-
公开(公告)号：AU2020396807A1
公开(公告)日：2022-07-21
申请号：AU2020396807
申请日：2020-12-04
Applicant: UNIV HEALTH NETWORK
Inventor： BRAY MARK R , MASON JACQUELINE M , FLETCHER GRAHAM
IPC: A61K31/5377 , A61K31/194 , A61P35/02 , C07C57/15 , C07D413/14
Abstract: The invention is related to a method of treating a subject with acute myeloid leukemia, acute lymphoblastic leukemia, chronic myeloid leukemia, non-Hodgkin's lymphoma, Burkitt lymphoma, or diffuse large B-cell lymphoma, or myelodysplastic syndrome by administration of Compound (I): (I), or a pharmaceutically acceptable salt thereof.
-
公开(公告)号：SG11202109708TA
公开(公告)日：2021-10-28
申请号：SG11202109708T
申请日：2020-03-11
Applicant: UNIV HEALTH NETWORK
Inventor： BROKX RICHARD , MASON JACQUELINE M , BRAY MARK R
IPC: C07K16/18 , A61K39/395 , C12N15/13 , C12P21/08
Abstract: The invention provides novel anti-TSG-6 antibodies, pharmaceutical compositions comprising such antibodies, and therapeutic methods of using such antibodies and pharmaceutical compositions for the treatment of diseases such as cancer or autoimmune disease.
-
公开(公告)号：SG11202107663UA
公开(公告)日：2021-08-30
申请号：SG11202107663U
申请日：2020-01-16
Applicant: UNIV HEALTH NETWORK
Inventor： BROKX RICHARD , MASON JACQUELINE M , BRAY MARK R
IPC: A61K39/395 , C07K16/28 , A61P29/00 , A61P35/00 , A61P35/02 , A61P37/02 , A61P37/06 , C12N15/13 , C12P21/08
Abstract: The invention provides novel anti-LILRB3 antibodies, pharmaceutical compositions comprising such antibodies, and therapeutic methods of using such antibodies and pharmaceutical compositions for the treatment of diseases such as cancer, autoimmune disease, or allergic inflammation This invention can also be used to modulate osteoclast differentiation.
-
公开(公告)号：AU2020209367A1
公开(公告)日：2021-08-19
申请号：AU2020209367
申请日：2020-01-16
Applicant: UNIV HEALTH NETWORK
Inventor： BROKX RICHARD , MASON JACQUELINE M , BRAY MARK R
IPC: C07K16/28 , A61K39/395 , A61P29/00 , A61P35/00 , A61P35/02 , A61P37/02 , A61P37/06 , C12N15/13 , C12P21/08
Abstract: The invention provides novel anti-LILRB3 antibodies, pharmaceutical compositions comprising such antibodies, and therapeutic methods of using such antibodies and pharmaceutical compositions for the treatment of diseases such as cancer, autoimmune disease, or allergic inflammation. This invention can also be used to modulate osteoclast differentiation.
-
公开(公告)号：AU2018328773A1
公开(公告)日：2020-03-26
申请号：AU2018328773
申请日：2018-09-07
Applicant: UNIV HEALTH NETWORK
Inventor： MASON JACQUELINE M , BRAY MARK R , MAK TAK WAH , FLETCHER GRAHAM
IPC: C07D413/10 , A61K31/5377 , A61K39/395 , A61P35/00
Abstract: Provided herein are methods of treating cancer using an effective amount of a compound represented by the formula (Formula (I)) or a pharmaceutically acceptable salt thereof and an effective amount of an immune checkpoint inhibitor. Also provided are compositions comprising the same compound represented by the formula shown above or a pharmaceutically acceptable salt thereof and an immune checkpoint inhibitor.
-
Patent Agency Ranking
公开(公告)号：AU2021257439A1
公开(公告)日：2022-12-15
申请号：AU2021257439
申请日：2021-04-12
Applicant: UNIV HEALTH NETWORK
Inventor： BRAY MARK R , MASON JACQUELINE M , WEI XIN , DUNCAN GORDON
IPC: A61P37/02 , A61K31/4436 , C07D495/04
Abstract: Disclosed herein is a method of treating a subject with aberrant cytokine release from a disease or condition or at risk of developing aberrant cytokine release from a disease or condition. The method comprises administering to the subject an effective amount of a compound represented by structural formula (I): (I) or a pharmaceutically acceptable salt thereof. The variables in structural formula (I) are as described herein.
-
公开(公告)号：SG11202108837WA
公开(公告)日：2021-09-29
申请号：SG11202108837W
申请日：2020-02-14
Applicant: UNIV HEALTH NETWORK
Inventor： BROKX RICHARD , MASON JACQUELINE M , BRAY MARK R
IPC: C07K16/28 , A61K39/395 , A61P31/00 , A61P35/00 , A61P35/02 , A61P37/02 , C12N5/10 , C12N15/13 , C12P21/08
Abstract: The invention provides novel anti-FCMR antibodies, pharmaceutical compositions comprising such antibodies, and therapeutic methods of using such antibodies and pharmaceutical compositions for the treatment of diseases such as cancer or autoimmune disease.
-
公开(公告)号：AU2020222408A1
公开(公告)日：2021-09-09
申请号：AU2020222408
申请日：2020-02-14
Applicant: UNIV HEALTH NETWORK
Inventor： BROKX RICHARD , MASON JACQUELINE M , BRAY MARK R
IPC: C07K16/28 , A61K39/395 , A61P31/00 , A61P35/00 , A61P35/02 , A61P37/02 , C12N5/10 , C12N15/13 , C12P21/08
Abstract: The invention provides novel anti-FCMR antibodies, pharmaceutical compositions comprising such antibodies, and therapeutic methods of using such antibodies and pharmaceutical compositions for the treatment of diseases such as cancer or autoimmune disease.
-
公开(公告)号：CA3126295A1
公开(公告)日：2020-07-23
申请号：CA3126295
申请日：2020-01-16
Applicant: UNIV HEALTH NETWORK
Inventor： BROKX RICHARD , MASON JACQUELINE M , BRAY MARK R
IPC: C07K16/28 , A61K39/395 , A61P29/00 , A61P35/00 , A61P35/02 , A61P37/02 , A61P37/06 , C12N15/13 , C12P21/08
Abstract: The invention provides novel anti-LILRB3 antibodies, pharmaceutical compositions comprising such antibodies, and therapeutic methods of using such antibodies and pharmaceutical compositions for the treatment of diseases such as cancer, autoimmune disease, or allergic inflammation. This invention can also be used to modulate osteoclast differentiation.
-
公开(公告)号：CA3074876A1
公开(公告)日：2019-03-14
申请号：CA3074876
申请日：2018-09-07
Applicant: UNIV HEALTH NETWORK
Inventor： MASON JACQUELINE M , BRAY MARK R , MAK TAK WAH , FLETCHER GRAHAM
IPC: A61K31/5377 , A61K39/395 , A61P35/00 , C07D413/10
Abstract: Provided herein are methods of treating cancer using an effective amount of a compound represented by the formula (Formula (I)) or a pharmaceutically acceptable salt thereof and an effective amount of an immune checkpoint inhibitor. Also provided are compositions comprising the same compound represented by the formula shown above or a pharmaceutically acceptable salt thereof and an immune checkpoint inhibitor.
-
-
-
-
-
-
-
-
-
Search Results
30
records
(took 0.022 seconds)
