while holding within the fermentation tank the liquid not permeating in the filtration, separating the permeating liquid, which contains the chemical, from the liquid culture medium; and (d) while supplying a liquid to the separation membrane module, supplying a gas from the lower part of the separation membrane module and/or a pipe, said pipe connecting the fermentation tank to the separation membrane module, so as to control the linear gas velocity in the separation membrane module to 0.15-70 cm/s inclusive.

    HOLLOW FIBER MEMBRANE MODULE FOR USE IN PRODUCTION OF CHEMICAL SUBSTANCE, AND PROCESS FOR PRODUCTION OF CHEMICAL SUBSTANCE
    20.
    发明专利
    HOLLOW FIBER MEMBRANE MODULE FOR USE IN PRODUCTION OF CHEMICAL SUBSTANCE, AND PROCESS FOR PRODUCTION OF CHEMICAL SUBSTANCE 未知

    公开(公告)号：CA2778765A1

    公开(公告)日：2011-05-19

    申请号：CA2778765

    申请日：2010-11-10

    Applicant: TORAY INDUSTRIES

    Inventor： TAKEUCHI NORIHIRO ,  MINEGISHI SHIN-ICHI ,  CHEON JIHOON ,  NISHIDA MAKOTO ,  MIMITSUKA TAKASHI ,  SUZUKI HIRONOBU ,  YAMADA KATSUSHIGE ,  SAWAI HIDEKI ,  KUMO ICHIRO

    IPC: B01D63/04 ,  B01D63/00 ,  B01D71/34 ,  C12M1/12 ,  C12M3/06 ,  C12N15/09 ,  C12P7/56

    Abstract: Disclosed is a hollow fiber membrane module (1) for use in the production of a chemical substance, which can be used in the continuous fermentation that comprises filtrating a fermentation culture of a microorganism or a cultured cell through a hollow fiber membrane, collecting a chemical substance from a filtrate, retaining a concentrated solution in the fermentation culture or refluxing the concentrated solution, and further adding a fermentation raw material to the fermentation culture. In the hollow fiber membrane module (1), multiple hollow fiber membrane bundles are accommodated in a tubular case, at least one end part of each of the hollow fiber membrane bundles is fixed onto the tubular case in such a manner that the end surface of each of the hollow fiber membranes is opened by means of a hollow-fiber-membrane-bundling material, and the hollow-fiber-membrane-bundling material comprises a synthetic resin that exhibits a hardness retention rate of 95% or more after the material is brought into contact with a saturated water vapor at 121°C for 24 hours. The hollow fiber membrane module (1) can keep substance productivity at a high level and can be used in the production of a chemical substance by a sterilizable continuous fermentation method.

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